Retroviruses and Wild Mice: An Historical and Personal Perspective

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

1982 • 2,170 citations

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

Delay of Disease Development in Transgenic Plants That Express the Tobacco Mosaic Virus Coat Protein Gene

1986 • 1,324 citations

Human gene therapy comes of age

1992 • 927 citations

ONCOGENES OF RNA TUMOR VIRUSES AS DETERMINANTS OF CANCER

1969 • 868 citations

A new class of murine leukemia virus associated with development of spontaneous lymphomas.

1977 • 718 citations

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

1989 • 692 citations

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor

1991 • 552 citations

Genetic Control Of Murine Viral Leukemogenesis

1973 • 452 citations

Clonal cell lines from a feral mouse embryo which lack host-range restrictions for murine leukemia viruses

1975 • 410 citations

Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus.

1994 • 377 citations

"Spontaneous" Leukemia Developing in G3H Mice Following Inoculation, In Infancy, with AK-Emkemic.

1951 • 371 citations

Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class

1976 • 351 citations

Viruses in naturally occurring cancers

1980 • 333 citations

Origins of Inbred Mice

1978 • 263 citations

Human retrovirology: HTLV

1991 • 249 citations

Role of endogenous retroviruses as mutagens: The hairless mutation of mice

1988 • 221 citations

Amphotropic host range of naturally occuring wild mouse leukemia viruses

1976 • 210 citations

Endogenous mammary tumour virus DNA varies among wild mice and segregates during inbreeding

1979 • 207 citations

Truncation of the c-myb gene by a retroviral integration in an interleukin 3-dependent myeloid leukemia cell line.

1986 • 204 citations

Pathogenic Properties, and "Vertical" Transmission of the Mouse Leukemia Agent.

1951 • 201 citations

A Spontaneous Lower Motor Neuron Disease Apparently Caused by Indigenous Type-C RNA Virus in Wild Mice2

1973 • 200 citations

Host Susceptibility to endogenous viruses: defective, glycoprotein-expressing proviruses interfere with infections

1981 • 161 citations

Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues

1993 • 158 citations

Characterization of a molecularly cloned retroviral sequence associated with Fv-4 resistance

1985 • 149 citations

Genetic factors in the natural history of murine leukemia virus infection: G. H. A. Clowes Memorial Lecture.

1973 • 137 citations

Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death.

1987 • 133 citations

Human retrovirology : HTLV

1990 • 114 citations

A viral interference test for mouse leukemia viruses

1967 • 109 citations

Correlation of cell-surface phenotype with the establishment of interleukin 3-dependent cell lines from wild-mouse murine leukemia virus-induced neoplasms.

1985 • 104 citations

Hereditary Infections With Mammary Tumor Viruses in Mice

1969 • 104 citations

LOWER MOTOR NEURON DEGENERATION ASSOCIATED WITH TYPE C RNA VIRUS INFECTION IN MICE

1974 • 101 citations

Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection

1982 • 100 citations

The Lake Casitas wild mouse:Evolving genetic resistance to retroviral disease

1991 • 94 citations

Retroviral Spongiform Polioencephalomyelopathy

1985 • 92 citations

Diverse wild mouse origins of xenotropic, mink cell focus-forming, and two types of ecotropic proviral genes

1987 • 81 citations

Identification of mouse chromosomes required for murine leukemia virus replication

1977 • 81 citations

Understanding Breast Cancer: Clinical and Laboratory Concepts

1984 • 79 citations

Comparative studies on the structural phosphoproteins of mammalian type C viruses

1975 • 79 citations

Cas-Br-E murine leukemia virus: sequencing of the paralytogenic region of its genome and derivation of specific probes to study its origin and the structure of its recombinant genomes in leukemic tissues

1986 • 77 citations

Retroviruses and Mouse Embryos: A Rapid Model for Neurovirulence and Transplacental Antiviral Therapy

1987 • 76 citations

Murine retrovirus-induced spongiform encephalopathy: Productive infection of microglia and cerebellar neurons in accelerated CNS disease

1991 • 76 citations

Isolation of a Neurotropic Type C Virus

1973 • 74 citations

Integration site preferences of endogenous retroviruses

1991 • 74 citations

Induction of Disseminated Virulent Cytomegalovirus Infection by Immunosuppression of Naturally Chronically Infected Wild Mice

1974 • 73 citations

Cancer Crusade: The Story of the National Cancer Act of 1971

1978 • 71 citations

Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor

1991 • 70 citations

A unique sequence related to the ecotropic murine leukemia virus is associated with the Fv-4 resistance gene.

