Complement C5b-9-Mediated Arachidonic Acid Metabolism in Glomerular Epithelial Cells

Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2

1996 • 1,987 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis

1999 • 1,488 citations

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

1995 • 1,102 citations

Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II

1995 • 985 citations

Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.

1994 • 862 citations

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

1994 • 826 citations

Cloning Two Isoforms of Rat Cyclooxygenase: Differential Regulation of Their Expression

1993 • 457 citations

Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

1997 • 427 citations

Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: implication for renal function

1997 • 368 citations

Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways

1999 • 350 citations

Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system

1994 • 339 citations

A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals

1997 • 284 citations

Transcriptional Regulation of Prostaglandin Synthase 2 Gene Expression by Platelet-derived Growth Factor and Serum

1996 • 244 citations

Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages.

1994 • 243 citations

Immunohistochemical localization of the prostaglandin-forming cyclooxygenase in renal cortex

1978 • 232 citations

Interleukin-1β-induced Cyclooxygenase-2 Expression Requires Activation of Both c-Jun NH2-terminal Kinase and p38 MAPK Signal Pathways in Rat Renal Mesangial Cells

1998 • 232 citations

Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activation.

1997 • 227 citations

Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells.

1994 • 219 citations

Functional coupling between secretory phospholipase A₂and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A₂

1998 • 178 citations

Characterization and hormonal regulation of the promoter of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. Identification of functional and protein-binding regions

1993 • 177 citations

[38] Experimental glomerulonephritis

1988 • 170 citations

Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.

1995 • 144 citations

Role of abnormally high transmural pressure in the permselectivity defect of glomerular capillary wall: a study in early passive Heymann nephritis.

1987 • 138 citations

Differentiation of Monocytoid THP-1 Cells with Phorbol Ester Induces Expression of Prostaglandin Endoperoxide Synthase-1 (COX-1)

1993 • 130 citations

Purification and Characterization of Prostaglandin H Synthase-2 from Sheep Placental Cotyledons

1995 • 119 citations

Cloning and Expression of Rat Prostaglandin Endoperoxide Synthase (Cyclooxygenase)-2 cDNA

1993 • 110 citations

Heymann nephritis: Mechanisms of renal injury

1989 • 105 citations

Modulation of eicosanoid metabolism in endothelial cells in a xenograft model. Role of cyclooxygenase-2.

1997 • 91 citations

Pathogenesis of glomerulonephritis.

1993 • 86 citations

Expression and localization of cyclooxygenase isoforms and cytosolic phospholipase A2 in anti-Thy-1 glomerulonephritis.

1998 • 60 citations

Cyclooxygenase metabolites mediate glomerular monocyte chemoattractant protein-1 formation and monocyte recruitment in experimental glomerulonephritis

1999 • 60 citations

Alternate COX-2 Transcripts Are Differentially Regulated: Implications for Post-Transcriptional Control

1997 • 57 citations

Complement C5b-9 complex activates phospholipases in glomerular epithelial cells

1989 • 55 citations

Indomethacin reduces proteinuria in passive Heymann nephritis in rats

1987 • 55 citations

Complement activates phospholipases and protein kinases in glomerular epithelial cells

1998 • 52 citations

A role for thromboxane in complement-mediated glomerular injury.

1987 • 49 citations

Effect of flosulide, a selective cyclooxygenase 2 inhibitor, on passive Heymann nephritis in the rat

1999 • 49 citations

Cyclooxygenase-1 Behaves as a Delayed Response Gene in PC12 Cells Differentiated by Nerve Growth Factor

1997 • 48 citations

Complement-induced phospholipase A2 activation in experimental membranous nephropathy1 See Editorial by Shankland, p. 1204.

2000 • 48 citations

Complement C5b-9 activates cytosolic phospholipase A2 in glomerular epithelial cells

1995 • 46 citations

Activation of phospholipase A2 by complement C5b-9 in glomerular epithelial cells.

1997 • 41 citations

An evaluation of the development of experimental membranous nephropathy

1987 • 33 citations

Fish oil has protective and therapeutic effects on proteinuria in passive Heymann nephritis

1993 • 30 citations

Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats

1996 • 21 citations