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Macronutrients and Cancer

Data up to Jan 2025

Published1984
Citations7
References162

Total Citations Per Year

Abstract

References (162)

Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices

1975 • 2,207 citations

Variations in mortality by weight among 750,000 men and women

1979 • 1,200 citations

A co-operative trial in the primary prevention of ischaemic heart disease using clofibrate. Report from the Committee of Principal Investigators.

1978 • 1,058 citations

Promoting Effect of Bile Acids on Colon Carcinogenesis After Intrarectal Instillation of N -Methyl- N ′ nitro- N -nitrosoguanidine in Rats 2

1974 • 717 citations

BACTERIA AND qTIOLOGY OF CANCER OF LARGE BOWEL

1971 • 641 citations

Role of life-style and dietary habits in risk of cancer among seventh-day adventists.

1975 • 588 citations

EFFECT OF CHOLESTEROL-LOWERING DIET ON MORTALITY FROM CORONARY HEART-DISEASE AND OTHER CAUSES

1972 • 497 citations

Large-Bowel Cancer in Hawaiian Japanese2

1973 • 492 citations

Environmental Factors and Cancer of the Colon and Breast

1973 • 448 citations

Diet in the Epidemiology of Cancer of the Colon and Rectum<xref ref-type="fn" rid="FN2">2</xref>

1978 • 423 citations

Large-Bowel Carcinogenesis: Fecal Constituents of Populations With Diverse Incidence Rates of Colon Cancer2

1973 • 413 citations

Stomach Cancer Among Japanese in Hawaii<xref ref-type="fn" rid="FN2">2</xref>

1972 • 388 citations

Experimental evidence of dietary factors and hormone-dependent cancers.

1975 • 379 citations

Dietary fat in relation to tumorigenesis.

1975 • 377 citations

ACUTE ANTERIOR UVEITIS AND HL-A 27

1974 • 366 citations

Progress in cancer research and therapy

1978 • 311 citations

Employer's liability for cancer of the scrotum

1968 • 309 citations

The Genesis and Growth of Tumors. III. Effects of a High-Fat Diet

1942 • 304 citations

Effects of level and type of dietary fat on incidence of mammary tumors induced in female sprague‐dawley rats by 7,12‐dimethylbenz(α) anthracene

1971 • 304 citations

A case‐control study of diet and colo‐rectal cancer

1980 • 303 citations

Cancer Incidence by Levels of Cholesterol

1981 • 285 citations

A CASE-CONTROL STUDY OF RELATIONSHIPS OF DIET AND OTHER TRAITS TO COLORECTAL CANCER IN AMERICAN BLACKS1

1979 • 278 citations

Metabolic epidemiology of large bowel cancer. Fecal bulk and constituents of high-risk North American and low-risk finnish population

1978 • 264 citations

Nutrition and its Relationship to Cancer

1980 • 256 citations

Induction of resistant hepatocytes as a new principle for a possible short-term in vivo test for carcinogens.

1980 • 243 citations

Trends in cancer incidence: Causes and practical implications

1983 • 242 citations

A STUDY OF DIET AND BREAST CANCER1

1978 • 237 citations

PLASMA LIPIDS AND MORTALITY: A SOURCE OF ERROR

1980 • 222 citations

INCIDENCE OF CANCER IN MEN ON A DIET HIGH IN POLYUNSATURATED FAT

1971 • 218 citations

Bacteria, Nitrosamines and Cancer of the Stomach

1973 • 214 citations

Nutrient intakes in relation to cancer incidence in Hawaii

1981 • 214 citations

A case-control study of large bowel cancer in Japan.

1980 • 214 citations

Etiological Factors in Gastrointestinal Cancer in Man<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1966 • 212 citations

COLON CANCER AND BLOOD-CHOLESTEROL

1974 • 210 citations

Breast cancer incidence and nutritional status with particular reference to body weight and height.

1975 • 205 citations

Breast-cancer incidence and mortality rates in different countries in relation to known risk factors and dietary practices

1979 • 197 citations

Dietary factors and breast cancer risk

1981 • 197 citations

Lasting Influence of Early Caloric Restriction on Prevalence of Neoplasms in the Rat<xref ref-type="fn" rid="FN1">2</xref>

1971 • 196 citations

Therapeutic Influence on the Prognosis of Ulcerative Colitis

1974 • 185 citations

The effect of bile on the induction of experimental intestinal tumors in rats

1974 • 180 citations

Epidemiologic studies of cancer of the stomach, colon, and rectum; with special emphasis on the role of diet.

