Chemical and Environmental Agents in Gastrointestinal Carcinogenesis

Promoting Effect of Bile Acids on Colon Carcinogenesis After Intrarectal Instillation of N -Methyl- N ′ nitro- N -nitrosoguanidine in Rats 2

1974 • 717 citations

Acute and chronic effects of aflatoxin on the liver of domestic and laboratory animals: a review.

1969 • 510 citations

Metabolic epidemiology of colon cancer:Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps

1977 • 404 citations

A study of etiological factors in cancer of the esophagus

1961 • 390 citations

Tumour Production in Glandular Stomach of Rat by N-Methyl-N′-Nitro-N-Nitrosoguanidine

1967 • 343 citations

Some Toxic Properties of Dimethylnitrosamine

1954 • 317 citations

Nitrite and Nitrate Are Formed by Endogenous Synthesis in the Human Intestine

1978 • 292 citations

Selektive Erzeugung von Darmkrebs bei Ratten durch 1,2-Dimethyl-hydrazin

1967 • 273 citations

Promoting Effect of Sodium Deoxycholate on Colon Adenocarcinomas in Germfree Rats2

1976 • 264 citations

Colon carcinogens: Their metabolism and mode of action

1971 • 234 citations

Carcinoma of the Colon and Antecedent Epithelium.

1971 • 213 citations

Effects in Rats of Sodium Chloride on Experimental Gastric Cancers Induced by N-Methyl-N′-nitro-N-nitrosoguanidine or 4-Nitroquinoline-1-oxide2

1975 • 213 citations

The role of colon anaerobes in the metabolism of bile acids and steroids, and its relation to colon cancer

2006 • 199 citations

The effect of bile on the induction of experimental intestinal tumors in rats

1974 • 180 citations

A rat model for studying colonic cancer: Effect of cholestyramine on induced tumors

1973 • 161 citations

Zinc Deficiency and Methylbenzylnitrosamine-lnduced Esophageal Cancer in Rats1

1978 • 155 citations

Isolation and identification of a hepatotoxic factor in herring meal produced from sodium nitrite preserved herring

1964 • 149 citations

Rat Colon Carcinomas Associated with Aflatoxin and Marginal Vitamin A 2 3

1973 • 145 citations

Pathophysiology of Carcinogenesis in Digestive Organs

1978 • 126 citations

Contamination of beer with trace quantities of N-nitrosodimethylamine

1979 • 125 citations

The induction of intestinal neoplasms in rats with the glycoside cycasin and its aglycone

1965 • 115 citations

Acute and Chronic Effect of Dietary Cholic Acid on Colonic Epithelial Cell Proliferation

1981 • 109 citations

Large-Bowel Cancer: An Epidemiologic Jigsaw Puzzle

1975 • 104 citations

Polychlorinated Biphenyl- and Triphenyl-Induced Gastric Mucosal Hyperplasia in Primates

1973 • 103 citations

Cell Renewal in Familial Polyposis: Comparison Between Polyps and Adjacent Healthy Mucosa

1972 • 100 citations

Experimental ulcerative disease of the colon in animals.

1973 • 99 citations

Cardiovascular lesions and various tumors found in rats given T-2 toxin, a trichothecene metabolite of Fusarium.

1979 • 93 citations

Cell Renewal in the Human Rectum

1970 • 86 citations

Metabolism of aflatoxin B1 and identification of the major aflatoxin B1-DNA adducts formed in cultured human bronchus and colon.

1979 • 75 citations

Carcinoma of the Glandular Stomach in Rats given Diets containing Aflatoxin

1966 • 73 citations

REDUCTION OF GASTRTC CARCINOGENS WITH ASCORBIC ACID^*

1975 • 71 citations

Endemic and Morphologic Similarities Existing between Spontaneous Colonic Neoplasms in Man and 3

1965 • 66 citations

The mechanism of carcinogenic action of 1,2‐dimethylhydrazine (sdmh) in rats

1975 • 61 citations

Organ-specific effects of the carcinogen methylazoxymethanol related to metabolism by nicotinamide adenine dinucleotide-dependent dehydrogenases.

1977 • 60 citations

Cocarcinogens of the diterpene ester type fromCroton flavens L. and esophageal cancer in Curaçao

1978 • 60 citations

Effects of Alcohol on Gastric Mucosa

1956 • 50 citations

Host Resistance to Gastric Adenocarcinomatosis in Three Strains of Rats Ingesting N-Methyl-N′-Nitro-N-Nitrosoguanidine

1973 • 48 citations

Dimethylnitrosamine in Chinese marine salt fish

1973 • 47 citations

Beneficial effect of cholestyramine in sclerosing cholangitis

1980 • 46 citations

The epidemiology of cancer of the oesophagus

1978 • 44 citations

The reaction of nitrite with pesticides. II. Formation, chemical properties and carcinogenic activity of the N-nitroso derivative of N-methyl-1-naphthyl carbamate (carbaryl)

1975 • 41 citations

Inhibition of Macromolecular Binding of Benzo[a]pyrene and Inhibition of Neoplasia by Disulfiram in the Mouse Forestomach2

1976 • 40 citations

Inhibition of [3H]thymidine incorporation into DNA of rat esophageal epithelium and related tissues by carcinogenic N-nitroso compounds.

1978 • 36 citations

The large bowel carcinogenic effects of hydrazines and related compounds occurring in nature and in the environment

1977 • 34 citations

Rapid formation of carcinogenic N-nitrosamines by interaction of nitrite with fungicides derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the rat stomach

1974 • 34 citations

Nitrosamines and nitrosamides in the etiology of gastrointestinal cancer

1977 • 33 citations

Polycyclic hydrocarbons in commercially-and home-smoked food in Iceland

1969 • 31 citations

Susceptibility of I nbred Rats to Gastric and Duodenal Carcinomas Induced by N -Methyl- N ′-nitro- N -nitrosoguanidine 2

1974 • 28 citations

Nitrate, nitrite, dimethylnitrosamine and n-nitrosopyrrolidine in some Chinese food products

1977 • 27 citations

BRACKEN FERN AND PAPILLOMA VIRUS IN BOVINE ALIMENTARY CANCER

1980 • 26 citations

Effects of ethanol on the cell proliferation kinetics in the fundic mucosa of dogs

1971 • 23 citations

Relationships of Fusarium Mycotoxins to disorders and tumors associated with alcoholic drinks

1980 • 17 citations

Carcinogens in Scotch

1979 • 15 citations

Studies on the esophagus. II. Enhancement of [3H]thymidine incorporation in the rat esophagus by Bidens pilosa (a plant eaten in south africa) and by croton oil

1979 • 14 citations

Nitrite studies in oesophageal cancer.

1978 • 14 citations

Induction of tumors in the stomach and duodenum of hamsters by N-ethyl-N?-nitro-N-nitrosoguanidine

1974 • 12 citations

Ins and Outs of Nitrites

1980 • 9 citations

[Carcinogenic properties of derivatives of symmetric triazine].

1970 • 5 citations

A brief overview of the toxicological and epidemiological background to the detection and prevention of cancer in agricultural workers.

1976 • 4 citations