Clonal Analysis of Human Recurrent Superficial Bladder Cancer by Immunohistochemistry of P53 and Retinoblastoma Proteins

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53 function and dysfunction

1992 • 1,918 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

1988 • 1,140 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Selection and interpretation of diagnostic tests and procedures. Principles and applications.

1981 • 783 citations

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1991 • 708 citations

The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

1987 • 649 citations

Two molecular pathways to transitional cell carcinoma of the bladder.

1994 • 599 citations

Nuclear Overexpression of p53 Protein in Transitional Cell Bladder Carcinoma: A Marker for Disease Progression

1993 • 544 citations

Clonal Origin of Bladder Cancer

1992 • 538 citations

Altered Expression of the Retinoblastoma Gene Product: Prognostic Indicator in Bladder Cancer

1992 • 348 citations

The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.

1991 • 343 citations

Over‐expression of p53 nuclear oncoprotein in transitional‐cell bladder cancer and its prognostic value

1993 • 264 citations

Altered Expression of Retinoblastoma Protein and Known Prognostic Variables in Locally Advanced Bladder Cancer

1992 • 254 citations

p53 mutations in human bladder cancer: Genotypicversus phenotypic patterns

1994 • 250 citations

Metachronous multifocal development of urothelial cancers by intraluminal seeding

1993 • 223 citations

Association of P53 Nuclear Overexpression and Tumor Progression in Carcinoma in situ of the Bladder

1994 • 221 citations

Superficial Bladder Tumors (Stage pTa, Grades 1 and 2): The Importance of Recurrence Pattern Following Initial Resection

1986 • 210 citations

High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx.

1992 • 204 citations

Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder

1991 • 181 citations

Role of chromosome 9 in human bladder cancer.

1993 • 166 citations

[International histologic classification of tumors].

1983 • 147 citations

Antibiotic And Steroid Therapy of Massive Systemic Bacillus Calmette-Guerin Toxicity

1992 • 67 citations

Optimal BCG Treatment of Superficial Bladder Cancer as Defined by American Trials

1992 • 43 citations

Molecular Genetic Alterations of Chromosome 17 and p53 Nuclear Overexpression in Human Bladder Cancer

1993 • 43 citations

A critical test of the role of population density in producing transformation.

1994 • 20 citations