1974 • 179 citations

The relationship of serum cholesterol to the incidence of cancer in Evans County, Georgia

1980 • 178 citations

LYMPHOCYTE RESPONSE

1974 • 176 citations

EPILEPTIC DEATH DUE TO SUFFOCATION DURING SLEEP

1970 • 174 citations

Effects of free fatty acids on the growth of normal and neoplastic rat mammary epithelial cells.

1979 • 169 citations

Diet and azo dye tumors; effect of diet during a period when the dye is not fed.

1949 • 166 citations

The genesis and growth of tumors; effects of varying the proportion of protein (casein) in the diet.

1949 • 164 citations

Promotion of azoxymethane-induced intestinal cancer by high-fat diet in rats.

1979 • 164 citations

Polyunsaturated fat, cholesterol and large bowel tumorigenesis

1977 • 160 citations

Dietary fibre and regional large-bowel cancer mortality in Britain

1979 • 155 citations

Effects of dietary constituents on the metabolism of chemical carcinogens.

1975 • 155 citations

SERUM CHOLESTEROL AND MORTALITY IN A JAPANESE-AMERICAN POPULATION

1981 • 152 citations

DIETARY CHOLESTEROL, FAT, AND FIBRE, AND COLON-CANCER MORTALITY

1979 • 151 citations

Influence of Protein Under- and Overnutrition on Spontaneous Tumor Prevalence in the Rat

1973 • 148 citations

The Dependence of Tumor Formation on the Composition of the Calorie-Restricted Diet as Well as on the Degree of Restriction

1945 • 147 citations

Effect of Dietary Beef Fat on Intestinal Tumor Formation by Azoxymethane in Rats<xref ref-type="fn" rid="fn2">2</xref>

1975 • 146 citations

Alimentary factors in the epidemiology of gastric cancer

1972 • 143 citations

Breast cancer and diet among the Japanese in Hawaii

1978 • 142 citations

Can nutrition explain the pattern of international epidemiology of hormone-dependent cancers?

1975 • 142 citations

Diet as an etiological factor in the development of cancers of the colon and rectum

1975 • 142 citations

CANCER AMONG MEN ON CHOLESTEROL-LOWERING DIETS

1971 • 141 citations

Quantitative nutritional studies with water-soluble, chemically defined diets. VIII. The forced feeding of diets each lacking in one essential amino acid

1959 • 138 citations

Effect of type and amount of dietary fat and 1,2-dimethylhydrazine on biliary bile acids, fecal bile acids, and neutral sterols in rats.

1977 • 134 citations

Studies in the epidemiology of prostatic cancer: expanded sampling.

1977 • 133 citations

Effects of Dietary Fat Level and Dimethylhyd,razine on Fecal Acid and Neutral Sterol Excretion and Colon Carcinogenesis in Rats 2

1974 • 132 citations

Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats.

1979 • 129 citations

Gastrointestinal cancer and nutrition

1969 • 129 citations

Breast cancer incidence according to weight and height in two cities of the Netherlands and in Aichi prefecture, Japan

1977 • 129 citations

Effects of dietary fat and dose level of 7,12-dimethylbenz(alpha)-anthracene on mammary tumor incidence in rats.

1970 • 126 citations

Geographic Patterns of Prostate Cancer in the United States

1978 • 126 citations

Serum cholesterol and risk of death from cancer and other causes in three Chicago epidemiological studies

1981 • 125 citations

Pancreatic carcinoma in azaserine-treated rats: Induction, classification and dietary modulation of incidence

1981 • 122 citations

AN APPARENT INVERSE RELATIONSHIP BETWEEN SERUM CHOLESTEROL AND CANCER MORTALITY IN PUERTO RICO

1981 • 121 citations

Influence of Dietary Fat on the Induction of Mammary Tumors by N -Nitrosomethylurea: Associated Hormone Changes and Differences Between Sprague-Dawley and F344 Rats 2

1977 • 119 citations

Ten-year mortality and morbidity related to serum cholesterol.

1972 • 118 citations

The Contributions of Diet and Childbearing to Breast-cancer Rates

1978 • 118 citations

Factor Analysis of International Cancer Mortality Data and per capita Food Consumption

1974 • 115 citations

Circulating Cholesterol Level and Risk of Death From Cancer in Men Aged 40 to 69 Years

1982 • 113 citations

Aetiological factors in oesophageal cancer in Singapore Chinese

1974 • 111 citations

Foods and diseases.

1977 • 110 citations

Cholesterol and mortality in New Zealand Maoris.

