Pathogenesis of Brain Dysfunction in Deficiency of Thiamine, Riboflavin, Pantothenic Acid, or Vitamin B6

The neurosciences. Third study program

1975 • 1,465 citations

Biochemistry and the central nervous system

1986 • 794 citations

The neurosciences-third study program

1975 • 415 citations

Chemical Structure in Relation to Biological Activities of Vitamin B6

1958 • 289 citations

CONVULSIVE SEIZURES IN INFANTS WITH PYRIDOXINE-DEFICIENT DIET

1954 • 260 citations

Taurine—a Possible Neurotransmitter ?

1971 • 256 citations

UREA TREATMENT OF SKIN MALIGNANCIES

1974 • 247 citations

BIOCHEMICAL AND PHYSIOLOGICAL DIFFERENTIATION DURING MORPHOGENESIS—XXI

1957 • 211 citations

THE BIOCHEMICAL LESION IN VITAMIN B1 DEFICIENCY

1936 • 200 citations

THE ENZYMATIC SYNTHESIS OF FATTY ACIDS BY ALDOL CONDENSATION

1958 • 188 citations

l-CYSTATHIONINE IN HUMAN BRAIN

1958 • 179 citations

PYRIDOXINE DEFICIENCY in the HUMAN INFANT

1953 • 171 citations

Encephalopathy of thiamine deficiency: studies of intracerebral mechanisms

1968 • 171 citations

UPTAKE AND RELEASE OF TAURINE FROM RAT BRAIN SLICES

1972 • 168 citations

Arteriosclerotic Lesions in Pyridoxine Deficient Monkeys

2009 • 165 citations

The effect of vitamin B6 deficiency induced by desoxypyridoxine in human beings.

1953 • 163 citations

INTAKE OF VITAMIN B6 AND INFANTILE CONVULSIONS: A FIRST APPROXIMATION OF REQUIREMENTS OF PYRIDOXINE IN INFANTS

1957 • 156 citations

“Pantothenic Acid,” A Growth Determinant of Universal Biological Occurrence

1933 • 147 citations

Effects of Thiamine Deficiency on the Central Nervous System

1961 • 146 citations

THE AMINO ACID REQUIREMENTS OF MAN

1955 • 144 citations

CONVULSIONS IN YOUNG INFANTS AS A RESULT OF PYRIDOXINE (VITAMIN B6) DEFICIENCY

1954 • 142 citations

Production of arteriosclerosis by homocysteinemia.

1970 • 138 citations

Nutritional Disorders of the Nervous System.

1948 • 135 citations

Vitamin B2 and the Pellagra-like Dermatitis in Rats

1934 • 135 citations

A STUDY OF THE NUTRITIONAL DEFECT IN WERNICKE'S SYNDROME

1952 • 128 citations

OBSERVATIONS ON INDUCED THIAMINE (VITAMIN B1) DEFICIENCY IN MAN

1940 • 125 citations

Formation of taurine and isethionic acid in rat brain

1967 • 125 citations

Studies on the Physiological Functions of Thiamine

1961 • 123 citations

EFFECTS OF RIBOFLAVIN DEFICIENCY AND REALIMENTATION ON FLAVIN ENZYMES OF TISSUES

1956 • 122 citations

CNS at the Cellular Level: Identity of Transmitter Agents

1970 • 113 citations

Taurine Pool Sizes in the Rat: Effects of Vitamin B-6 Deficiency and High Taurine Diet

1973 • 111 citations

VITAMIN B6 AND TRANSAMINATION

1945 • 107 citations

�ber die Co-Carboxylase

1937 • 107 citations

Vitamins and Coenzymes

1975 • 107 citations

A COMMON FACTOR IN THE ENZYMATIC ACETYLATION OF SULFANILAMIDE AND OF CHOLINE

1946 • 107 citations

THE EFFECT OF A DEFICIENCY OF VITAMIN B¹ UPON THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS OF THE RAT

1934 • 104 citations

Glial cell changes in the brain stem of thiamine-deficient rats.

1967 • 102 citations

THE EFFECTS OF A THIAMINE ANTAGONIST, PYRITHIAMINE, ON LEVELS OF SELECTED METABOLIC INTERMEDIATES and ON ACTIVITIES OF THIAMINE‐DEPENDENT ENZYMES IN BRAIN and LIVER¹

1968 • 101 citations

Congenital Malformations Induced in Rats by Maternal Nutritional Deficiency

1944 • 100 citations

Ion movements and thiamine

1970 • 99 citations

Nutrition and nerve cell growth.

