CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

1992 • 3,099 citations

REVERSIBILITY OF LYMPHOMAS AND LYMPHOPROLIFERATIVE LESIONS DEVELOPING UNDER CYCLOSPORIN-STEROID THERAPY

1984 • 1,284 citations

Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation

1995 • 1,207 citations

Infusions of Donor Leukocytes to Treat Epstein-Barr Virus-Associated Lymphoproliferative Disorders after Allogeneic Bone Marrow Transplantation

1994 • 1,078 citations

Inhibition of antigen processing by the internal repeat region of the Epstein–Barr virus nuclear antigen-1

1995 • 820 citations

High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines

1990 • 709 citations

Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies.

1992 • 519 citations

Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development.

1992 • 402 citations

Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells.

1993 • 368 citations

The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein.

1994 • 352 citations

Epstein-Barr virus latent gene expression in uncultured peripheral blood lymphocytes

1992 • 258 citations

Epstein-Barr virus nuclear protein 2 transactivation of the latent membrane protein 1 promoter is mediated by J kappa and PU.1

1995 • 250 citations

Alterations in DNA methylation may play a variety of roles in carcinogenesis

1995 • 220 citations

A Survey of Epstein-Barr Virus DNA in Lymphoid Tissue: Frequent Detection in Hodgkin’s Disease

1989 • 219 citations

Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless.

1994 • 218 citations

5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael

1989 • 149 citations

Epstein-Barr virus DNA is abundant and monoclonal in the Reed-Sternberg cells of Hodgkin's disease: association with mixed cellularity subtype and Hispanic American ethnicity

1994 • 147 citations

Heterogeneous expression of Epstein-Barr virus latent proteins in endemic Burkitt's lymphoma

1995 • 147 citations

EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1

1994 • 132 citations

Functions for DNA Methylation in Vertebrates

1993 • 120 citations

Epstein-Barr virus and Burkitt's lymphoma.

1992 • 118 citations

Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies

1987 • 115 citations

The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.

1995 • 114 citations

Activation of Epstein-Barr virus replication in Hodgkin and Reed- Sternberg cells

1991 • 97 citations

Epstein-barr virus integration in human lymphomas and lymphoid cell lines

1992 • 93 citations

Rapid in situ hybridization for the diagnosis of latent Epstein-Barr virus infection

1993 • 67 citations

Limiting-dilution analysis of the HLA restriction of anti-Epstein-Barr virus-specific cytolytic T lymphocytes.

1991 • 65 citations

The Insertion of Foreign DNA Into Mammalian Genomes and Its Consequences: A Concept in Oncogenesis

1995 • 48 citations

CpG methylation of viral DNA in EBV‐associated tumours

1990 • 32 citations

Molecular analysis of Hodgkin's disease‐derived cell lines

1988 • 15 citations

Tumorigenic DNA viruses

1989 • 8 citations

Deleted Work

1955 • 0 citations