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Hirschsprung’s Disease: Its Aetiology, Pathogenesis and Differential Diagnosis

Data up to Jan 2025

Published1974
Citations100
References162

Total Citations Per Year

Abstract

References (162)

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

1964 • 3,400 citations

Congenital Malformations

1953 • 1,096 citations

Physiology of the Digestive Tract.

1961 • 587 citations

Resection of Rectum and Rectosigmoid with Preservation of the Sphincter for Benign Spastic Lesions Producing Megacolon. An Experimental Study

2023 • 477 citations

The origin of intrinsic ganglia of trunk viscera from vagal neural crest in the chick embryo

1954 • 431 citations

The Cytochemical Localization of Oxidative Enzymes

1958 • 390 citations

A LAW OF DENERVATION

1939 • 385 citations

The Cytochemical Localization of Oxidative Enzymes

1958 • 377 citations

Histologische Geschwulstdiagnostik

1957 • 330 citations

Adrenergic innervation of the intestinal wall studied by fluorescence microscopy

1964 • 310 citations

Embryogenesis of intramural ganglia of the gut and its relation to Hirschsprung's disease

1967 • 281 citations

MYENTERIC PLEXUS IN CONGENITAL MEGACOLON

1948 • 265 citations

Acetylcholinesterase activity in suction biopsies of the rectum in the diagnosis of Hirschsprung's disease

1972 • 241 citations

The Genetics of Hirschsprung's Disease

1967 • 236 citations

HIRSCHSPRUNG'S DISEASE AND IDIOPATHIC MEGACOLON*1

1949 • 216 citations

Observations on the appearance of norepinephrine in the sympathetic nervous system of the chick embryo

1965 • 199 citations

Hirschsprung's Disease: A New Concept of the Etiology

1949 • 197 citations

The anatomy of Auerbach's plexus

1931 • 172 citations

A family study of Hirschsprung's disease

1963 • 171 citations

Transmitter histochemistry of the sympathetic adrenergic nervous system

1967 • 160 citations

FUNCTIONAL INTESTINAL OBSTRUCTION ON A CONGENITAL NEUROGENIC BASIS IN INFANCY

1948 • 156 citations

Gastrointestinal ganglioneuromas; brief review with report of a duodenal ganglioneuroma.

1957 • 144 citations

HIRSCHSPRUNG'S DISEASE

1951 • 140 citations

Defecation and continence

1970 • 137 citations

Nonsurgical Test for the Diagnosis of Hirschsprung's Disease

1968 • 134 citations

VIII. A contribution to our knowledge of the enteric plexuses

1927 • 132 citations

Autonomic nerves in rectum and colon in Hirschsprung's disease. A cholinesterase and catecholamine histochemical study.

1969 • 128 citations

Adrenergic innervation of the alimentary canal

1971 • 121 citations

A rectal suction biopsy tube for use in the diagnosis of Hirschsprung's disease

1969 • 116 citations

THE PATHOLOGIC PHYSIOLOGY OF CONGENITAL MEGACOLON

1951 • 116 citations

A clinical evaluation of ano-rectal pressure studies in the diagnosis of Hirschsprung's disease

1972 • 114 citations

Studies on Some Systems of Adrenergic Synaptic Terminals in the Abdominal Ganglia of the Cat

1965 • 113 citations

Diagnosis of Hirschsprung's Disease Excluded by Rectal Suction Biopsy

1965 • 109 citations

Congenital Megacolon. A Comparison of the Spastic and Hypertrophied Segments with Respect to Cholinesterase Activities and Sensitivities to Acetylcholine, DFP and the Barium Ion

1953 • 105 citations

Colonic motor activity and bowel function. I. Normal movement of contents.