1970 • 98 citations

Ultrastructural features of early brain stem lesions of thiamine-deficient rats.

1968 • 96 citations

STUDIES ON THE COENZYME ACTIVATION OF GLUTAMIC-ASPARTIC APOTRANSAMINASE

1954 • 96 citations

Pyridoxal phosphate as the coenzyme of the mammalian decarboxylase for <scp>l</scp>-cysteine sulphinic and <scp>l</scp>-cysteic acids

1955 • 95 citations

THE VITAMIN B6 DEFICIENCY SYNDROME IN HUMAN INFANCY: BIOCHEMICAL AND CLINICAL OBSERVATIONS

1963 • 94 citations

PYRIDOXINE DEFICIENCY IN HUMAN BEINGS INDUCED WITH DESOXYPYRIDOXINE 1

1950 • 94 citations

Wernicke's disease: Identity of lesions produced experimentally by B(1) avitaminosis in pigeons with hemorrhagic polioencephalitis occurring in chronic alcoholism in man.

1940 • 93 citations

INDUCED THIAMINE (VITAMIN B1) DEFICIENCY IN MAN

1943 • 93 citations

THE REGIONAL DISTRIBUTION OF TRANSKETOLASE IN THE NORMAL AND THE THIAMINE DEFICIENT NERVOUS SYSTEM

1965 • 92 citations

Hormonal regulation of brain development II. Effect of neonatal thyroidectomy on succinate dehydrogenase and other enzymes in developing cerebral cortex and cerebellum of the rat

1967 • 92 citations

Wernicke's encephalopathy (polioencephalitis hæmorrhagica superior): Its alcoholic and non‐alcoholic incidence

1939 • 92 citations

γ-Aminobutyric Acid (γABA), Vitamin B6, and Neuronal Function—A Speculative Synthesis

1964 • 91 citations

Pyruvic acid as an intermediary metabolite in the brain tissue of avitaminous and normal pigeons

1934 • 90 citations

Blood pyruvate in vitamin B1 deficiency

1935 • 90 citations

THE WERNICKE SYNDROME

1941 • 86 citations

Vitamin B6Deficiency in the Rhesus Monkey

1956 • 86 citations

AVIAN THIAMIN DEFICIENCY

1940 • 85 citations

PANTOTHENIC ACID DEFICIENCY INDUCED IN HUMAN SUBJECTS 1

1955 • 84 citations

Riboflavin Metabolism

1970 • 84 citations

Pantothenic Acid Deficiency in Man1

1958 • 84 citations

PYRIDOXINE DEFICIENCY IN THE NEONATAL RAT

1969 • 83 citations

Lehrbuch der Gehirnkrankheiten für Aerzte und Studirende

2009 • 82 citations

Correlation of Urinary Excretion of Riboflavin with Dietary Intake and Symptoms of Ariboflavinosis

1950 • 82 citations

POLYAMINE SYNTHESIS AND TURNOVER IN RAPIDLY GROWING TISSUES

1970 • 80 citations

Effects of deficiency of vitamin B6 on transsulfuration

1969 • 79 citations

Multiple Congenital Abnormalities in the Rat Resulting from Riboflavin Deficiency Induced by the Antimetabolite Galactoflavin

1956 • 79 citations

THE EFFECT OF PANTOTHENIC ACID DEFICIENCY UPON THE COENZYME A CONTENT AND PYRUVATE UTILIZATION OF RAT AND DUCK TISSUES

1948 • 78 citations

LEVELS AND INTRACELLULAR LOCALIZATION OF GLUTAMATE DECARBOXYLASE AND γ‐AMINOBUTYRATE TRANSAMINASE AND OTHER ENZYMES DURING THE DEVELOPMENT OF THE BRAIN*

1965 • 78 citations

SYNTHESIS AND ACCUMULATION OF POLY AMINES IN REGENERATING RAT LIVER*

1970 • 77 citations

Brain glutamate decarboxylase: changes in the developing rat brain¹

1970 • 76 citations

PYRIDOXINE DEFICIENCY AND DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEM IN THE RAT

1971 • 75 citations

Teratogenicity of Vitamin B ₆ Deficiency: Omphalocele, Skeletal and Neural Defects, and Splenic Hypoplasia

1970 • 73 citations

Homocystinuria due to cystathionine synthase deficiency: Enzymatic and ultrastructural studies