1980 • 103 citations

A retrospective study of renal cancer with special reference to coffee and animal protein consumption

1976 • 98 citations

SERUM CHOLESTEROL AND MORTALITY

1981 • 97 citations

Review: Putative mutagens and carcinogens in foods. I. Nitrate/nitrite ingestion and gastric cancer mortality

1983 • 94 citations

Colorectal cancer and consumption of beef and fat

1975 • 90 citations

Etiology of cancer of the human ovary: a review.

1974 • 89 citations

The role of starches in the etiology of gastric cancer

1974 • 86 citations

Effect of Protein Deprivation of Male Weanling Rats on the Kinetics of Hepatic Microsomal Enzyme Activity

1972 • 84 citations

Effects of reducing the phenylalanine-Tyrosine intake of patients with advanced malignant melanoma

1966 • 78 citations

The effect of dietary protein on carcinogenesis of aflatoxin.

1968 • 76 citations

Serum lipoprotein levels in patients with cancer.

1972 • 75 citations

Further Studies on the Tumor-Promoting Action of Fat

1943 • 74 citations

Enhancement of Experimental Pancreatic Cancer in Syrian Golden Hamsters by Dietary Fat&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;

1981 • 74 citations

Interaction of azaserine and raw soya flour on the rat pancreas.

1981 • 70 citations

Interactions between dietary fats and antioxidants on DMBA-induced mammary carcinomas and on AAF-induced hyperplastic nodules and hepatomas.

1980 • 69 citations

Effects of dietary fat on hepatic mixed-function oxidases and hepatocellular carcinoma induced by aflatoxin B1 in rats.

1979 • 67 citations

Breast cancer mortality and diet in the United States.

1979 • 65 citations

Co-carcinogenic effects of dietary cholesterol in experimental colon cancer

1978 • 60 citations

Obesity and the time of appearance of spontaneous mammary carcinoma in C3H mice.

1953 • 59 citations

COLON CANCER AND BLOOD-CHOLESTEROL

1974 • 59 citations

Effect of Dietary Polyunsaturated Fat on the Growth of a Transplantable Adenocarcinoma in C3HAvyfB Mice

1977 • 59 citations

Diet, transit time, stool weight, and colon cancer in two Scandinavian populations

1978 • 58 citations

Gastric Acid Secretory Value of Different Foods

1960 • 57 citations

Nitrogen Intake and Tumorigenesis in Rats Injected with 1,2-Dimethylhydrazine

1976 • 56 citations

Increased renal carcinogenesis by dimethyl nitrosamine in protein deficient rats.

1970 • 54 citations

Tar Cancer in Mice. II. The Condition of the Skin, when Modified by External Treatment or Diet, as a Factor in Influencing the Cancerous Reaction

1930 • 53 citations

Cereal consumption and gastric cancer

1967 • 52 citations

Colon cancer in a low-risk population

1978 • 49 citations

Effects of diet on colon carcinogenesis and the immune system in rats treated with 1,2-dimethylhydrazine.

1978 • 48 citations

Neoplasms and environmental factors.

1967 • 48 citations

Serum Cholesterol and Human Colon Cancer&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1981 • 46 citations

Dietary Protein, Aryl Hydrocarbon Hydroxylase and Chemical Carcinogenesis in Rats

1979 • 46 citations

The effect of protein deficiency on the binding of aflatoxin B1 to rat liver macromolecules

1976 • 45 citations

Feeding studies on sodium cyclamate, saccharin and sucrose for carcinogenic and tumour-promoting activity

1970 • 44 citations

Low Cholesterol Level as Risk Factor for Noncoronary Death in Middle-aged Men

1981 • 43 citations

The effect of heated fat on the carcinogenic activity of 2-acetylaminofluorene.

1962 • 42 citations

Factors Associated with Adenocarcinomas of the Large Bowel in Puerto Rico

1979 • 38 citations

Tumor response to phenylalanine-tyrosine-limited diets.

1969 • 35 citations

Toxic Response of Rats to Cyclamates in Chow and Semisynthetic Diets

1972 • 34 citations

Social Class Differences Among Patients With Large-Bowel Cancer in Cali, Colombia&lt;xref ref-type="fn" rid="fn2"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;

1975 • 34 citations

Associations between breast-cancer mortality rates, child-bearing and diet in the United Kingdom

1980 • 32 citations

Some host-tumor relationships with respect to nitrogen.

1954 • 32 citations

Effect of varying levels of dietary protein on tumor development and lipid metabolism in rats exposed to aflatoxin

1976 • 32 citations

Tumor Response to Phenylalanine-Tyrosine-Limited Diets1

1969 • 31 citations

Nutrition and Colon Cancer

1979 • 30 citations

Nutrition and experimental carcinogenesis.

