The Zona Pellucida “Receptors”

Mechanisms of Fertilization in Mammals

1981 • 782 citations

Oxford reviews of reproductive biology

1981 • 752 citations

ZONA PELLUCIDA GLYCOPROTEINS

1988 • 730 citations

Mammalian sperm-egg interaction: Identification of a glycoprotein in mouse egg zonae pellucidae possessing receptor activity for sperm

1980 • 704 citations

Structure and function of the zona pellucida: Identification and characterization of the proteins of the mouse oocyte's zona pellucida

1980 • 618 citations

Sperm-egg interactions in the mouse: Sequence of events and induction of the acrosome reaction by a zona pellucida glycoprotein

1983 • 603 citations

O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity

1985 • 587 citations

Mechanism and control of animal fertilization

1983 • 478 citations

Profile of a mammalian sperm receptor1,2

1990 • 367 citations

95 kd sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding

1989 • 341 citations

Fertilization and Embryonic Development In Vitro

1981 • 332 citations

Identification of a secondary sperm receptor in the mouse egg zona pellucida: Role in maintenance of binding of acrosome-reacted sperm to eggs

1988 • 330 citations

Cloning and characterization of zona pellucida genes and cDNAs from a variety of mammalian species: The ZPA, ZPB and ZPC gene families

1994 • 328 citations

Mouse egg extracellular coat is a matrix of interconnected filaments possessing a structural repeat

1985 • 300 citations

Autoradiographic visualization of the mouse egg's sperm receptor bound to sperm.

1986 • 276 citations

The mammalian egg

1961 • 275 citations

Early Events in Mammalian Fertilization

1987 • 236 citations

Enzymatic dissection of the functions of the mouse egg's receptor for sperm

1984 • 236 citations

Identification of a ZP3-binding protein on acrosome-intact mouse sperm by photoaffinity crosslinking.

1990 • 219 citations

Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction.

1989 • 218 citations

Vaccination with a Synthetic Zona Pellucida Peptide Produces Long-Term Contraception in Female Mice

1989 • 213 citations

Immunization with Zona Pellucida Proteins Results in Abnormal Ovarian Follicular Differentiation and Inhibition of Gonadotropin-Induced Steroid Secretion*

1984 • 190 citations

Characterization of a proteinase that cleaves zona pellucida glycoprotein ZP2 following activation of mouse eggs

1989 • 189 citations

Regulation of mouse gamete interaction by a sperm tyrosine kinase.

1992 • 156 citations

A Comparative Overview of Mammalian Fertilization

1991 • 155 citations

Oocyte-Specific Expression of Mouse Zp-2: Developmental Regulation of the Zona Pellucida Genes

1990 • 155 citations

Structural and functional relationships between mouse and hamster zona pellucida glycoproteins

1990 • 152 citations

The status of acrosomal caps of hamster spermatozoa immediately before fertilization in vivo

1984 • 151 citations

Structure of the Mouse Egg Extracellular Coat, the Zona Pellucida

1991 • 148 citations

Evidence for a guanine nucleotide-binding regulatory protein in invertebrate and mammalian sperm. Identification by islet-activating protein-catalyzed ADP-ribosylation and immunochemical methods.

1986 • 145 citations

Zona Pellucida Composition: Species Cross Reactivity and Contraceptive Potential of Antiserum to a Purified Pig Zona Antigen (PPZA)

1981 • 138 citations

Egg cortical granule N-acetylglucosaminidase is required for the mouse zona block to polyspermy.

1993 • 137 citations

Biosynthesis of the major zona pellucida glycoprotein secreted by oocytes during mammalian oogenesis

1982 • 121 citations

Oocyte-specific expression of mouse Zp-2: developmental regulation of the zona pellucida genes.

1990 • 120 citations

Subcellular immunochemical localization of acrosin in human spermatozoa during the acrosome reaction and zona pellucida penetration

1988 • 113 citations

Differential binding of gold-labeled zona pellucida glycoproteins mZP2 and mZP3 to mouse sperm membrane compartments

1991 • 109 citations

Acrosin shows zona and fucose binding, novel properties for a serine proteinase

1987 • 107 citations

Mammalian sperm interaction with extracellular matrices of the egg.