1974 • 73 citations

The uptake, metabolism and release of14C-taurine by rat retina in vitro

1972 • 73 citations

Wernicke's Disease; A Clinical and Pathological Study of 42 Cases

1944 • 72 citations

DETERMINATION AND PROPERTIES OF AN UNIDENTIFIED GROWTH FACTOR REQUIRED BY LACTOBACILLUS BULGARICUS

1949 • 72 citations

Enzyme‐inhibiting factor in subacute necrotizing encephalomyelopathy

1969 • 72 citations

NATURE AND PARTIAL SYNTHESIS OF THE CHICK ANTIDERMATITIS FACTOR

1939 • 71 citations

Inhibitory Action of Chlorpromazine on the Oxidation of D-Amino-Acid in the Diencephalon Part of the Brain

1956 • 71 citations

INDUCED THIAMINE (VITAMIN B1) DEFICIENCY AND THE THIAMINE REQUIREMENT OF MAN

1942 • 70 citations

The Vitamin-Sparing Action of Sorbitol

1957 • 69 citations

PANTOTHENIC ACID AND THE FILTRATE (CHICK ANTI-DERMATITIS) FACTOR

1939 • 68 citations

Studies on the metabolism of pyruvic acid in normal and vitamin B1-deficient states

1939 • 67 citations

Thiamine in nerve membranes

1972 • 67 citations

Properties of a Specific Protease for Pyridoxal Enzymes and Its Biological Role

1972 • 64 citations

An anti-vitamin B6 action of l-penicillamine

1957 • 63 citations

Crystalline Factor I

1938 • 63 citations

A new enzyme that specifically inactivates apo-protein of pyridoxal enzymes

1971 • 62 citations

Pantothenic Acid. II. Its Concentration and Purification from Liver

1938 • 61 citations

Pathogenesis of experimental arteriosclerosis in pyridoxine deficiency; with notes on similarities to human arteriosclerosis.

1951 • 61 citations

THE ROLE OF THIAMINE IN NEUROPHYSIOLOGY

1962 • 60 citations

A Membrane-associated Thiamine Triphosphatase from Rat Brain

1972 • 60 citations

A COMPARISON OF THE EFFECTS OF PYRIDOXINE AND PANTOTHENIC ACID DEFICIENCIES ON THE NERVOUS TISSUES OF SWINE

1945 • 60 citations

Ion movements and thiamine in nervous tissue—I Intact nerve preparations

1970 • 60 citations

The inhibitory action of cystathionine

1966 • 60 citations

Distribution of thiamine phosphate esters in normal and thiamine-deficient brain

1970 • 60 citations

Pantothenic Acid Deficiency Induced in Human Subjects.

1954 • 59 citations

Sensory Neuron Degeneration in Pigs

1942 • 58 citations

THE PANTOTHENIC ACID REQUIREMENT OF THE CHICK

1939 • 58 citations

Pyridoxin Deficiency in the Rat: Liver L-Cysteic Acid Decarboxylase Activity and Urinary Amino-acids

1953 • 58 citations

Thiamine Deficiency Encephalopathy in Cats

1956 • 58 citations

Quelques relations entre le phosphate de pyridoxal et la décarboxylation de l'acide cystéine-sulfinique par divers organes du rat normal ou du rat carencé en vitamine B6

1955 • 57 citations

Effect of experimental thiamine deficiency on the nervous system of the rhesus monkey.

1949 • 56 citations

Polyamine Biosynthesis in Human Fetal Liver and Brain

1974 • 56 citations

Free Amino Acids in Plasma and Tissues of Rats Fed a Vitamin B6-deficient Diet

1964 • 54 citations

Effects of Dietary Depletion of Riboflavin

1949 • 54 citations

The Pathology of Chastek Paralysis in Foxes: A Counterpart of Wernicke's Hemorrhagic Pollioencephalitis of Man.

1942 • 54 citations

A Deficiency Disease of Foxes Produced by Feeding Fish

1941 • 54 citations

SOME EFFECTS OF DIETARY VITAMIN B₆ DEFICIENCY AND 4‐DEOXYPYRIDOXINE ON γ‐AMINOBUTYRIC ACID METABOLISM IN RAT BRAIN

1972 • 53 citations

Effect of electrical stimulation on the influx and efflux of taurine in brain slices of newborn and adult rats

1972 • 53 citations

Distribution and Phosphorylation of Oxythiamine in Rat Tissues

1963 • 53 citations

Synthesis of Taurine and Isethionic Acid by Dog Heart Slices

1962 • 52 citations

PYRIDOXAL PHOSPHATE AND GLUTAMATE DECARBOXYLASE IN SUBCELLULAR PARTICLES OF MOUSE BRAIN AND THEIR RELATIONSHIP TO CONVULSIONS¹

1973 • 52 citations

<scp>l</scp>-Cystathionine in the urine of pyridoxine-deficient rats

1957 • 51 citations

PANTOTHENIC ACID DEFICIENCY STUDIES IN DOGS

1942 • 51 citations

Uptake of pyrithiamine by tissue of rats

1961 • 51 citations

Biochemical Pathology of Vitamin B6 Deficiency

1964 • 49 citations

The Pathology of Thiamin, Riboflavin, Pantothenic Acid and Niacin Deficiencies in the Chick

1972 • 49 citations

Vascular permeability to horseradish peroxidase in brainstem lesions of thiamine-deficient rats.

