Cloned cytolytic T-effector cells and their malignant variants produce an extracellular matrix degrading trypsin-like serine proteinase.

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase

1984 • 344 citations

Stimulation of corneal endothelial cell proliferation in vitro by fibroblast and epidermal growth factors

1977 • 335 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

The role of proteinase in cellular invasiveness

1983 • 297 citations

Cytotoxic Effects of Antigen- and Mitogen-Induced T Cells on Various Targets

1975 • 224 citations

Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells.

1980 • 221 citations

Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes.

1985 • 210 citations

The production and localization of laminin in cultured vascular and corneal endothelial cells

1981 • 177 citations

Tumor invasion and host extracellular matrix

1983 • 176 citations

Thiobenzyl benzyloxycarbonyl-l-lysinate, substrate for a sensitive colorimetric assay for trypsin-like enzymes

1979 • 176 citations

Interaction of T lymphocytes and macrophages with cultured vascular endothelial cells: Attachment, invasion, and subsequent degradation of the subendothelial extracellular matrix

1984 • 133 citations

Stimulation of Mouse B Lymphocytes by Trypsin

1974 • 108 citations

Sequential degradation of heparan sulfate in the subendothelial extracellular matrix by highly metastatic lymphoma cells

1985 • 75 citations

A Cytotoxic Proteinase Isolated from Human Lymphocytes

1978 • 71 citations

Characterization and isolation of a trypsin-like serine protease from a long-term culture cytolytic T cell line and its expression by functionally distinct T cells.

1986 • 59 citations

Aged murine killer T-cell clones acquire specific cytotoxicity for P815 mastocytoma cells

1984 • 56 citations

Evidence that polymorphism in the murine major histocompatibility complex may be generated by the assortment of subgene sequences.

1985 • 55 citations

Quantitation of fibrinolytic activity of Syrian hamster fibroblasts using 3H-labeled fibrinogen prepared by reductive alkylation.

1977 • 31 citations

Inhibition of Lymphocyte Transformation: Effect of Soy Bean Trypsin Inhibitor and Synthetic Anti-Proteases

1975 • 31 citations

Modulation by α-2 Macroglobulin of Human Lymphocyte Proliferation in Response to Mitogens and Antigen

1976 • 29 citations

Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line

1985 • 27 citations

Detection and partial characterization of lymphoid cell surface proteases

1980 • 23 citations

Secretion of an articular cartilage proteoglycan-degrading enzyme activity by murine T lymphocytes in vitro.

1985 • 15 citations

Quantitative determination of disseminated tumor cells by [3H]thymidine incorporation in vitro and by agar colony formation.

1982 • 10 citations

The Change of Specificity, Karyotype, and Antigen-Receptor Gene Expression is Correlated in Cytotoxic T-Cell Lines

1986 • 5 citations

Immunoregulation by mouse T cell clones III. Cloned H‐Y‐specific cytotoxic T cells secrete a soluble mediator(s) that inhibits cytotoxic responses by acting on both Lyt‐2⁻ and L3T4⁻ lymphocytes

1985 • 3 citations