Dictyostelium discoideum

Cryo-electron microscopy of vitrified specimens

1988 • 2,252 citations

Three-Dimensional Electron Microscopy of Macromolecular Assemblies

2006 • 1,113 citations

Adhesion of cells to surfaces coated with polylysine. Applications to electron microscopy.

1975 • 853 citations

Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography

2002 • 835 citations

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

2004 • 493 citations

Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity

2001 • 482 citations

Correlative microscopy: Bridging the gap between fluorescence light microscopy and cryo-electron tomography

2007 • 369 citations

Snapshots of nuclear pore complexes in action captured by cryo-electron tomography

2007 • 348 citations

Biochemical and structural studies of actomyosin-like proteins from non-muscle cells

1974 • 230 citations

Eat, kill or die: when amoeba meets bacteria

2008 • 229 citations

Distinct Functions of Nucleotide-Binding/Hydrolysis Sites in the Four AAA Modules of Cytoplasmic Dynein

2004 • 220 citations

Cryo‐fluorescence microscopy facilitates correlations between light and cryo‐electron microscopy and reduces the rate of photobleaching

2007 • 216 citations

AAA+ Ring and Linker Swing Mechanism in the Dynein Motor

2009 • 216 citations

Preparation of macromolecular complexes for cryo-electron microscopy

2007 • 213 citations

Infection by Tubercular Mycobacteria Is Spread by Nonlytic Ejection from Their Amoeba Hosts

2009 • 210 citations

Electron cryotomography sample preparation using the Vitrobot

2006 • 200 citations

Immune-like Phagocyte Activity in the Social Amoeba

2007 • 199 citations

PLA2 and PI3K/PTEN Pathways Act in Parallel to Mediate Chemotaxis

2007 • 196 citations

Dictyostelium discoideum: a new host model system for intracellular pathogens of the genus Legionella

2000 • 196 citations

Osmium ferricyanide fixation improves microfilament preservation and membrane visualization in a variety of animal cell types

1984 • 195 citations

Dictyostelium discoideum chemotaxis: Threshold for directed motion

2006 • 189 citations

Organization of Actin Networks in Intact Filopodia

2007 • 173 citations

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

2009 • 172 citations

Biochemical and Structural Studies of Actomyosin-like Proteins from Non-Muscle Cells

1974 • 168 citations

Moving EM: the Rapid Transfer System as a new tool for correlative light and electron microscopy and high throughput for high‐pressure freezing

2008 • 164 citations

ATP hydrolysis cycle–dependent tail motions in cytoplasmic dynein

2005 • 158 citations

Visualization of actin fibers associated with the cell membrane in amoebae of Dictyostelium discoideum.

1975 • 151 citations

Dictyostelium discoideum—a model for many reasons

2009 • 149 citations

Dictyostelium as host model for pathogenesis

2005 • 141 citations

Adherens junctions and β-catenin-mediated cell signalling in a non-metazoan organism

2000 • 138 citations

Structural characterization of a dynein motor domain

1998 • 132 citations

Tools for correlative cryo-fluorescence microscopy and cryo-electron tomography applied to whole mitochondria in human endothelial cells

2009 • 129 citations

Electron microscopic mapping of monoclonal antibodies on the tail region of Dictyostelium myosin

1982 • 126 citations

Towards a molecular understanding of human diseases using Dictyostelium discoideum

2006 • 124 citations

Spindle and kinetochore morphology of Dictyostelium discoideum.

1976 • 120 citations

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function.

1987 • 118 citations

Concatenated metallothionein as a clonable gold label for electron microscopy

2007 • 115 citations

A review of high‐pressure freezing preparation techniques for correlative light and electron microscopy of the same cells and tissues

2009 • 114 citations

Cryo-electron tomography of cells: connecting structure and function

2008 • 105 citations

Dictyostelium Sun‐1 Connects the Centrosome to Chromatin and Ensures Genome Stability

2008 • 104 citations

A membrane cytoskeleton from Dictyostelium discoideum. I. Identification and partial characterization of an actin-binding activity.

1981 • 100 citations

Ethane-Freezing/Methanol-Fixation of Cell Monolayers: A Procedure for Improved Preservation of Structure and Antigenicity for Light and Electron Microscopies

1998 • 99 citations

Visualization of proteins in intact cells with a clonable tag for electron microscopy

2008 • 96 citations

Overexpression of cytoplasmic dynein's globular head causes a collapse of the interphase microtubule network in Dictyostelium.