1972 • 49 citations

Thyroid Hormone Induction of α-Glycerophosphate Dehydrogenase in Rats of Different Ages

1966 • 49 citations

SOME REGIONAL PATHOLOGIC AND METABOLIC CONSEQUENCES IN MOUSE BRAIN OF PYRITHIAMINE-INDUCED THIAMINE DEFICIENCY

1970 • 49 citations

Pyridoxine Effects on Cystathionine Synthase in Rat Liver

1970 • 49 citations

SIGNIFICANCE OF BIOCHEMICAL LESIONS IN THE PYRUVATE OXIDASE SYSTEM*

1953 • 49 citations

Glutamic–oxaloacetic transaminase of cauliflower. 1. Purification and specificity

1961 • 48 citations

DESOXYPYRIDOXINE OBSERVATIONS IN “ACUTE PYRIDOXINE DEFICIENCY”

1950 • 48 citations

THE QUANTITATIVE HISTOCHEMICAL DISTRIBUTION OF THIAMINE IN DEFICIENT RAT BRAIN*

1961 • 48 citations

Regulation of riboflavin-metabolizing enzymes in riboflavin deficiency

1969 • 48 citations

Effects of thiamin deficiency on myocardial metabolism in intact dogs

1953 • 48 citations

An Experiment on Human Vitamin B ₆ Deprivation

1948 • 47 citations

Effects of iron, riboflavin and iodide deficiencies on hepatic drug-metabolizing enzyme systems.

1970 • 47 citations

THE RELATIONSHIP OF COENZYME A TO LIPIDE SYNTHESIS

1953 • 47 citations

Vitamin B6 Metabolism in Infants and Children

1964 • 46 citations

Toward the Conquest of Beriberi

1961 • 46 citations

The Pathology of Pyridoxine Deficiency in Chicks

1972 • 46 citations

Vitamins and Coenzymes.

1964 • 45 citations

OCCIDENTAL BERIBERI WITH CARDIOVASCULAR MANIFESTATIONS

1940 • 44 citations

Répercussion d'une carence en vitamine B6 sur le métabolisme de l'acide L-cystéinesulfinique, in vitro et in vivo, chez le rat

1954 • 44 citations

PRODUCTION OF ACETYLCHOLINE IN RAT BRAIN FOLLOWING THIAMINE DEPRIVATION AND TREATMENT WITH THIAMINE ANTAGONISTS¹²

1969 • 43 citations

Studies of the Mechanism of Pyridoxine-Responsive Homocystinuria

1972 • 43 citations

AN ENZYMATIC STUDY OF THE MODE OF ACTION OF PYRITHIAMINE (NEOPYRITHIAMINE)

1951 • 43 citations

SOME EFFECTS OF DIETARY VITAMIN B₆ DEFICIENCY ON γ‐AMINOBUTYRIC ACID METABOLISM IN DEVELOPING RAT BRAIN

1972 • 43 citations

Flavoenzyme Catalysis

1970 • 43 citations

The Rapid Induction of Human Riboflavin Deficiency with Galactoflavin *

1964 • 42 citations

The Neuropathology of Experimental Vitamin B6Deficiency in Monkeys

1956 • 42 citations

Taurine and Isethionic Acid: Distribution and Interconversion in the Rat

1972 • 42 citations

Thiamine Release from Nerve Membranes by Tetrodotoxin

1969 • 42 citations

THE EFFECT OF A NUTRITIONAL PYRIDOXINE DEFICIENCY ON FREE AMINO ACIDS AND RELATED SUBSTANCES IN MOUSE BRAIN*

1967 • 41 citations

Pyridoxine-responsive genetic disease.

