Liposome-mediated gene transfer

The Fluid Mosaic Model of the Structure of Cell Membranes

1972 • 8,835 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Diffusion of univalent ions across the lamellae of swollen phospholipids

1965 • 4,347 citations

Cell Biology: a Laboratory Handbook

1995 • 1,226 citations

Cationic liposome-mediated transfection

1989 • 974 citations

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

1993 • 888 citations

Specific Recognition of Cruciform DNA by Nuclear Protein HMG1

1989 • 596 citations

Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.

1993 • 525 citations

Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

1993 • 459 citations

Increased Expression of DNA Cointroduced with Nuclear Protein in Adult Rat Liver

1989 • 459 citations

Specific interaction between Lex and Lex Determinants

1989 • 450 citations

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

1993 • 439 citations

Paramyxovirus Fusion: A Hypothesis for Changes

1993 • 417 citations

Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

1993 • 400 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.

1994 • 290 citations

pH-sensitive liposomes: acid-induced liposome fusion.

1984 • 283 citations

Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme.

1994 • 213 citations

Aerosol and intravenous transfection of human alpha 1-antitrypsin gene to lungs of rabbits.

1994 • 179 citations

Safety and Short-Term Toxicity of a Novel Cationic Lipid Formulation for Human Gene Therapy

1993 • 171 citations

An improved large scale fractionation of high mobility group non-histone chromatin proteins

1975 • 171 citations

Liposomes as Gene Carriers: Efficient Transformation of Mouse L Cells by Thymidine Kinase Gene

1982 • 157 citations

Expression of hepatitis B virus surface antigen in adult rat liver. Co-introduction of DNA and nuclear protein by a simplified liposome method

1991 • 145 citations

Introduction and Expression of the Human Insulin Gene in Adult Rat Liver

1989 • 140 citations

Liposomes as agents of DNA transfer

1993 • 133 citations

Direct in vivo gene introduction into rat kidney

1992 • 133 citations

Novel and effective gene transfer technique for study of vascular renin angiotensin system.

1993 • 106 citations

Growth inhibition of glioma cells transfected with the human beta-interferon gene by liposomes coupled with a monoclonal antibody.

1990 • 101 citations

The improved efficient method for introducing macromolecules into cells using HVJ (Sendai virus) liposomes with gangliosides

1987 • 100 citations

Use of the rabbit ear artery to serially assess foreign protein secretion after site-specific arterial gene transfer in vivo. Evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene expression.

1994 • 93 citations

Association of poly(CA)⋅Poly(TG) DNA Fragments into Four-Stranded Complexes Bound by HMG1 and 2

1994 • 92 citations

Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats.

1991 • 60 citations

Hypertensive rats produced by in vivo introduction of the human renin gene.

1993 • 44 citations

Molecular complementation of a collagen mutation in mammalian cells using yeast artificial chromosomes.

1992 • 43 citations

Novel liposomes for efficient transfection of .BETA.-galactosidase gene into COS-1 cells.

1989 • 39 citations

Monoclonal antibody against non-histone chromosomal protein high mobility group 1 Co-migrates with high mobility group 1 into the nucleus.

1986 • 38 citations

Liposomes as carriers for polypeptides

1989 • 33 citations