1984 • 69 citations

Virus-Host Interactions and the Pathogenesis of Murine and Human Oncogenic Retroviruses

1991 • 69 citations

On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture.

1974 • 68 citations

Cellular expression of murine leukemia virus gp70-related antigen on thymocytes of uninfected mice correlates with Fv-4 gene-controlled resistance to friend leukemia virus infection

1983 • 67 citations

<italic>Fv-4:</italic> Gene Controlling Resistance to NB-Tropic Friend Murine Leukemia Virus. Distribution in Wild Mice, Introduction Into Genetic Background of BALB/c Mice, and Mapping of Chromosomes<xref ref-type="fn" rid="FN2">2</xref>

1981 • 64 citations

Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice.

1980 • 59 citations

Age-dependent resistance to murine retrovirus-induced spongiform neurodegeneration results from central nervous system-specific restriction of virus replication

1991 • 58 citations

Horizontal transmission of murine retroviruses

1987 • 57 citations

Transgenic Fv-4 mice resistant to Friend virus

1993 • 56 citations

Mouse chromosome 5 codes for ecotropic murine leukaemia virus cell-surface receptor

1978 • 55 citations

Cancer Crusade: The Story of the National Cancer Act of 1971, by Richard A. Rettig

1978 • 49 citations

Enhanced gene expression of the murine ecotropic retroviral receptor and its human homolog in proliferating cells

1992 • 47 citations

Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas

1991 • 47 citations

The epidemiology and virology of C-type virus-associated hematological cancers and related diseases in wild mice.

1976 • 46 citations

Spontaneous Tumors of Aging Wild House Mice, Incidence, Pathology, and C-Type Virus Expression2

1973 • 46 citations

Unusually High Incidence of Spontaneous Lymphomas in Wild House Mice2

1973 • 45 citations

Spontaneous germ line virus infection and retroviral insertional mutagenesis in eighteen transgenic Srev lines of mice.

1989 • 42 citations

Studies of Congenital Transmission of a Leukemia Virus in Mice.

1961 • 41 citations

Substitution of the U3 long terminal repeat region of the neurotropic Cas-Br-E retrovirus affects its disease-inducing potential

1990 • 40 citations

Neurological disease induced in transgenic mice expressing the env gene of the Cas-Br-E murine retrovirus.

1993 • 40 citations

Congenital Transmission of Murine Leukemia Virus From Wild Mice Prone to the Development of Lymphoma and Paralysis<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>

1979 • 40 citations

Analysis of proviruses integrated in Fli-1 and Evi-1 regions in Cas-Br-E MuLV-induced non-T-, non-B-cell leukemias

1992 • 36 citations

Biological Effects of Urban Air Pollution

1966 • 36 citations

Characterization of a highly oncogenic murine leukemia virus from wild mice

1982 • 33 citations

Types Band C RNA Virus in Breast Tissue and Milk of Wild Mice2

1973 • 32 citations

Wild mouse RNA tumor viruses. A nongenetically transmitted virus group closely related to exogenous leukemia viruses of laboratory mouse strains.

1979 • 32 citations

Characterization of Purely Ecotropic and Amphotropic Naturally Occurring Wild Mouse Leukemia Viruses

1977 • 32 citations

Molecular characterization of the Akvr-1 restriction gene: a defective endogenous retrovirus-borne gene identical to Fv-4r

1987 • 32 citations

Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus

1983 • 31 citations

C-Type RNA Tumour Virus Genome Expression in Wild House Mice

1971 • 30 citations

Vertical transmission of murine leukemia virus.