1971 • 41 citations

Hemorrhagic Adrenal Necrosis in Rats on Deficient Diets

1939 • 41 citations

THE PERSISTENCE OF TAURINE IN THE BRAINS OF PYRIDOXINE-DEFICIENT RATS

1957 • 41 citations

Studies on the Interrelationship between Methionine and Vitamin B6

1952 • 40 citations

Selective Metabolic and Chemotherapeutic Effects of Vitamin B6 Antimetabolites

1964 • 40 citations

Distribution of glutathione reductase and detection of glutathione-cystine transhydrogenase in rat tissues

1968 • 40 citations

THE ROLE OF THIAMINE IN NERVOUS TISSUE: EFFECT OF ANTIMETABOLITES OF THE VITAMIN ON CONDUCTION IN MAMMALIAN NONMYELINATED NERVE FIBERS.

1965 • 39 citations

REVIEW ARTICLE

1954 • 38 citations

THE ELECTROCARDIOGRAM IN CHRONIC THIAMINE DEFICIENCY IN RATS

1945 • 38 citations

Biochemistry and the Central Nervous System

1967 • 38 citations

The role of thiamine nervous tissue: The mechanism of action of pyrithiamine

1968 • 38 citations

The enzymatic synthesis of triphosphotiamin

1968 • 37 citations

TOWARD THE CONQUEST OF BERIBERI

1961 • 37 citations

The mode of action of pyrithiamine as an inductor of thiamine deficiency

1958 • 37 citations

Relationships between pyridoxal phosphate availability, activity of vitamin B6-dependent enzymes and convulsions

1971 • 36 citations

Effect of Pyridoxine Deficiency on Reproduction in the Rat

1951 • 36 citations

Studies of the development of congenital anomalies in embryos of riboflavin-deficient, galactoflavin fed rats. I. Growth and embryologic pathology

1968 • 36 citations

The biochemical lesion in vitamin B1 deficiency. Application of modern biochemical analysis in its diagnosis.

1936 • 36 citations

Thiamine Deficiency: Biochemical Lesions and Their Clinical Significance.

1967 • 36 citations

Vitamin B6-Dependency Syndromes

1969 • 36 citations

Development of Myocardial Necrosis and Absence of Nerve Degeneration in Thiamine Deficiency in Pigs.

1943 • 35 citations

Graded levels of pyridoxine in the rat diet during gestation and the physical and neuromotor development of offspring

1973 • 34 citations

TRANS‐SULPHURATION IN PRIMATE BRAIN: REGIONAL DISTRIBUTION OF CYSTATHIONINE SYNTHASE, CYSTATHIONINE AND TAURINE IN THE BRAIN OF THE RHESUS MONKEY AT VARIOUS STAGES OF DEVELOPMENT

1970 • 33 citations

THE EFFECTS OF PYRIDOXINE DEFICIENCY AND OF CALORIC RESTRICTION ON LIPIDS IN THE DEVELOPING RAT BRAIN¹

1971 • 33 citations

Further Observations of Riboflavin Deficiency in the Dog

1941 • 33 citations

Cerebral Lipids and Amino Acids in the Vitamin B6-deficient Suckling Rat

1972 • 33 citations

Some Histopathologic Observations on Chicks Deficient in the Chick Antidermatitis Factor or Pantothenic Acid

1939 • 32 citations

ACTIVATION OF PURIFIED GLUTAMIC—ASPARTIC APOTRANSAMINASE BY CRYSTALLINE PYRIDOXAMINE PHOSPHATE

1952 • 32 citations

Experimental mammalian teratogenesis, a study of galactoflavin‐induced hydrocephalus in mice

1963 • 31 citations

Pantothenic Acid. VII. Partial and Total Synthesis Studies

1940 • 31 citations

THE FLUORESCENT MICROSCOPIC LOCALIZATION OF THIAMINE IN NERVOUS TISSUE

1968 • 31 citations

BRAIN 4‐AMINOBUTYRATE

1968 • 30 citations

COMPOSITION OF MYELIN LIPIDS AND SYNTHESIS OF 3‐KETODIHYDROSPHINGOSINE IN THE VITAMIN B₆‐DEFICIENT DEVELOPING RAT¹

1973 • 30 citations

Cysteine sulfinic acid decarboxylase in rat brain: Effect of vitamin B6 deficiency on soluble and particulate components

1975 • 30 citations

The Occurrence of a Pellagrous-Like Syndrome in Chicks

1930 • 30 citations

The production and study of cardiac failure in thiamin-deficient dogs

1941 • 29 citations

Cystine metabolism in vitamin B6 deficiency: Evidence of muliple taurine pools

1971 • 29 citations

Cellular Growth during Prenatal and Early Postnatal Periods in Progeny of Pyridoxine-deficient Rats

1973 • 29 citations

STUDIES ON THE STRUCTURE OF THE CHICK ANTIDERMATITIS FACTOR

1939 • 29 citations

Vitamin B6 Deficiency in Chicks

1939 • 29 citations

THE EFFECT OF PANTOTHENIC ACID DEFICIENCY ON GASTRIC SECRETION AND MOTILITY

1955 • 28 citations

SPARING ACTION OF FAT ON THE ANTINEURITIC VITAMIN

1928 • 28 citations

Effect of thiamine deficiency on the competence of the blood-brain barrier to albumin labeled with fluorescent dyes.

