Biologically Active Peptides in the Mammalian Central Nervous System

Identification of two related pentapeptides from the brain with potent opiate agonist activity

1975 • 3,780 citations

Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone

1973 • 3,509 citations

Isolated removal of hypothalamic or other brain nuclei of the rat

1973 • 1,421 citations

SALMONELLAS IN MEAT.

1964 • 1,158 citations

Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence

1976 • 1,025 citations

On some physiological actions of ergot

1906 • 980 citations

NEURAL CONTROL OF THE PITUITARY GLAND

1948 • 909 citations

New peptide in the vertebrate CNS reacting with antigastrin antibodies

1975 • 749 citations

Observations with differential stains on human islets of langerhans.

1941 • 639 citations

The Regional Distribution of Somatostatin in the Rat Brain

1975 • 594 citations

EFFECTS OF THYROTROPIN-RELEASING HORMONE IN DEPRESSION*1

1972 • 558 citations

THE SYNTHESIS OF AN OCTAPEPTIDE AMIDE WITH THE HORMONAL ACTIVITY OF OXYTOCIN

1953 • 558 citations

Induction of Mating Behavior in Rats by Luteinizing Hormone-Releasing Factor

1973 • 533 citations

The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide

1969 • 530 citations

HYPOTHALAMIC CONTROL OF THE ANTERIOR PITUITARY

1963 • 483 citations

Thyrotropin-Releasing Hormone (TRH): Distribution in Hypothalamic and Extrahypothalamic Brain Tissues of Mammalian and Submammalian Chordates

1974 • 473 citations

CELLULAR LOCALIZATION OF SOMATOSTATIN IN ENDOCRINE-LIKE CELLS AND NEURONS OF THE RAT WITH SPECIAL REFERENCES TO THE A1-CELLS OF THE PANCREATIC ISLETS AND TO THE HYPOTHALAMUS

1975 • 455 citations

Frontiers in Neuroendocrinology

1975 • 431 citations

Distribution of thyroptropin-releasing hormone (TRH) in the central nervous system as revealed with immunohistochemistry

1975 • 425 citations

Thyrotropin-Releasing Hormone: Regional Distribution in Rat Brain

1974 • 421 citations

Regional distribution of substance P in the brain of the rat

1976 • 417 citations

Hormone Secretion of the Anterior Pituitary Gland After Physical Interruption of All Nervous Pathways to the Hypophysiotrophic Area

1965 • 397 citations

Thyrotropin-Releasing Hormone in Specific Nuclei of Rat Brain

1974 • 378 citations

IMPROVEMENT IN MENTAL DEPRESSION WITH DECREASED THYROTROPIN RESPONSE AFTER ADMINISTRATION OF THYROTROPIN-RELEASING HORMONE

1972 • 374 citations

Brain-endocrine interaction

1972 • 365 citations

HUMORAL HYPOTHALAMIC CONTROL OF ANTERIOR PITUITARY: A STUDY WITH COMBINED TISSUECULTURES

1955 • 365 citations

Neural crest origin of the endocrine polypeptide (APUD) cells of the gastrointestinal tract and pancreas

1971 • 361 citations

The permeability of the hypophysis and hypothalamus to vital dyes, with a study of the hypophyseal vascular supply

1936 • 358 citations

On the Physiological Action of Extracts of Pituitary Body and certain other Glandular Organs

1895 • 357 citations

THE DISABILITIES CAUSED BY HYPOPHYSECTOMY AND THEIR REPAIR

1927 • 345 citations

Das Zwischenhirn-Hypophysensystem

1954 • 319 citations

Über die Funktion der Hypophyse

1912 • 305 citations

Distribution and Concentration of TRH in the Rat Brain¹²

1974 • 300 citations

Die Lichtempfindlichkeit Blinder Elritzen. (Untersuchungen �ber das Zwischenhirn der Fische I.)