1969 • 29 citations

Understanding breast cancer : clinical and laboratory concepts

1983 • 28 citations

Amphotropic proviral envelope sequences are absent from the Mus germ line

1987 • 27 citations

Structural analysis of the major envelope glycoprotein (gp70) of the amphotropic and ecotropic type C viruses of wild mice

1978 • 27 citations

Pulmonary Changes in 7,000 Mice Following Prolonged Exposure to Ambient and Filtered Los Angeles Air

1970 • 26 citations

Mammary Tumor Virus Particles in the Submaxillary Gland, Seminal Vesicle, and Nonmammary Tumors of Wild Mice2

1975 • 25 citations

Neurotropic Cas-BR-E murine leukemia virus harbors several determinants of leukemogenicity mapping in different regions of the genome

1985 • 25 citations

Immunopathology of natural and experimental lymphomas induced by wild mouse leukemia virus.

1981 • 25 citations

Genetic diversity in leukemia-prone feral house mice infected with murine leukemia virus

1980 • 25 citations

Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system

1993 • 24 citations

Genetic control of type C virus of wild mice

1976 • 24 citations

The Pathogenesis of Murine Retroviral Infection of the Central Nervous System

1993 • 24 citations

Subviral components of a wild mouse embryo-derived type C oncornavirus

1973 • 23 citations

Development of a mouse mammary tumor virus-negative mouse strain: a new system for the study of mammary carcinogenesis

1982 • 20 citations

Inefficient Humoral Immune Response of Lymphoma-Prone Wild Mice to Persistent Leukemia Virus Infection2

1976 • 19 citations

Type C Virus Expression in Lymphoma-Paralysis-Prone Wild Mice2

1976 • 19 citations

Isolation and characterization of new ecotropic murine leukemia viruses after passage of an amphotropic virus in NIH Swiss Mice

1983 • 19 citations

Brief Communication: Spontaneous Tumors and C-Type Virus in PolyomaInfected Aging Wild House Mice 2

1974 • 17 citations

Prevention of Paralysis and Suppression of Lymphoma in Wild Mice by Passive Immunization to Congenially Transmitted Murine Leukemia Virus23

1980 • 16 citations

Virus-specific cytotoxic lymphocyte response in a neurotropic murine leukemia virus infection

1991 • 15 citations

Genetic analysis of the effects of Mtv-2 on the T cell repertoire in the WXG-2 mouse strain

1992 • 15 citations

Prevention of Lower Limb Paralysis by Neutralization of Type-C RNA Virus in Wild Mice2

1974 • 15 citations

Resistance of fibroblasts and hematopoietic cells to ecotropic murine leukemia virus infection; an Akvr‐1^R gene effect

1983 • 14 citations

Genetic relationship of wild mouse amphotropic virus to murine ecotropic and xenotropic viruses

1978 • 13 citations

Prevalence of Murine Mammary Tumor Virus Antibody and Antigens in Normal and Tumor-Bearing Feral Mice<xref ref-type="fn" rid="FN2">2</xref>

1978 • 12 citations

Characterization of genome structure of amphotropic and ecotropic wild mouse retroviruses

1982 • 11 citations

Retrovirus antigens in brains of mice with scrapie- and murine leukemia virus-induced spongiform encephalopathy

1982 • 11 citations

Hyperplastic and Neoplastic Changes in the Mammary Glands of Feral Mice Free of Endogenous Mouse Mammary Tumor Virus Provirus<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1984 • 10 citations

Suppression of Infectious Murine Leukemia Virus in Wild Mice ( Mus musculus ) by Passive Immunization: Brief Communication 2 3

1977 • 10 citations

Wild rat type C virus: Isolation and characterization

1978 • 9 citations

Transfer, by selective breeding, of the pathogenic Mtv-2 endogenous provirus from the GR strain to a wild mouse line free of endogenous and exogenous mouse mammary tumor virus

1986 • 8 citations

Prevalence and Distribution of Murine Mammary Tumor Virus Antigen Detectable by Immunocytochemistry in Spontaneous Breast Tumors of Wild Mice<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 6 citations