1971 • 28 citations

The Vitamin B6 Requirement of the Male Rat as Determined by Behavioral Patterns, Brain Pyridoxal Phosphate and Nucleic Acid Composition and Erythrocyte Alanine Aminotransferase Activity

1973 • 28 citations

Congenital Malformations as Related to Deficiencies of Riboflavin and Vitamin B12, Source of Protein, Calcium to Phosphorus Ratio and Skeletal Phosphorus Metabolism ,

1954 • 27 citations

Pantothenic Acid Studies. VI. A Biologically Active Conjugate of Pantothenic Acid

1949 • 27 citations

Glutamic–oxaloacetic transaminase of cauliflower. 2. Kinetics and mechanism of action

1961 • 27 citations

Metabolism of l-35S-methionine in vitamin B6 deficiency: Observations on cystathioninuria

1970 • 27 citations

The Effect of Administration of Pantothenic Acid on the Histopathology of the Filtrate Factor Deficiency State in Rats

1940 • 27 citations

Transsulfuration in Fetal and Postnatal Mammalian Liver and Brain

1972 • 27 citations

EFFECT OF PYRIDOXINE DEFICIENCY ON AROMATIC <scp>l</scp>‐AMINO ACID DECARBOXYLASE IN THE DEVELOPING RAT LIVER AND BRAIN

1968 • 27 citations

Cerebral Acetylcholine in Thiamine Deficiency

1970 • 26 citations

Vitamin B6 (Pyridoxine) in the Nutrition of the Pig

1942 • 26 citations

Primate Nutrition II. Riboflavin Deficiency in the Cebus Monkey and Its Diagnosis

1952 • 26 citations

Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines—III

1967 • 25 citations

THE METABOLISM IN VITRO OF CARDIAC MUSCLE IN PANTOTHENIC ACID DEFICIENCY

1951 • 24 citations

Pyridoxine Deficiency in Chicks

1942 • 24 citations

Studies on the Vitamin B1 Requirements of Growing Chicks

1938 • 24 citations

Controlled trial of hydroxocobalamin and riboflavine in Nigerian ataxic neuropathy

1970 • 23 citations

Biochemical Studies on Experimental Congenital Malformations: Flavin Nucleotides and Folic Acid in Fetuses and Livers from Normal and Riboflavin-deficient Rats

1962 • 23 citations

Flavins and monoamine oxidase activity in the brain, liver and kidney of the developing rat

1969 • 23 citations

Development of cardiac lesions in thiamine-deficient rats.

1944 • 23 citations

Glycine Metabolism in Vitamin B6-deficient and Deoxypyridoxine-treated Rats

1969 • 23 citations

Thiamine Monophosphate, a Normal Constituent of Rat Plasma

1968 • 23 citations

NUTRITIONAL DERMATOSES IN THE RAT VI. THE EFFECT OF PANTOTHENIC ACID DEFICIENCY

1942 • 23 citations

Enzyme studies in thiamine deficiency.

1968 • 23 citations

Vitamin B6 in human nutrition: a critique and an object lesson.

1954 • 22 citations

STUDIES ON VITAMIN B6

1953 • 22 citations

CLINICAL ASPECTS OF DIETARY DEPLETION OF RIBOFLAVIN

1951 • 22 citations

Studies on Pyridoxine Deficiency in Rats

1968 • 22 citations

Studies of Pantothenic Acid Deficiency in Dogs

1944 • 22 citations

The Effects of Galactoflavin on Riboflavin Enzymes and Coenzymes

1964 • 22 citations

Neuropharmacological comparison of cystathionine, cysteine, homoserine and alpha-ketobutyric acid in cats

1970 • 22 citations

The Cellular Approach to the Determination of Pyridoxine Requirements in Pregnant and Nonpregnant Rats

1971 • 22 citations

Effect of a high-fat diet on the excretion of bisulphite-binding substances in the urine of rats deficient in vitamin B1

1940 • 21 citations

Nutrition in India.

