The Arginine Biosynthetic System and Its Regulation

Genetic regulatory mechanisms in the synthesis of proteins

1961 • 6,378 citations

ACETYLORNITHINASE OF ESCHERICHIA COLI: PARTIAL PURIFICATION AND SOME PROPERTIES

1956 • 4,156 citations

The Chemical Basis of Heredity

1957 • 1,044 citations

Evolving Genes and Proteins

1965 • 802 citations

ISOLATION OF THE LAC REPRESSOR

1966 • 657 citations

Control of Specific Gene Expression in Higher Organisms

1969 • 544 citations

Informational Macromolecules

1962 • 368 citations

The lac operator is DNA.

1967 • 303 citations

On the release of the formyl group from nascent protein

1968 • 290 citations

Histidine regulatory mutants in Salmonella typhimurium

1966 • 247 citations

Organizational Biosynthesis

1967 • 231 citations

CONTROL OF ISOLEUCINE, VALINE, AND LEUCINE BIOSYNTHESIS, I. MULTI-VALENT REPRESSION

1962 • 198 citations

COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE

1959 • 197 citations

TOPOGRAPHY OF COTRANSDUCIBLE ARGININE MUTATIONS IN ESCHERICHIA COLI K-12

1965 • 190 citations

Histidine regulatory mutants in Salmonella typhimurium

1966 • 164 citations

Studies on Repression of Arginine Biosynthesis in Escherichia coli

1961 • 163 citations

Effect of α-methylhistidine on the control of histidine synthesis

1964 • 143 citations

Genetics of Regulation of Enzyme Synthesis in the Arginine Biosynthetic Pathway of Escherichia coli

1961 • 140 citations

Histidine regulatory mutants in Salmonella typhimurium

1966 • 137 citations

Regulation of Protein Synthesis

1967 • 133 citations

Fine Structure Mapping by Complete Transduction Between Histidine-requiring Salmonella Mutants

1960 • 124 citations

Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli

1964 • 123 citations

Control mechanisms in cellular processes

2011 • 119 citations

Current linkage map of Escherichia coli.

1970 • 116 citations

ROLE OF VALYL-sRNA SYNTHETASE IN ENZYME REPRESSION

1965 • 107 citations

A unitary account of the repression mechanism of arginine biosynthesis in Escherichia coli

1969 • 88 citations

Translational Control of Gene Expression

1966 • 86 citations

Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium : Isolation of Regulatory Mutants

1969 • 84 citations

SPECIFIC BINDING OF LEUCYL TRANSFER RNA TO AN IMMATURE FORM OF L-THREONINE DEAMINASE: ITS IMPLICATIONS IN REPRESSION

1970 • 82 citations

Complementation Mapping by Abortive Transduction of Histidine requiring Salmonella Mutants

1960 • 80 citations

COMPLEMENTATION OF NONCHEMOTACTIC MUTANTS OF ESCHERICHIA COLI

1969 • 79 citations

Path of Ornithine Synthesis in Escherichia Coli

1953 • 79 citations

Acetylornithine δ-Transaminase

1964 • 78 citations

Feedback inhibition of acetylglutamate synthetase by arginine in Escherichia coli

1963 • 77 citations

THE CONTROL OF THE FORMATION OF SPECIFIC PROTEINS IN BACTERIA AND IN ANIMAL CELLS

1960 • 67 citations

Aspects of Repression in the Regulation of Enzyme Synthesis: Pathway-Wide Control and Enzyme-Specific Response

1961 • 67 citations

Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli

1968 • 66 citations

STUDIES ON REPRESSION OF THE HISTIDINE OPERON, II. THE ROLE OF THE FIRST ENZYME IN CONTROL OF THE HISTIDINE SYSTEM

1969 • 60 citations

The dual genetic control of ornithine transcarbamylase synthesis in Escherichia coli K12

1967 • 60 citations

Studies on the mechanism of repression of arginine biosynthesis in Escherichia coli

1964 • 57 citations

Conformational studies on modified proteins and peptides. II. Conformation of peptides with intact and overlapping helices obtained by cleavage of myoglobin at proline peptide bonds

1970 • 56 citations

Repression of the Histidine Operon: Effect of the First Enzyme on the Kinetics of Repression

