An exclusion map for pre-eclampsia: assuming autosomal recessive inheritance.

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

1989 • 3,458 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

1987 • 1,920 citations

Primary structure and expression of a functional human glucocorticoid receptor cDNA

1985 • 1,851 citations

Variable Number of Tandem Repeat (VNTR) Markers for Human Gene Mapping

1987 • 1,683 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

A routine method for the establishment of permanent growing lymphoblastoid cell lines

1986 • 628 citations

Characterization of a panel of highly variable minisatellites cloned from human DNA

1987 • 534 citations

Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986

1990 • 524 citations

Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region.

1989 • 479 citations

Linkage of a Gene Causing Familial Amyotrophic Lateral Sclerosis to Chromosome 21 and Evidence of Genetic-Locus Heterogeneity

1991 • 373 citations

A candidate for the cystic fibrosis locus isolated by selection for methylation-free islands

1987 • 339 citations

Mapping of mutation causing Friedreich's ataxia to human chromosome 9

1988 • 307 citations

Genetic and familial predisposition to eclampsia and pre‐eclampsia in a defined population

1990 • 303 citations

Genetics of hypertension in pregnancy: possible single gene control of pre‐eclampsia and eclampsia in the descendants of eclamptic women

1986 • 266 citations

Amplification of a hightly polymorphic VNTR segment by the polymerase chain reaction

1989 • 244 citations

The familial factor in toxemia of pregnancy.

1968 • 231 citations

SOME OBSERVATIONS ON THE INCIDENCE OF PRE‐ECLAMPSIA

1958 • 171 citations

Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.

1986 • 146 citations

THE INCIDENCE OF SEVERE PRE‐ECLAMPSIA AMONGST MOTHERS AND MOTHERS‐IN‐LAW OF PRE‐ECLAMPTICS AND CONTROLS

1981 • 138 citations

HLA ANTIGENS IN SEVERE PRE-ECLAMPSIA

1978 • 115 citations

Altered Platelet Calcium Metabolism as an Early Predictor of Increased Peripheral Vascular Resistance and Preeclampsia in Urban Black Women

1990 • 112 citations

Genetic control of susceptibility to eclampsia and miscarriage

1988 • 111 citations

Isolation and mapping of a polymorphic DNA sequence (pMCT118) on chromosome 1p [D1S80]

1988 • 106 citations

Isolation and mapping of a polymorphic DNA sequence pYNH24 on chromosome 2 (D2S44)

1987 • 100 citations

Genetic control of severe pre-eclampsia.

1979 • 92 citations

Eclampsia still kills

1988 • 88 citations

Linkage disequilibrium and evolutionary relationships of DNA variants (restriction enzyme fragment length polymorphisms) at the serum albumin locus.

1984 • 79 citations

Tetranucleotide repeat polymorphism in the vWF gene

1990 • 76 citations

ASSOCIATION BETWEEN SUSCEPTIBILITY TO PRE-ECLAMPSIA WITHIN FAMILIES AND HLA DR4

1989 • 65 citations

Dinucleotide repeat polymorphism at the D6S89 locus

1990 • 63 citations

Absence of close linkage between maternal genes for susceptibility to pre-eclampsia/eclampsia and HLA DRβ

1990 • 56 citations

The Molecular Basis of HLA—Disease Association

1989 • 55 citations

Exclusion mapping.

1987 • 52 citations

von Willebrand factor multimeric levels and patterns in patients with severe preeclampsia.

1990 • 44 citations

Dinucleotide repeat polymorphisms at the D5S107, D5S108, D5S111, D5S117 and D5S118 loci

1990 • 41 citations

FACTOR VIII COMPLEX IN NORMAL PREGNANCY, PRE‐ECLAMPSIA AND FETAL GROWTH RETARDATION

1981 • 39 citations

Pre‐eclampsia is associated with HLA‐DR4 sharing between mother and fetus

1990 • 39 citations

Cloning of the human genomic amiloride-sensitive Na+H+ antiporter gene, identification of genetic polymorphisms, and localization on the genetic map of chromosome 1p

1990 • 35 citations

An exclusion map of Marfan syndrome.

1990 • 34 citations

Isolation and mapping of a polymorphic DNA sequence (pYNZ32) on chromosome 4p [D4S125]

1988 • 30 citations

Dinucleotide repeat polymorphism at the D4S174 locus

1990 • 29 citations

Linkage mapping of the highly informative DNA marker D21S156 to human chromosome 21 using a polymorphic GT dinucleotide repeat

1990 • 29 citations

Localization of a human Na+, K+-ATPase ? subunit gene to chromosome 19q12�q13.2 and linkage to the myotonic dystrophy locus

1988 • 25 citations

Dinucleotide repeat polymorphism at the D15S87 locus

1990 • 20 citations

Association of HLA DR4 with the risk of recurrence of pregnancy hypertension.

1988 • 20 citations

Xhol polymorphism at the human pronatriodilatin (hPND) gene locus

1986 • 18 citations

Isolation and mapping of a polymorphic DNA sequence pEFD126.3 on chromosome 9q (D9S7)

1987 • 18 citations

Isolation and mapping of a polymorphic DNA sequence (pEFD145) on chromosome 3 [D3S32]

1988 • 18 citations

Isolation and mapping of a polymorphic DNA sequence pEFD33.2 on chromosome 12 [D12S14]

1988 • 14 citations

Human renin (REN) gene locus: BgIII, RsaI and TaqI RFLPs

1986 • 14 citations

Isolation and mapping of a polymorphic DNA sequence MCT128.1 on chromosome 11 [D11S285]

1988 • 13 citations

Isolation and mapping of a polymorphic DNA sequence (pEFZ31) on chromosome 22 [D22S32]

1988 • 12 citations

Isolation and mapping of a polymorphic DNA sequence (pMCT15) on chromosome 21 [D21S113]

1988 • 9 citations

Isolation and mapping of a polymorphic DNA sequence (pEFD64.1) on chromosome 3 [D3S42]

1988 • 6 citations

Isolation and mapping of a polymorphic DNA sequence pJCZ3.1 on chromosome 19 [D19S20]

1988 • 6 citations

Isolation and mapping of a polymorphic DNA sequence (pJCZ30) on chromosome 6 [D6S37]

1988 • 5 citations

Isolation and mapping of a polymorphic DNA sequence (cMHZ47) on chromosome 13 [D13S52]

1988 • 4 citations

Isolation and mapping of a polymorphic DNA sequence (pJCZ67) on chromosome 7 [D7S396]

1988 • 3 citations

MspI andHindIII restriction fragment length polymorphisms at the human Na,K-ATPase β-subunit (ATP1B) gene locus

1988 • 3 citations

Isolation and mapping of a polymorphic DNA sequence (pCMM66) on chromosome 14 (D14S22]

1988 • 2 citations