A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production.

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

The Molecular Genetics of Cancer

1987 • 1,729 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Adsorbents for affinity chromatography. Use of N-hydroxysuccinimide esters of agarose

1972 • 463 citations

Acceleration of nucleic acid hybridization rate by polyethylene glycol

1986 • 383 citations

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.

1988 • 367 citations

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells

1987 • 355 citations

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1985 • 273 citations

Malignant transformation of a growth factor-dependent myeloid cell line by Abelson virus without evidence of an autocrine mechanism

1985 • 272 citations

Constitutive production of a unique lymphokine (IL 3) by the WEHI-3 cell line.

1982 • 227 citations

Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes

1985 • 176 citations

Conditioned tumorigenicity of activated oncogenes.

1986 • 173 citations

Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells

1984 • 159 citations

v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation

1986 • 156 citations

Biological activities of v-myc and rearranged c-myc oncogenes in rat fibroblast cells in culture.

1984 • 132 citations

Transforming ras oncogenes and multistage carcinogenesis

1985 • 109 citations

v-mil induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages

1986 • 100 citations

Interleukin-3-dependent expression of the c-myc and c-fos proto-oncogenes in hemopoietic cell lines.

1986 • 89 citations

Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon.

1985 • 50 citations

ras gene activation in a minor proportion of the blast population in acute myeloid leukemia.

1987 • 47 citations

Myeloid cell transformation by ras-containing murine sarcoma viruses.

1985 • 40 citations

Spontaneous, in vitro, Malignant Transformation of a Basophil/Mast Cell Line

1983 • 39 citations

Cellular Oncogenes and Multistep Carcinogenesis

2019 • 38 citations

Relapse cell population differs from acute onset clone as shown by absence of the initially activated N-ras oncogene in a patient with acute myelomonocytic leukemia

1988 • 31 citations

Induction of clonal monocyte-macrophage tumors in vivo by a mouse c-myc retrovirus: rearrangement of the CSF-1 gene as a secondary transforming event.

1987 • 29 citations

Mature murine B lymphocytes immortalized by Kirsten sarcoma virus

1986 • 21 citations

Infection of Immune Mast Cells by Harvey Sarcoma Virus: Immortalization Without Loss of Requirement for Interleukin-3

1985 • 17 citations

Growth-factor-independent proliferation in vitro and tumorigenicity in vivo are associated in basophil/mast-cell lines and their somatic hybrids

1985 • 13 citations

Glycine-cysteine substitution at codon 13 of the N-ras proto-oncogene in a human T cell non-Hodgkin's lymphoma.

1987 • 6 citations