1918 Influenza: the Mother of All Pandemics

Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic

2002 • 1,760 citations

Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

1988 • 1,151 citations

Characterization of the 1918 influenza virus polymerase genes

2005 • 1,063 citations

Re-emergence of fatal human influenza A subtype H5N1 disease

2004 • 816 citations

Pandemic versus Epidemic Influenza Mortality: A Pattern of Changing Age Distribution

1998 • 708 citations

Initial Genetic Characterization of the 1918 “Spanish” Influenza Virus

1997 • 706 citations

Origin and evolution of the 1918 “Spanish” influenza virus hemagglutinin gene

1999 • 600 citations

The geography and mortality of the 1918 influenza pandemic.

1991 • 512 citations

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus

2004 • 457 citations

Avian Influenza A Viruses Differ from Human Viruses by Recognition of Sialyloligosaccharides and Gangliosides and by a Higher Conservation of the HA Receptor-Binding Site

1997 • 400 citations

A Single Amino Acid Substitution in 1918 Influenza Virus Hemagglutinin Changes Receptor Binding Specificity

2005 • 387 citations

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes

2001 • 278 citations

Specification of Receptor-Binding Phenotypes of Influenza Virus Isolates from Different Hosts Using Synthetic Sialylglycopolymers: Non-Egg-Adapted Human H1 and H3 Influenza A and Influenza B Viruses Share a Common High Binding Affinity for 6′-Sialyl(N-acetyllactosamine)

1997 • 255 citations

Characterization of the 1918 “Spanish” influenza virus neuraminidase gene

2000 • 233 citations

Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts

1992 • 227 citations

Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus

2004 • 200 citations

Global Host Immune Response: Pathogenesis and Transcriptional Profiling of Type A Influenza Viruses Expressing the Hemagglutinin and Neuraminidase Genes from the 1918 Pandemic Virus

2004 • 164 citations

The 1918 Influenza Virus: A Killer Comes into View

2000 • 164 citations

THE INCIDENCE OF NEUTRALIZING ANTIBODIES FOR SWINE INFLUENZA VIRUS IN THE SERA OF HUMAN BEINGS OF DIFFERENT AGES

1936 • 159 citations

1918 Influenza Pandemic Caused by Highly Conserved Viruses with Two Receptor-Binding Variants

2003 • 138 citations

World War I may have allowed the emergence of “Spanish” influenza

2002 • 134 citations

Antigenic similarity of influenza A(H1N1) viruses from epidemics in 1977–1978 to “Scandinavian” strains isolated in epidemics of 1950–1951

1978 • 122 citations

Novel Origin of the 1918 Pandemic Influenza Virus Nucleoprotein Gene

2004 • 121 citations

Statistics of Influenza Morbidity: With Special Reference to Certain Factors in Case Incidence and Case Fatality

1920 • 121 citations

Characterization of the 1918 “Spanish” Influenza Virus Matrix Gene Segment

2002 • 114 citations

Age and Sex Incidence of Influenza and Pneumonia Morbidity and Mortality in the Epidemic of 1928-29 with Comparative Data for the Epidemic of 1918-19: Based on Surveys of Families in Certain Localities in the United States following the Epidemics

1931 • 78 citations

1917 Avian Influenza Virus Sequences Suggest that the 1918 Pandemic Virus Did Not Acquire Its Hemagglutinin Directly from Birds

2002 • 57 citations

The Epidemiology of Influenza

1919 • 54 citations

The 1918 flu and other influenza pandemics: "over there" and back again.

1999 • 51 citations

Relationship of Pre-1918 Avian Influenza HA and NP Sequences to Subsequent Avian Influenza Strains

2003 • 30 citations

THE RECENT EPIDEMIC OF GRIP

1916 • 7 citations