1928 • 298 citations

Effects of Somatostatin on the Secretion of Thyrotropin and Prolactin

1974 • 297 citations

LRF producing cells of the mammalian hypothalamus

1973 • 297 citations

Thyrotropin Releasing Hormone: Enhancement of Dopa Activity by a Hypothalamic Hormone

1972 • 283 citations

Neural Control of the Pituitary Gland

1956 • 278 citations

Isolation and Amino-acid Sequence of β-LPH from Sheep Pituitary Glands

1965 • 273 citations

ENZYMATIC CLEAVAGE OF GLYCINAMIDE FROM VASOPRESSIN AND A PROPOSED STRUCTURE FOR THIS PRESSOR-ANTIDIURETIC HORMONE OF THE POSTERIOR PITUITARY

1953 • 269 citations

Frontiers in neurology and neuroscience research

1973 • 263 citations

Structure of the porcine LH- and FSH-releasing hormone. II. Confirmation of the proposed structure by conventional sequential analyses

1971 • 245 citations

Anatomical Neuroendocrinology

1978 • 242 citations

Carnosine in the Primary Olfactory Pathway

1974 • 239 citations

EXPERIMENTAL DIABETES INSIPIDUS

1921 • 235 citations

Thyrotropin releasing hormone (TRH)-containing nerve terminals in certain brain stem nuclei and in the spinal cord

1975 • 234 citations

STIMULATION OF THE RELEASE OF CORTICOTROPIN FROM THE ADENOHYPOPHYSIS BY A NEUROHYPOPHYSIAL FACTOR¹

1955 • 223 citations

Hypothalamic Control of the Anterior Pituitary

1969 • 221 citations

Thyrotrophic Hormone Secretion in Rats After Partial or Total Interruption of Neural Aiferents to the Medial Basal Hypothalamus

1967 • 219 citations

A Portal Circulation from the Pituitary to the Hypothalamic Region.

1930 • 216 citations

Thyrotropin releasing hormone: Antagonism of pentobarbital in rodents

1974 • 213 citations

The Relationship Between Progestins and Gonadotropins During the Late Luteal Phase of the Menstrual Cycle in Rhesus Monkeys

1974 • 208 citations

Primary Structure of Somatostatin, A Hypothalamic Peptide That Inhibits the Secretion of Pituitary Growth Hormone

1973 • 203 citations

HYPOPHYSIOTROPHIC AREA IN THE HYPOTHALAMUS

1962 • 202 citations

LH-Releasing Activity in Hypothalamic Extracts

1960 • 193 citations

The use of mass spectrometry in deducing the sequence of somatostatin — A hypothalamic polypeptide that inhibits the secretion of growth hormone

1973 • 191 citations

Handbook of Physiology

1960 • 190 citations

Gonadotrophic Hormone Secretion in Female Rats After Partial or Total Interruption of Neural Afferents to the Medial Basal Hypothalamus

1967 • 188 citations

Antagonism of ethanol narcosis by thyrotropin releasing hormone

1974 • 170 citations

SOMATOSTATINERGIC NEURONS IN ANTERIOR HYPOTHALAMUS: IMMUNOHISTOCHEMICAL LOCALIZATION¹

1976 • 167 citations

Short History of Medicine

1962 • 162 citations

Studies of antidromically identified neurosecretory cells of the hypothalamus by intracellular and extracellular recordings

1972 • 157 citations

LH-RH-Containing Neural Elements in the Rat Hypothalamus¹

1975 • 149 citations

Luteinizing Hormone-Releasing Hormone (LH-RH) Content of the Hypothalamic Nuclei in Rat

1974 • 144 citations

Thyrotrophin-releasing hormone and shaking behaviour in rat

1975 • 143 citations

CENTRAL NERVOUS SYSTEM EFFECTS OF HYPOTHALAMIC PEPTIDES

1975 • 143 citations

Control of Ovulation

1978 • 142 citations

Neurosecretion

1966 • 141 citations

Electrical stimulation of the hypothalamus and the mechanism of neural control of the adenohypophysis

1948 • 139 citations

Ultrastructural localization of luteinizing hormone-releasing hormone in the median eminence of the rat

1975 • 138 citations

THE ISOLATION OF A PROTEIN FROM THE PARS NEURALIS OF THE OX PITUITARY WITH CONSTANT OXYTOCIC, PRESSOR AND DIURESIS-INHIBITING ACTIVITIES

1942 • 134 citations

Immunofluorescence Study of the Preoptico-Infundibular LRF Neurosecretory Pathway in the Normal, Castrated or Testosterone-Treated Male Guinea Pig