1968 • 103 citations

LOCALIZED ABSENCE OF THE GANGLION CELLS OF THE MYENTERIC PLEXUS IN CONGENITAL MEGACOLON

1940 • 92 citations

Experience with rectal suction biopsy in the diagnosis of Hirschsprung's disease

1969 • 89 citations

Rectal Biopsy as an Aid in the Diagnosis of Hirschsprung's Disease

1955 • 89 citations

Physiological implications of the histochemical localization of monoamine oxidase

1954 • 84 citations

Megacolon, a Complication of Ulcerative Colitis

1950 • 79 citations

Congenital Megacolon (Hirschsprung's Disease)

1954 • 74 citations

Some new observations on megacolon in infancy and childhood with special reference to the management of megasigmoid and megarectum

1964 • 74 citations

Imperforate anus: Anorectosigmoid pressure studies as a quantitative evaluation of postoperative continence

1969 • 71 citations

Studies of Distal Colonic Motility in Children

1955 • 63 citations

Das Megacolon

1968 • 63 citations

Fulminating Ulcerative Colitis With Marked Colonic Dilation: A Clinicopathologic Study

1962 • 62 citations

Adrenergic Innervation of Bowel in Hirschsprung's Disease

1969 • 62 citations

Adrenergic myenteric nerves in Hirschsprung's disease.

1968 • 61 citations

[On the distribution of catecholamines in the human intestines].

1967 • 60 citations

Selective destruction of the myenteric plexus: Its relation to Hirschsprung's disease, achalasia of the esophagus and hypertrophic pyloric stenosis

1967 • 57 citations

�ber die Verteilung von Catecholaminen im Darm des Menschen

1967 • 56 citations

The Pathophysiology of Aganglionosis of the Entire Colon (Zuelzer-Wilson Syndrome) Morphometric Investigations of the Extent of Sacral Parasympathetic Innervation of the Circular Muscles of the Aganglionic Colon

1972 • 55 citations

Discussion on Megacolon and Megarectum with the Emphasis on Conditions other than Hirschsprung's Disease

1961 • 54 citations

Seminar on pseudo-Hirschsprung's disease and related disorders.

1966 • 52 citations

Some newer aspects on Hirschsprung's disease and allied disorders

1966 • 51 citations

Megacolon in the Newborn.

1945 • 50 citations

Aganglionosis of the small intestine.

1966 • 49 citations

Megacolon: Evidence in favour of a neurogenic origin

1932 • 48 citations

Myenteric plexus in Hirschsprung's disease.

1967 • 47 citations

Incubation media for routine laboratory work on enzyme histotopochemistry.

1971 • 46 citations

The origin of the vagi and the parasympathetic ganglion cells of the viscera of the chick

1942 • 45 citations

THE ROLE OF THE INTRINSIC MUCOSAL REFLEX IN THE FLUID TRANSPORT THROUGH THE DENERVATED COLONIC LOOP

1961 • 45 citations

Aganglionic Megacolon, Pheochromocytoma, Megaloureter, and Neurofibroma

1957 • 43 citations

Pathology of the ganglionic-aganglionic junction in congenital megacolon.

1960 • 43 citations

The development of the sympathetic nervous system in man

1920 • 42 citations

THE ROLE OF THE GANGLION CELLS IN THE SMALL INTESTINE TAKEN IN THE INTESTINAL INTRINSIC REFLEX

1961 • 42 citations

Electron microscopy of myenteric nerves in Hirschsprung's disease and in normal bowel

1970 • 42 citations

PLEXIFORM NEUROFIBROMATOSIS OF THE COLON SIMULATING HIRSCHSPRUNG'S DISEASE.

1964 • 42 citations

THE DIAGNOSIS OF COLONIC AND TERMINAL ILEAL AGANGLIONOSIS.

1964 • 41 citations

NORMAL AND ABNORMAL INTERORBITAL DISTANCES, WITH SPECIAL REFERENCE TO MONGOLISM

1965 • 41 citations

Seminar on pseudo-Hirschsprung's disease and related disorders

1966 • 40 citations

Zonal Colonic Aganglionosis, a Variant of Hirschsprung's Disease

1972 • 40 citations

Untersuchungen über den geweblichen Aufbau der Geschwülste des peripheren Nervensystems

1934 • 39 citations

HISTOCHEMICAL DIAGNOSIS OF HIRSCHSPRUNG'S DISEASE

1969 • 38 citations

Congenital megacolon of a man 54 years of age: report of case.