1989 • 105 citations

Surface architecture of the mouse and hamster zona pellucida and oocyte

1980 • 100 citations

Conservation of Mammalian Secondary Sperm Receptor Genes Enables the Promoter of the Human Gene to Function in Mouse Oocytes

1993 • 91 citations

Mouse Zp1 Encodes a Zona Pellucida Protein Homologous to Egg Envelope Proteins in Mammals and Fish

1995 • 90 citations

Human zona pellucida during in vitro fertilization: An ultrastructural study using saponin, ruthenium red, and osmium‐thiocarbohydrazide

1992 • 81 citations

How the Egg Regulates Sperm Function during Gamete Interaction: Facts and Fantasies1

1991 • 81 citations

Development of contraceptive vaccines for humans using antigens derived from gametes (spermatozoa and zona pellucida) and hormones (human chorionic gonadotrophin): current status

1995 • 80 citations

Acrosin activation follows its surface exposure and precedes membrane fusion in human sperm acrosome reaction

1990 • 77 citations

Cytochemical Demonstration of Acrosomal Proteinase in Mammalian and Avian Spermatozoa by a Silver Proteinate Method

1972 • 76 citations

Effects of Phorbol Esters and a Diacylglycerol on the Mouse Sperm Acrosome Reaction Induced by the Zona Pellucida1

1987 • 75 citations

Monoclonal antibodies as probes of the distribution of ZP-2, the major sulfated glycoprotein of the murine zona pellucida.

1984 • 74 citations

Fucoidin inhibits attachment of guinea pig spermatozoa to the zona pellucida through binding to the inner acrosomal membrane and equatorial domains

1984 • 71 citations

Regulation of mammalian fertilization by zona pellucida glycoproteins.

1990 • 68 citations

Biology and structure of the zona pellucida: a target for immunocontraception

1994 • 65 citations

Contraceptive potential of antibodies to the zona pellucida

1988 • 63 citations

Is the sperm-binding capability of the zona pellucida linked to its surface structure? A scanning electron microscopic study of human in vitro fertilization

1988 • 62 citations

Location of the PH-20 Protein on Acrosome-Intact and Acrosome-Reacted Spermatozoa of Cynomolgus Macaques1

1995 • 62 citations

Tissue distribution of β1- and β2-subunits of regulatory guanine nucleotide-binding proteins

1989 • 52 citations

Comparative Structure and Function of Mammalian Zonae Pellucidae

1991 • 49 citations

Blocking of Human Sperm-Zona Interaction by Monoclonal Antibodies to a Glycoprotein Family (ZP4) of Porcine Zona Pellucida1

1991 • 48 citations

Computer prediction of potential immunogenic determinants from protein amino acid sequence

1987 • 45 citations

Hapten mimic elicits antibodies recognizing prostaglandin E2.

1978 • 42 citations

Cloning, sequencing and oocyte-specific expression of the marmoset sperm receptor protein, ZP3

1993 • 40 citations

Regulators of sperm function: Composition of the human zona pellucida and modifications following fertilization

1995 • 39 citations

Identification of Mouse ZP3 Protein in Mammalian Oocytes with Antisera against Synthetic ZP3 Peptides1

1994 • 35 citations

Migration of the guinea pig sperm membrane protein PH-20 from one localized surface domain to another does not occur by a simple diffusion-trapping mechanism

1991 • 35 citations

The Mammalian Egg Coat: Structure and Function

2011 • 34 citations

Immunodetection of acrosin during the acrosome reaction of hamster, guinea-pig and human spermatozoa.

1992 • 32 citations

Localization of Rabbit Sperm Acrosin during the Acrosome Reaction Induced by Immobilized Zona Matrix1

1991 • 32 citations

The Mouse Egg Receptor For Sperm: A Multifunctional Zona Pellucida Glycoprotein

1989 • 32 citations

Fertilistion in sea urchins: how many different molecules are involved in gamete interaction and fusion?

1994 • 25 citations

Zona pellucida-mediated signal transduction in mammalian spermatozoa.

1990 • 25 citations

Use of a specific zona pellucida (ZP) protein 3 antiserum as a clinical marker for human ZP integrity and function

1996 • 24 citations

Analysis of an epitope sequence recognized by a monoclonal antibody MAb-5H4 against a porcine zona pellucida glycoprotein (pZP4) that blocks fertilization

1995 • 22 citations

Molecular Changes in the Human Zona Pellucida Associated with Fertilization and Human Spermzona Interactions ^a

1988 • 21 citations