1996 • 95 citations

A Single-headed Recombinant Fragment of Dictyostelium Cytoplasmic Dynein Can Drive the Robust Sliding of Microtubules

2004 • 92 citations

Chapter 6 Phagocytosis and Host–Pathogen Interactions in Dictyostelium with a Look at Macrophages

2008 • 89 citations

Architecture of the microtubule component of mitotic spindles from Dictyostelium discoideum

1985 • 86 citations

DictyosteliumLIS1 Is a Centrosomal Protein Required for Microtubule/Cell Cortex Interactions, Nucleus/Centrosome Linkage, and Actin Dynamics

2005 • 84 citations

Navigating signaling networks: chemotaxis in Dictyostelium discoideum

2006 • 80 citations

Probing the macromolecular organization of cells by electron tomography

2009 • 79 citations

25Å Resolution Structure of a Cytoplasmic Dynein Motor Reveals a Seven-member Planar Ring

2004 • 79 citations

Expression and Characterization of a Functional Myosin Head Fragment in Dictyostelium discoideum

1989 • 76 citations

Optimized Fixation and Immunofluorescence Staining Methods for <i>Dictyostelium</i> Cells

2006 • 73 citations

Studying intracellular transport using high-pressure freezing and Correlative Light Electron Microscopy

2009 • 72 citations

Dictyostelium discoideum Protocols

2013 • 70 citations

Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium

2008 • 69 citations

Flow Photolysis for Spatiotemporal Stimulation of Single Cells

2007 • 66 citations

Three-dimensional structure of cytoplasmic dynein bound to microtubules

2007 • 66 citations

Unusual Centrosome Cycle inDictyostelium: Correlation of Dynamic Behavior and Structural Changes

1999 • 64 citations

Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity

2001 • 64 citations

Morphology and fine structure of the slime mold Dictyostelium discoideum

1957 • 61 citations

Unravelling the structure of the lamellipodium

2008 • 59 citations

Mitosis in the cellular slime mold Polysphondylium violaceum.

1975 • 58 citations

Dictyostelium MTOC: Structure and linkage to the nucleus

1985 • 57 citations

An actin-like protein from amoebae of Dictyostelium discoideum

1972 • 56 citations

Site-specific inhibition of myosin-mediated motility in vitro by monoclonal antibodies.

1985 • 55 citations

A membrane cytoskeleton from Dictyostelium discoideum. II. Integral proteins mediate the binding of plasma membranes to F-actin affinity beads.

1984 • 55 citations

dictyostelium γ-tubulin: molecular characterization and ultrastructural localization

1998 • 50 citations

A Genetically Encoded Metallothionein Tag Enabling Efficient Protein Detection by Electron Microscopy

2007 • 48 citations

In vitro nucleation of microtubules from microtubule‐organizing center prepared from cellular slime mold

1982 • 47 citations

Dictyostelium Sun1 is a dynamic membrane protein of both nuclear membranes and required for centrosomal association with clustered centromeres

2009 • 41 citations

Unprecedented, Low Cytotoxicity of Spongelike Calcium Phosphate/Poly(ethylene imine) Hydrogel Composites

2008 • 35 citations

Formation of multivesicular endosomes in Dictyostelium

2004 • 29 citations

An Elmo-like Protein Associated with Myosin II Restricts Spurious F-Actin Events to Coordinate Phagocytosis and Chemotaxis

2008 • 29 citations

Molecular analysis of the cytosolic Dictyostelium γ-tubulin complex

2002 • 28 citations

Dictyostelium discoideum Protocols

2006 • 26 citations

Spatiotemporal Regulation of Ras-GTPases During Chemotaxis

2009 • 24 citations

Yersinia outer protein YopE affects the actin cytoskeleton in Dictyostelium discoideumthrough targeting of multiple Rho family GTPases

2009 • 20 citations

A Flexible Linkage Between the Dynein Motor and its Cargo

2006 • 18 citations

Chapter 10 Ultrastructural Localization of Cytoskeletal Proteins in Dictyostelium Amoebae

1987 • 18 citations

Chapter 15 Probing the Mechanisms of Mitosis with Dictyostelium discoideum

1987 • 17 citations

Electron microscopic analysis of a fusion protein of postsynaptic density-95 and metallothionein in cultured hippocampal neurons

2007 • 15 citations

Isolation of centrosomes from dictyostelium

2001 • 15 citations

Molecular Determination by Electron Microscopy of the Dynein–Microtubule Complex Structure

2007 • 7 citations

Preparation of Dictyostelium discoideum for electron microscopy.

1984 • 7 citations

Techniques for the visualisation of cytoskeletal components in Dictyostelium discoideum

1991 • 6 citations

Cryofixation Methods for Ultrastructural Studies of <i>Dictyostelium discoideum</i>

2006 • 5 citations

Temperature dependence of myosin-II tail fragment assembly

2008 • 1 citations