1950 • 38 citations

Functional and morphological response of the dog colon to ischaemia

1972 • 38 citations

AGANGLIONIC AND FUNCTIONAL MEGACOLON IN CHILDREN—A DIAGNOSTIC DILEMMA

1965 • 37 citations

Acquired Megacolon As a Complication of Recto-sigmoidectomy for Hirschsprung's Disease

1965 • 37 citations

Sympathetic innervation of the colon in Hirschsprung's disease: A histochemical study

1968 • 35 citations

The Relation of Megacolon and Megaloureter

1955 • 35 citations

Megacolon and megarectum in Chagas' disease.

1961 • 35 citations

Congenital abnormalities of intestinal innervation; absence of innervation of jejunum, ileum and colon in siblings.

1958 • 32 citations

Chagas disease of the colon and rectum

1969 • 31 citations

Modern trends in surgery

1962 • 30 citations

Total Aganglionic Colon in an Adult

1966 • 29 citations

Cholinesterases and monoamine oxidase in congenital megacolon

1961 • 29 citations

Hirschsprung's disease and mongolism.

1966 • 29 citations

Megacolon, with particular reference to Hirschsprung's disease.

1955 • 28 citations

A study of the vesical ganglia in children and the relationship to the megaureter megacystis syndrome and Hirschsprung's disease

1963 • 28 citations

Hirschsprung's Disease (Aganglionic Megacolon)

1959 • 27 citations

Diagnosis and Treatment of Aganglionosis of the Myenteric Plexus

1957 • 26 citations

Aganglionosis Involving the Entire Colon and a Variable Length of Small Bowel

1968 • 26 citations

Familial absence of myenteric plexus (congenital megacolon)

1965 • 26 citations

Aganglionosis of the Entire Colon in an Adolescent

1965 • 26 citations

HISTOCHEMICAL DIAGNOSIS OF HIRSCHSPRUNG'S DISEASE

1969 • 26 citations

Congenital Defects in the Pelvic Parasympathetic System

1955 • 25 citations

Pseudo-Hirschsprung's Disease

1965 • 25 citations

Megacolon and megarectum in older children and young adults. Classification and terminology.

1967 • 23 citations

THE MECONIUM-PLUG SYNDROME AND HIRSCHSPRUNG'S DISEASE.

1965 • 23 citations

Constipation in infants and children.

1971 • 23 citations

Adrenergic innervation of the intestinal smooth musculature

1969 • 22 citations

A genetical study of Hirschsprung's disease; congenital intestinal aganglionosis.

1966 • 22 citations

Plexiform neurofibromatosis of the colon as a cause of congenital megacolon

1965 • 22 citations

Hirschsprung's disease in the neonatal period

1957 • 22 citations

Megarectum and Megacolon in Adolescents and Young Adults: Results of Treatment at St. Mark's Hospital

1967 • 21 citations

Management of Symptomatic Aganglionic Megacolon in Early Infancy

1957 • 20 citations

Recent advances in pediatric surgery

1969 • 20 citations

Kontinenz, Superkontinenz und Inkontinenz im Anorektalbereich*

1965 • 19 citations

The use of telemetering capsules in disorders of the alimentary tract: Part I A technique for recording pressure changes

1962 • 18 citations

AGANGLIONOSIS OF THE COLON AND TERMINAL ILEUM

1965 • 18 citations

Aganglionosis of the intestine in siblings.

1963 • 18 citations

[Light and electron microscopic findings on the autonomic nervous system of the colon in human ulcerative colitis].

1965 • 18 citations

Licht- und elektronenmikroskopische Befunde am vegetativen Nervensystem des Colon bei Colitis ulcerosa des Menschen

1965 • 18 citations

THE ROLE OF THE INTRINSIC MUCOSAL REFLEX IN THE FLUID TRANSPORT THROUGH THE DENERVATED INTESTINAL LOOP

1959 • 16 citations

Neonatal Abdominal Emergencies

1971 • 16 citations

Hirschsprung's Disease

1971 • 16 citations

NEUROFIBROMATOSIS OF THE COLON, SMALL INTESTINE AND MESENTERY IN A CHILD

1942 • 16 citations

Adrenergic myenteric nerves in Hirschsprung's disease

1968 • 16 citations

Megarectum in the older child.