1952 • 21 citations

Studies of Pantothenic Acid Metabolism

1956 • 21 citations

A study of l-[14C]cystathionine metabolism in the brain, kidney, and liver of pyridoxine-deficient rats

1971 • 20 citations

Nutritional Studies with the Guinea Pig

1954 • 19 citations

Effects of pyrithiamine and oxythiamine on the thiamine content of tissues and blood pyruvate in mice

1956 • 19 citations

REGIONAL DISTRIBUTION OF GLUTAMIC ACID DECARBOXYLASE IN THE DEVELOPING BRAIN OF THE PYRIDOXINE‐DEFICIENT RAT

1973 • 19 citations

Vitamin B₁ deficiency in the rat's brain

1935 • 19 citations

Hemorrhagic Cortical Necrosis of Adrenals in Rats on Deficient Diets

1939 • 19 citations

Effect of Pyridoxine Deficiency upon Valine Incorporation into Tissue Proteins of the Rat

1964 • 19 citations

Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines—II

1966 • 18 citations

Homolanthionine synthesis by human liver cystathionase

1971 • 18 citations

Taurine intolerance in psoriasis.

1966 • 17 citations

Studies on the Vitamin B1 Requirements Of Growing Rats

1938 • 17 citations

Thiamine-sparing Action of Sorbitol in Rats and Mice

1959 • 17 citations

Purification and properties of human brain mitochondrial monoamine oxidase.

1970 • 17 citations

Polyamine biosynthesis and vitamin B6 deficiency Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase☆

1974 • 17 citations

Pathologic Changes Associated with Riboflavin Deficiency in the Mouse

1942 • 17 citations

Osteoporotic bone disease in the pyridoxine-deficient rat

1972 • 16 citations

Cortical-evoked Responses in Pyridoxine-deficient Rats

1973 • 16 citations

Studies on the Physiological Functions of Thiamine

1962 • 16 citations

Taurine Intolerance in Psoriasis**From the Graduate School of Nutrition, Cornell University, Sage Hospital, Ithaca, New York.

1966 • 16 citations

Brain cystathionine synthase: Vitamin-B6 requirement for its enzymic reaction and changes in enzymic activity during early development of rats

1971 • 16 citations

Influences of Pyridoxine Derivatives on the Biosynthesis and Stability of Pyridoxal Phosphate Enzymes

1971 • 15 citations

Identification of flavin in the purified beef brain mitochondrial monoamine oxidase

1969 • 15 citations

Homocystinuria: Observations on the Biosynthesis of Cystathionine and Homolanthionine

1971 • 15 citations

INCORPORATION OF PERIPHERALLY ADMINISTERED RIBOFLAVINE INTO FLAVINE NUCLEOTIDES IN THE BRAIN

1967 • 15 citations

Pyridoxine Deficiency and Pyridoxine Dependency in Infants and Children

1964 • 15 citations

The Lack of Nerve Degeneration in Uncomplicated Vitamin B1 Deficiency in the Chick and the Rat

1938 • 15 citations

Pantothenic Acid. V. Evidence for Structure of Non-β-Alanine Portion

1940 • 15 citations

Perinatal development of enzymes synthesizing FMN and FAD

1969 • 14 citations

Hepatic cystathionase: Immunochemical and electrophoretic studies of the human and rat forms

1972 • 14 citations

Riboflavin deficiency in swine, with special reference to the occurrence of cataracts.

1944 • 14 citations

Bacterial conversion of pantothenic acid into coenzyme A (acetylation) and its relation to pyruvic oxidation.

1947 • 14 citations

Neuropathologic Studies of Acute and Chronic Thiamine Deficiencies and of Inanition

1945 • 13 citations

PROBLEMS OF THIAMINE DEFICIENCY STATES AND THEIR AMELIORATION

1962 • 13 citations

Riboflavin Deficiency and Congenital Malformations

1975 • 13 citations

The clinical and biochemical significance of taurine excretion in psoriasis.

1962 • 13 citations

Morphologic Changes Associated With Pantothenic Acid Deficiency in the Mouse&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;

1941 • 13 citations

Regulation of ornithine decarboxylase synthesis effect of a nutritional deficiency of vitamin B6

1974 • 12 citations

Glial α-Glycerophosphate Dehydrogenase and Central Myelination

1967 • 12 citations

THE PREVENTION OF SENSORY NEURON DEGENERATION IN THE PIG, WITH SPECIAL REFERENCE TO THE RÔLE OF VARIOUS LIVER FRACTIONS 1

1942 • 12 citations

35S 2-Hydroxyethanesulfonic Acid (Isethionic Acid) in Urine of Human Subjects Given 35S Taurine.