1974 • 132 citations

The induction of ovulation in the rabbit, by electrical stimulation of the hypothalamo-hypophysial mechanism

1937 • 130 citations

Electron microscopic immunohistochemical localization of growth hormone‐release inhibiting hormone (somatostatin) in the rat median eminence

1974 • 130 citations

Localization of Luteinizing Hormone-Releasing Hormone in the Preoptic Area and Hypothalamus of the Rat Using Radioimmunoassay

1975 • 127 citations

TRF and Thyroid Hormones on Prolactin Secretion By Rat Anterior Pituitary Cellsin Vitro1

1973 • 125 citations

The American Physiological Society

1916 • 119 citations

TRH: a possible mediator of thermoregulation

1974 • 115 citations

Releasing Factors in the Circumventricular Organs of the Rat Rrain

1976 • 114 citations

THYROTROPHIN-RELEASING HORMONE IN THE TREATMENT OF DEPRESSION

1974 • 109 citations

IMPROVEMENT IN MENTAL DEPRESSION WITH DECREASED THYROTROPIN RESPONSE AFTER ADMINISTRATION OF THYROTROPIN-RELEASING HORMONE

1972 • 106 citations

Adrenocorticotrophic Hormone Secretion in Rats after Partial or Total Deafferentation of the Medial Basal Hypothalamus

1967 • 104 citations

Immunohistochemical Localization of Luteinizing Hormone-Releasing Hormone in the Rat Median Eminence

1974 • 104 citations

Transport of LRF from CSF to Hypophysial Portal and Systemic Blood and the Release of LH¹

1974 • 101 citations

Oestrous rhythm. Pseudopregnancy and the pituitary stalk in the rat

1950 • 101 citations

Localization of growth hormone‐release‐inhibiting hormone (somatostatin) in the rat brain

1975 • 100 citations

Immunoreactive LH-RH neurons in the hypothalamus identified by light and fluorescent microscopy

1975 • 98 citations

Action of Luteinizing Hormone-Releasing Factor (LRF) in the Initiation of Lordosis Behavior in the Estrone-Primed Ovariectomized Female Rat

1975 • 98 citations

Pituitary hormone releasing or inhibiting activity of metal ions present in hypothalamic extracts

1973 • 95 citations

THE DISTRIBUTION OF NEUROPHYSIN‐SECRETING PATHWAYS IN THE MAMMALIAN BRAIN: LIGHT MICROSCOPIC STUDIES USING THE IMMUNOPEROXIDASE TECHNIQUE*

1975 • 92 citations

A hypothalamic luteinizing-hormone-releasing factor

1962 • 92 citations

TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats

1974 • 88 citations

A SHORT HISTORY OF MEDICINE

1929 • 83 citations

ACTIVATION OF THE ANTERIOR HYPOPHYSIS BY ELECTRICAL STIMULATION IN THE RABBIT1

1946 • 79 citations

Luteinizing hormone ?Releasing hormone (LH-RH) pathway of the rat hypothalamus revealed by the unlabeled antibody peroxidase-antiperoxidase method

1974 • 79 citations

NEURAL CONTROL OF THE PITUITARY

1956 • 77 citations

EXPERIMENTAL RESEARCHES ON THE PITUITARY BODY DIABETES INSIPIDUS, GLYCOSURIA AND THOSE DYSTROPHIES CONSIDERED AS HYPOPHYSEAL IN ORIGIN*

1920 • 76 citations

Localization of luteinizing hormone‐releasing hormone in the mammalian hypothalamus

1974 • 73 citations

Immunocytochemical Localization of LHRH in Axons and Nerve Terminals of the Rat Median Eminence

1974 • 72 citations

Neural Control of Anterior Pituitary Functions

1968 • 71 citations

Ovulation in Persistent-Estrous Rats after Electrical Stimulation of the Brain.

1957 • 70 citations

Amino acid sequence of porcine β-lipotropic hormone

1971 • 70 citations

Complete amino acid sequence of bovine neurophysin II

1971 • 69 citations

Ovulation Induced by Hypothalamic Stimulation in the Anesthetized Rat

1958 • 67 citations

Proceedings of the First Clinical ACTH Conference

1951 • 64 citations

Vasopressin and oxytocin in the mammalian hypothalamus

1961 • 63 citations

Effect of hypothalamic deafferentation on thyrotropin-releasing hormone levels in rat brain.