1967 • 15 citations

Hirschsprung's Disease in the Neonatal Period

1955 • 15 citations

Total intestinal aganglionosis presenting as duodenal obstruction.

1971 • 15 citations

Chronic constipation in children, with particular reference to Hirschsprung's disease.

1952 • 14 citations

AUTONOMIC AND PHARMACOLOGIC CONTROL OF COLONIC ACTIVITY

1954 • 14 citations

Fortschritte in der Diagnostik des Aganglionären Segments

1972 • 14 citations

Neurofibroma of the rectum in a patient with von Recklinghausen's disease

1958 • 14 citations

Cutaneous and intestinal neurofibromatosis

1960 • 13 citations

Some Aspects of Adult Megacolon

1971 • 13 citations

Visceral Innervation and Its Relation to Personality.

1952 • 13 citations

[New viewpoints on the pathogenesis and clinical picture of Hirschsprung's disease].

1968 • 13 citations

Intestinal Obstruction in the Newborn

1957 • 10 citations

Megarectum in the Older Child

1967 • 10 citations

Hirschsprungsche Krankheit mit langem engen Segment

1969 • 10 citations

Histochemistry and electron microscopy of rectum and colon in Hirschsprung's disease.

1970 • 9 citations

Bowel innervation in Hirschsprung's disease.

1969 • 8 citations

Histochemistry and election microscopy of rectum and colon in Hirschsprung's disease

1971 • 8 citations

Zur Physiologie der Peristaltik des Dünndarms

1965 • 8 citations

Classification and Terminology

1967 • 7 citations

Hirschsprung's Disease: Congenital Intestinal Aganglionosis

1965 • 7 citations

Histochemistry and Electron Microscopy of Rectum and Colon in Hirschsprung's Disease

1970 • 7 citations

Problems of methodology and interpretation, and analysis of records

1968 • 7 citations

Röntgendiagnostik der Hirschsprungschen Krankheit im Neugeborenenalter und bei atypischen Fällen

1972 • 6 citations

Problems in the Diagnosis of Hirschsprung’s Disease

1972 • 6 citations

The Myenteric Plexus in Hrischsprung's Disease

1967 • 6 citations

Progress in Proctology

1969 • 6 citations

Histochemische Darstellung der spezifischen Cholinesterase (Azetylcholinesterase) in den nerv�sen Formationen bei einem Fall von neurogener Appendicopathie mit zentraler Neurombildung

1961 • 6 citations

Visceral Innervation and Its Relation to Personality

1952 • 5 citations

Pelvic Colectomy for Obstinate Constipation

1967 • 5 citations

Recent Advances in Pediatric Surgery

1975 • 5 citations

THE MECHANICS OF THE DIGESTIVE TRACT.

1922 • 5 citations

[Enzyme histochemical diagnosis of Hirschsprung's disease].

1971 • 5 citations

Use of circumferential tangential cryostat sections of the intestine in the diagnosis of Hirschsprung's disease

1967 • 5 citations

Funktionelle Untersuchungen beim Morbus Hirschsprung

1972 • 3 citations

Rektoskopische Probeexzision in der Diagnostik des Megacolon congenitum

1962 • 3 citations

Development of neural control of alimentary motor function in the vertebrates

1968 • 2 citations

Zur Bedeutung der rectalen Saugbiopsie beim aganglionären Segment

1972 • 2 citations

74. Probleine bei der Diagnostik des Megacolon congenitum und ihre konsequenzen f�r die operative therapie

1970 • 2 citations

The Pathology of Megacolon

1969 • 2 citations

Hirschsprungsche Erkrankung Neurohistologische Untersuchungen

1972 • 2 citations

CONGENITAL INTESTINAL AGANGLIONOSIS

1967 • 2 citations

Surgery of Megacolon

1969 • 2 citations

[Rectal localization of Recklinghausen's disease].

1959 • 1 citations

Some Differences Between Geometrical and Dynamical Figures of the Moon

1972 • 1 citations

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