1978 • 29 citations

A comparison of the effects of the hypocholesteremic agents, cholestyramine and candicidin, on the induction of intestinal tumors in rats by azoxymethane.

1977 • 28 citations

The effects of vitamin A-deficient diets containing lactose in producing bladder calculi and tumors in rats

1981 • 26 citations

Production of tumors in rats by 2-aminofluorene and 2-acetylaminofluorene; failure of liver extract and of dietary protein level to influence liver tumor production.

1947 • 25 citations

THE HUMEAN FOG: CANCER AND CHOLESTEROL

1981 • 25 citations

Effect of Casein, Lactalbumin, and Ovalbumin on 3-Methylcholanthrene-Induced Mammary Carcinoma in Rats&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1964 • 24 citations

Prolonged Survival of Skin and Tumor Allografts in Mice on High-Fat Diets: Brief Communication 2

1977 • 24 citations

The Influence of Diet on the Walker Rat Carcinoma 256, and Its Response to X-Radiation—Cytological and Histological Investigations

1950 • 24 citations

Effect of Dietary Fat on X-Ray-Induced Mammary Cancer in Sprague-Dawley Rats&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1980 • 23 citations

Effects of dietary carbohydrate on the incidence of mammary tumors induced in rats by 7, 12‐dimethylbenz[α] anthracene

1979 • 23 citations

Effect of Diethylstilbestrol on Mammary Tumor Formation in Strain C3H Mice Fed a Low Cystine Diet

1944 • 22 citations

Cholesterol excretion and colon cancer.

1981 • 22 citations

The effects of dietary corn oil on the metabolism and activation of benzo[a]pyrene by the benzo[a]pyrene metabolizing enzymes of the mouse

1983 • 21 citations

Breast cancer rates in populations of single women

1975 • 21 citations

Influence of Nutrition on Metabolism of Carcinogens

1979 • 21 citations

The influence of dietary casein level on tumor induction with 2-acetylaminofluorene.

1952 • 20 citations

Effect of Diets Deficient in Certain Amino Acids on the Induction of Leukemia in DBA Mice&lt;xref ref-type="fn" rid="fn2"&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/xref&gt;

1947 • 20 citations

Ultrastructural modifications of intestinal and colonic mucosa induced by free or bound bile acids.

1981 • 20 citations

Source of Tumor Proteins. I. Effect of a Low-Nitrogen Diet on the Establishment and Growth of a Transplanted Tumor&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;

1945 • 19 citations

The influence of estrogen on cancer incidence and adrenal changes in ovariectomized mice on calorie restriction.

1949 • 19 citations

Effects of bile acids on induced colon cancer in rats

1978 • 19 citations

The Effect of Dietary Casein on the Induction of Lung Tumours by the Injection of 9,10-Dimethyl-1,2-Benzanthracene (DMBA) into Newborn Mice

1964 • 18 citations

The levels of carcinogenic azo dyes in the livers of rats fed various diets containing p-dimethylaminoazobenzene; relationship to the formation of hepatomas.

1948 • 18 citations

Effect of nutritional status on immune phenomena

1974 • 17 citations

Modification of a transplantable colon tumor and immune responses in mice fed different sources of protein, fat and carbohydrate

1983 • 17 citations

Future inquiries into the epidemiology of gastric cancer.

1975 • 15 citations

The Effect of Dietary Cystine on the Reaction of Dilute Brown Mice to Methylcholanthrene&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt; (Preliminary Report)

1941 • 15 citations

[Epidemiological problems of pancreas cancer].

1968 • 14 citations

Bile Acids: Effects on Absorption of 1,2-Dimethylhydrazine and 7, 12-Dimethylbenz[&lt;italic&gt;a&lt;/italic&gt;]anthracene in the Colon of the Rat and Guinea Pig&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;

1982 • 12 citations

Modification of herpes 2-transformed cell-induced tumors in mice fed different sources of protein, fat and carbohydrate

1982 • 11 citations

Fecal neutral steroids in two Japanese populations with different colon cancer risks.

1983 • 11 citations

Nitrite stability and nitrosation potential in human gastric juice

1981 • 11 citations

Glucose increases experimentally induced colorectal cancer: A preliminary report

1981 • 9 citations

Effect of dietary fats on tumorigenicity of two sarcoma cell lines.

1979 • 8 citations

The onset of mammary adenocarcinoma in mice: A possible correlation with nutrition

1974 • 7 citations

An Attempt of Low Phenylalanine Diet Therapy for Chronic Myelogenous Leukemia (Preliminary Report)

1966 • 6 citations

Advances in modern toxicology. Vol. 5. Mutagenesis.

1978 • 2 citations

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