1975 • 62 citations

Localization of vasopressin in discrete areas of the rat hypothalamus

1975 • 62 citations

EFFECT OF PLASMA FROM HYPOPHYSEAL-PORTAL VESSEL BLOOD ON ADRENAL ASCORBIC ACID1

1956 • 61 citations

Immuno-electron microscopic localization of luteinizing hormone-releasing hormone in the arcuate nuclei and median eminence of the rat

1975 • 61 citations

EVIDENCE OF HYPOTHALAMIC CONTROL OF HYPOPHYSEAL GONADOTROPIC FUNCTIONS IN THE FEMALE GUINEA PIG¹

1943 • 61 citations

A DOUBLE-BLIND CROSSOVER SEQUENTIAL TRIAL OF ORAL THYROTROPHIN-RELEASING HORMONE IN DEPRESSION

1974 • 60 citations

AN INVESTIGATION INTO THE FUNCTIONS OF THE PITUITARY AND THYROID GLANDS. PART. I. TECHNIQUE OF THEIR EXPERIMENTAL SURGERY AND SUMMARY OF RESULTS

1923 • 59 citations

The Effect of Surgical Isolation of the Hypothalamus on Its Luteinizing Hormone-Releasing Hormone Content

1976 • 56 citations

DIFFERENTIAL EFFECTS OF HYPOTHALAMIC DEAFFERENTATION UPON LUTEINIZING HORMONERELEASING HORMONE IN THE MEDIAN EMINENCE AND ORGANUM VASCULOSUM OF THE LAMINA TERMINALIS

1975 • 54 citations

Neurohypophysial Peptides in the Bovine Hypothalamus:The Relationship of Neurophysin I to Oxytocin, and Neurophysin II to Vasopressin in Supraoptic and Paraventrieular Regions

1974 • 54 citations

Some properties of antidromically activated units in the paraventricular nucleus of the hypothalamus

1970 • 54 citations

Somatostatin content of the hypothalamic ventromedial and arcuate nuclei and the circumventricular organs in the rat

1976 • 53 citations

Changes in Electrical Activity in the Rat Hypothalamus Related to Electrochemical Stimulation of Adenohypophyseal Function

1969 • 51 citations

Localization of FSH-Releasing Factor in the Hypothalamus and Neurohypophysis as Determined byin VitroAssay

1968 • 51 citations

Distribution of Releasing Factors, Biogenic Amines, and Related Enzymes in the Bovine Median Eminence

1976 • 49 citations

Die Lichtempfindlichkeit blinder Elritzen

1928 • 48 citations

THE EFFECT OF HYPOTHALAMIC LESIONS ON THYROID FUNCTION IN THE DOG¹²

1955 • 48 citations

Localization of LH-Releasing Factor in the Hypothalamus and Neurohypophysis as Determined by an in Vitro Method

1970 • 46 citations

Studies on the primary structure of human β‐lipotropic hormone

1972 • 45 citations

Neurohypophysis. Structure and Function

1968 • 45 citations

THYROID FUNCTION, BODY TEMPERATURE REGULATION AND GROWTH IN RATS WITH HYPOTHALAMIC LESIONS¹²

1960 • 44 citations

Localization of Thyrotropin-Releasing Factor (TRF) in the Hypothalamus of the Rat

1974 • 43 citations

RELEASE OF LUTEINIZING HORMONE FROM THE ANTERIOR HYPOPHYSIS BY AN ACETYLCHOLINE-LIKE SUBSTANCE FROM THE HYPOTHALAMIC REGION

1941 • 42 citations

THE PITUITARY-HYPOTHALAMIC MECHANISM: EXPERIMENTAL OCCLUSION OF THE PITUITARY STALK

1936 • 42 citations

Tremorogenic effect of thyrotropin releasing hormone in rats

1974 • 42 citations

Suprachiasmatic LH-Releasing Factor

1969 • 40 citations

The effect of pituitary stalk section on the adrenocortical response to stress in the rabbit