1969 • 53 citations

Acetylation of Glutamic Acid by Extracts of Escherichia Coli

1953 • 52 citations

Evidence That Tryptophanyl Transfer Ribonucleic Acid Is Not the Corepressor of the Tryptophan Operon of Escherichia coli

1971 • 51 citations

REPRESSED AND INDUCED ENZYME FORMATION: A UNIFIED HYPOTHESIS

1957 • 51 citations

Tryptophan messenger translation in Escherichia coli

1970 • 48 citations

TRYPTOPHANYL TRANSFER RNA SYNTHETASE AND EXPRESSION OF THE TRYPTOPHAN OPERON IN THE trpS MUTANTS OF ESCHERICHIA COLI

1969 • 48 citations

N-acetyl-γ-glutamokinase and N-acetylglutamic γ-semialdehyde dehydrogenase: Repressible enzymes of arginine synthesis in Escherichiacoli

1962 • 47 citations

INDUCTION BY ARGININE OF ENZYMES OF ARGININE BIOSYNTHESIS IN ESCHERICHIA COLI B

1961 • 44 citations

Enzymic basis for a genetic suppression: Accumulation and deacylation of N-acetylglutamic γ-semialdehyde in enterobacterial mutants

1968 • 43 citations

Isolation of the novel regulatory mutants of the tryptophan biosynthetic system in Escherichia coli

1968 • 40 citations

Transfer RNA and the Control of the Histidine Operon

1966 • 40 citations

On the functional organization of the arg ECBH cluster of genes in Escherichia coli K-12

1969 • 39 citations

Translational Repression in the Arginine System of Escherichia coli

1970 • 39 citations

Amidohydrolase activity of Escherichia coli extracts with formylated amino acids and dipeptides as substrates

1967 • 39 citations

Individually repressible enzymes specified by clustered genes of arginine synthesis.

1965 • 38 citations

Regulation at the level of translation in the arginine pathway of Escherichia coli K12

1970 • 37 citations

Purification of ornithine transcarbamylase from derepressed cells of Escherichia coli W

1962 • 35 citations

A new regulatory gene for the tryptophan operon of Escherichiacoli

1967 • 31 citations

Isolation of the Arginine Repressor in Escherichia coli

1970 • 30 citations

Revised linkage map of Salmonella typhimurium.

1967 • 29 citations

On ornithine and proline synthesis in Escherichia coli

1953 • 29 citations

Temperature-sensitive Repression of the Tryptophan Operon in Escherichia coli

1969 • 28 citations

A unitary account of the repression mechanism of arginine biosynthesis in Escherichia coli

1969 • 27 citations

A Regulatory Gene Simultaneously Involved in Repression and Induction

1963 • 24 citations

Acetylhistidine as substrate for acetylornithinase: A new system for the selection of arginine regulation mutants in Escherichia coli

1970 • 21 citations

Electron transport reversal and steroid 11β-hydroxylation in adrenal cortical mitochondria

1970 • 20 citations

Transductional Analysis of Arginineless Mutants in Proteus mirabilis

1968 • 19 citations

Roles of Arginine and Canavanine in the Synthesis and Repression of Ornithine Transcarbamylase by Escherichia coli

1968 • 19 citations

REPRESSION OF AN ACETYLORNITHINE PERMEATION SYSTEM

1960 • 19 citations

REPRESSION-DEPENDENT ALTERATION OF AN ARGININE ENZYME IN Escherichia coli

1969 • 15 citations

Expression of the Arginine Regulon of Escherichia coli W: Evidence for a Second Regulatory Gene

1969 • 14 citations

Gene aggregation: evidence for a coming together of functionally related, not closely linked genes.

1966 • 13 citations

Isolation and Characterization of Arginine-inducible Acetylornithine δ-Transaminase from Escherichia coli

1970 • 13 citations

Repression by arginine in Escherichia coli: A comparison of arginyl transfer RNA profiles

1969 • 10 citations

Induction by an enzyme repressor in “nonrepressible” strains

1961 • 8 citations

Response of argr− spheroplasts of Escherichia coli to extracted arginine repressor

1970 • 6 citations

Onset of repression and derepression in arginine path of bacillus subtilis: A delayed-action “switch”

1965 • 6 citations

ENZYME REPRESSIBILITY AND REPRESSOR EFFECTIVENESS IN PHENOTYPIC REVERTANTS OF ARGININE AUXOTROPHS

1969 • 4 citations