1967 • 12 citations

The effect of flavin adenine dinucleotide on the electroencephalogram modified by chlorpromazine

1960 • 11 citations

Frequency Analysis of Electroencephalograms and Latency of Photically Induced Average Evoked Responses in Children with Ariboflavinosis (Preliminary Report)

1968 • 11 citations

Effect of thiamine analogs on the electrical activity of the rabbit vagus nerve

1965 • 10 citations

Effect of diets rich in protein upon rats deprived of vitamin B1

1941 • 10 citations

Burning-Feet Syndrome: Case Due to Malabsorption and Responding to Riboflavine

1970 • 9 citations

Pantothenic Acid Deficiency and Its Effect on the Integrity and Functions of the Intestines

1958 • 9 citations

Transport and Storage of 14G-Riboflavin in the Retina and Liver of Rats.

1967 • 9 citations

The uptake of pyrithiamine by cerebral tissue

1961 • 9 citations

The effect of thiamine deficiency in rats and pigeons on the content of materials with acetylcholine-like activity in brain, heart and skeletal muscle.

1966 • 9 citations

The Clinical and Biochemical Significance of Taurine Excretion in Psoriasis**From the Graduate School of Nutrition, Cornell University, Ithaca, N.Y. This study was supported by the research grant A-5690 (C1) from the National Institutes of Health, Public Health Service, Bethesda, Maryland.

1962 • 9 citations

Inhibition of flavoenzymes by phenothiazines.

1968 • 8 citations

EXPERIENCE IN THE ETIOLOGY AND PREVENTION OF THIAMINE DEFICIENCY IN THE PHILIPPINE ISLANDS

1962 • 8 citations

Electroencephalographic and Nerve-Conduction Studies in Experimental Vitamin B6, Deficiency in Adults

1969 • 8 citations

Duodenitis and duodenal ulcers produced in rats by pantothenic acid deficiency.

1959 • 8 citations

The in vivo effects of pyrithiamine and oxythiamine in the rat.

1956 • 7 citations

Induction of a Specific Enzyme Inadequacy in Infant Rats by the Use of a Homologue of Riboflavin

1971 • 7 citations

The effect of dietary vitamin B6 deficiency on the development of the γ-aminobutyrate shunt in rat brain

1972 • 7 citations

Biochemical Role of Thiamine Triphosphoric Acid Ester

1966 • 7 citations

Effect of pyridoxine deficiency on nucleic acid and protein contents of brain and liver in rats.

1971 • 7 citations

A Histopathologic Study of Chicks Deficient in Pantothenic Acid

1949 • 6 citations

Effect of Riboflavin-low Diets upon Nerves, Growth, and Reproduction in the Rat.

1939 • 6 citations

Effects of Flavin Monosulphate and Flavin Adenine Dinucleotide on the Electroencephalogram

1958 • 5 citations

Effect of prolonged pantothenic acid deprivation upon cholesterol synthesis in the rat

1954 • 5 citations

In vivo incorporation of L-(U- 14 C) lysine and L-(U- 14 C) leucine into brain proteins in pyridoxine deficiency.

1971 • 5 citations

Methionine load test in pyridoxine deficiency.

1972 • 5 citations

Die Vitamine in der Neurologie

2015 • 5 citations

The Effect of a Vitaminlike Homolog of Riboflavin on Succinic Acid Dehydrogenase Activity of Brain

1970 • 4 citations

Effects of Pyrithiamin Injection into the Brain of Rats

1970 • 4 citations

EFFECTS OF FLAVINS ON THE ELECTROENCEPHALOGRAM

1959 • 4 citations

The oxidation of C14-pyruvate and of C14-ribose in thiamine deficient intact rats.

1967 • 3 citations

Rice enrichment in the Philippines

1954 • 3 citations

Dietary Vitamin B₆ and Enzymes of Methionine Metabolism in Rat Liver

1970 • 3 citations

Protein Synthesis in Vitamin B6 Deficiency in the Rat

1962 • 3 citations

Changes of total flavines in different parts of the rat brain under the influence of oxo-tremorine

1968 • 3 citations

The effects of oxythiamine injection into the brain of rats and a comparison with pyrithiamine similarly injected.

1970 • 2 citations

In vitro biochemical examination of FMN synthesis with the brain homogenate of developing chicken embryo.

1966 • 2 citations

Effect of Certain Nutritional Deficiencies on Various Phosphorus-containing Fractions of the Chick Brain.

1937 • 2 citations

Monoamine oxidase activity and norepinephrine content of organs from rats fed on a vitamin B2-deficient diet.

1971 • 1 citations