Hypermethylation of the caveolin-1 gene promoter in prostate cancer

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

1992 • 3,099 citations

CpG island methylator phenotype in colorectal cancer

1999 • 2,476 citations

Cancer-epigenetics comes of age

1999 • 2,379 citations

Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane

1998 • 1,502 citations

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1994 • 1,205 citations

Caveolins, Liquid-Ordered Domains, and Signal Transduction

1999 • 1,016 citations

Reduction of caveolin and caveolae in oncogenically transformed cells.

1995 • 505 citations

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

1998 • 473 citations

Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

1998 • 435 citations

Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts.

1992 • 369 citations

Caveolin Isoforms Differ in Their N-terminal Protein Sequence and Subcellular Distribution. IDENTIFICATION AND EPITOPE MAPPING OF AN ISOFORM-SPECIFIC MONOCLONAL ANTIBODY PROBE

1995 • 362 citations

Increased Cytosine DNA-Methyltransferase Activity During Colon Cancer Progression

1993 • 315 citations

Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol

1997 • 256 citations

Prostate Specific Antigen Levels After Radical Prostatectomy in Patients with Organ Confined and Locally Extensive Prostate Cancer

1992 • 232 citations

Genes encoding human caveolin‐1 and ‐2 are co‐localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

1998 • 227 citations

Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells

1998 • 186 citations

Molecular Genetics of the Caveolin Gene Family: Implications for Human Cancers, Diabetes, Alzheimer Disease, and Muscular Dystrophy

1998 • 184 citations

Reduction of Caveolin 1 Gene Expression in Lung Carcinoma Cell Lines

1999 • 159 citations

Sequence and detailed organization of the human caveolin‐1 and ‐2 genes located near the D7S522 locus (7q31.1)

1999 • 151 citations

Caveolae, transmembrane signalling and cellular transformation

1995 • 139 citations

Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines

1999 • 124 citations

Chromosomal abnormalities and related events in prostate cancer

1992 • 120 citations

Chromosomal clues to the development of prostate tumors

1999 • 89 citations

Review of allelic loss and gain in prostate cancer

1996 • 73 citations

Visualization of caveolin‐1, a caveolar marker protein, in living cells using green fluorescent protein (GFP) chimeras

1999 • 65 citations

Analysis of cyclin-dependent kinase inhibitor expression and methylation patterns in human prostate cancers

2000 • 64 citations

Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines

1999 • 60 citations

Chromosome 7q deletions: Observations on 13 malignant tumors

1993 • 44 citations

Chromosome 7 Abnormalities in Prostate Cancer Detected by Dual-Color Fluorescence In Situ Hybridization

1998 • 37 citations

Concentration of Caveolin-1 in the Cleavage Furrow as Revealed by Time-Lapse Analysis

2000 • 25 citations