1957 • 40 citations

ALTERATIONS OF ADRENAL CORTICAL AND OVARIAN ACTIVITY FOLLOWING HYPOTHALAMIC LESIONS BASED ON EOSINOPHILE RESPONSE, HORMONE ASSAY AND HISTOLOGICAL EXAMINATION

1955 • 39 citations

THE RELATION OF THE NERVOUS SYSTEM TO OVULATION AND OTHER PHENOMENA OF THE FEMALE REPRODUCTIVE TRACT

1937 • 34 citations

PLASMA 17-HYDROXYCORTICOSTEROID RESPONSE TO HYPOTHALAMIC STIMULATION IN THE CONSCIOUS RHESUS MONKEY

1958 • 33 citations

Über Isolierte Beeinflussung des Gesamtstoffwechsels Vom zwischenhirn aus

1929 • 33 citations

Neurohypophyseal Hormones

1963 • 32 citations

Regeneration of the Hypophysial Portal Vessels

1949 • 31 citations

Regeneration of the Hypophysial Portal Vessels, after Section of the Hypophysial Stalk, in the Monkey (Macacus rhesus)

1950 • 31 citations

CYCLICAL PHENOMENA PRODUCED IN RATS BY SECTION OF THE PITUITARY STALK AND THEIR POSSIBLE RELATION TO PSEUDO-PREGNANCY

1933 • 30 citations

THE DISTRIBUTION OF OXYTOCIN AND VASOPRESSIN(ANTIDIURETIC HORMONE) IN THE NEUROHYPOPHYSIS OF THE CAMEL1

1956 • 29 citations

PITUITARY-THYROID FUNCTION IN RATS WITH HYPOTHALAMIC LESIONS11

1956 • 29 citations

Electrical Stimulation of the Hypothalamus: Simultaneous Effects on the Pituitary-Adrenal and Thyroid Systems of the Rat

1964 • 28 citations

EFFECT OF HYPOTHALAMIC AND BRAIN STEM STRUCTURE STIMULATION ON PITUITARY-ADRENOCORTICAL FUNCTION.

1963 • 28 citations

Oxytocin Content of Microdissected Areas of Rat Hypothalamus

1976 • 27 citations

Observations on Pituitary Transplants Into the Hypothalamus of the Rat

1965 • 27 citations

Immunofluorescence Mapping of Central Monoamine and Releasing Hormone (LRH) Systems1

2015 • 26 citations

Effect of a fraction of bovine hypothalamic extract on the release of TSH by rat adenohypophysesin vitro

1961 • 25 citations

THE HYPOTHALAMIC CONTROL OF THE THYROTROPHTHYROIDAL FUNCTION

1956 • 25 citations

Comparison of effect of environmental and preoptic cooling on plasma cortisol levels

1964 • 23 citations

Observations on the Morphology and Histochemistry of the Mouse Pituitary Implanted in the Anterior Eye Chamber

1956 • 23 citations

PRIMARY STRUCTURE AND EVOLUTION OF NEUROPHYSINS*

1975 • 21 citations

ENDOKRINOLOGISCHE UNTERSUCHUNGEN AN RATTEN MIT DURCHTRENNTEM HYPOPHYSENSTIEL

1938 • 21 citations

On the origin of luteinizing hormone-releasing hormone (LH-RH) in the supraoptic crest

1975 • 19 citations

Absence of Luteinizing Hormone-Releasing Hormone(LH-RH) from Catecholaminergic Neurons

1975 • 18 citations

THYROID RESPONSE TO PARTIAL THYROIDECTOMY, THYROXINE AND 2,4 DINITROPHENOL IN RATS WITH HYPOTHALAMIC LESIONS¹²

1960 • 17 citations

Proceedings of the First Clinical ACTH Conference

1951 • 13 citations

Growth of hypophysectomized rats bearing pituitary transplant in the hypothalamus.

1963 • 12 citations

Electrical Stimulation of the Hypothalamus and TSH Secretion in the Rat

1963 • 12 citations

[Influence of hypothalamus lesions on development of the body and various organs in newborn animals].

1957 • 8 citations

Hypothalamic Stimulation and Ascorbic Acid Content of Endocrine Glands of the Albino Rat.

1963 • 5 citations

Changes in the pituitarytaget gland system following electrolytic lesion of median eminence and hypophyseal stalk in male rats.

1963 • 1 citations