Pulmonary Embolism

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

Trends in the Incidence of Deep Vein Thrombosis and Pulmonary Embolism

1998 • 2,620 citations

A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study

1991 • 1,994 citations

A Clinical Trial of Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep-Vein Thrombosis

1998 • 1,679 citations

Low-Molecular-Weight Heparins

1997 • 1,529 citations

The Management of Thrombosis in the Antiphospholipid-Antibody Syndrome

1995 • 1,467 citations

ANTICOAGULANT DRUGS IN THE TREATMENT OF PULMONARY EMBOLISM

1960 • 1,334 citations

Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaborative study (ISCOAT)

1996 • 1,331 citations

Reduction in Fatal Pulmonary Embolism and Venous Thrombosis by Perioperative Administration of Subcutaneous Heparin

1988 • 1,321 citations

World distribution of factor V Leiden

1995 • 1,184 citations

Resistance to Activated Protein C as a Basis for Venous Thrombosis

1994 • 1,148 citations

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation

1994 • 1,065 citations

Mutation in the Gene Coding for Coagulation Factor V and the Risk of Myocardial Infarction, Stroke, and Venous Thrombosis in Apparently Healthy Men

1995 • 1,060 citations

The Clinical Course of Pulmonary Embolism

1992 • 1,045 citations

Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis

1996 • 1,034 citations

Management Strategies and Determinants of Outcome in Acute Major Pulmonary Embolism: Results of a Multicenter Registry

1997 • 1,025 citations

A Comparison of Six Weeks with Six Months of Oral Anticoagulant Therapy after a First Episode of Venous Thromboembolism

1995 • 950 citations

A 14-year study of heparin-induced thrombocytopenia

1996 • 898 citations

Detection of Deep-Vein Thrombosis by Real-Time B-Mode Ultrasonography

1989 • 883 citations

Risk of venous thromboembolism in users of hormone replacement therapy

1996 • 827 citations

Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion

1993 • 824 citations

A Comparison of Low-Dose Heparin with Low-Molecular-Weight Heparin as Prophylaxis against Venous Thromboembolism after Major Trauma

1996 • 791 citations

Low-Molecular-Weight Heparin in the Treatment of Patients with Venous Thromboembolism

1997 • 785 citations

Clinical, Laboratory, Roentgenographic, and Electrocardiographic Findings in Patients with Acute Pulmonary Embolism and No Pre-Existing Cardiac or Pulmonary Disease

1991 • 781 citations

A Comparison of Low-Molecular-Weight Heparin with Unfractionated Heparin for Acute Pulmonary Embolism

1997 • 776 citations

Risk of idiopathic cardiovascular death and rionfatal venous thromboembolism in women using oral contraceptives with differing progestagen components

1995 • 747 citations

The Weight-based Heparin Dosing Nomogram Compared with a Standard Care Nomogram

1993 • 746 citations

Regional Right Ventricular Dysfunction Detected by Echocardiography in Acute Pulmonary Embolism

1996 • 729 citations

Deep-Vein Thrombosis and the Incidence of Subsequent Symptomatic Cancer

1992 • 689 citations

Complications and validity of pulmonary angiography in acute pulmonary embolism.

1992 • 675 citations

Pulmonary Angiography, Ventilation Lung Scanning, and Venography for Clinically Suspected Pulmonary Embolism with Abnormal Perfusion Lung Scan

1983 • 666 citations

The antiphospholipid syndrome: ten years on

1993 • 640 citations

The Duration of Oral Anticoagulant Therapy after a Second Episode of Venous Thromboembolism

1997 • 618 citations

Risk of hospital admission for idiopathic venous thromboembolism among users of postmenopausal oestrogens

1996 • 606 citations

Prospective study of exogenous hormones and risk of pulmonary embolism in women

1996 • 580 citations

Diagnosis of pulmonary embolism with spiral CT: comparison with pulmonary angiography and scintigraphy.

1996 • 565 citations

Echocardiography Doppler in pulmonary embolism: Right ventricular dysfunction as a predictor of mortality rate

1997 • 543 citations

Collaborative overview of randomised trials of antiplatelet therapy - III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients

1994 • 507 citations

Acenocoumarol and Heparin Compared with Acenocoumarol Alone in the Initial Treatment of Proximal-Vein Thrombosis

1992 • 487 citations

Venous thromboembolic disease and combined oral contraceptives: results of international multicentre case-control study

1995 • 486 citations

Diagnosis of Pulmonary Embolism with Magnetic Resonance Angiography

1997 • 481 citations

The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia

1997 • 478 citations

Streptokinase and heparin versus heparin alone in massive pulmonary embolism: A randomized controlled trial

1995 • 476 citations

Low-Molecular-Weight Heparin (Enoxaparin) as Prophylaxis against Venous Thromboembolism after Total Hip Replacement

1996 • 474 citations

Association Between Thrombolytic Treatment and the Prognosis of Hemodynamically Stable Patients With Major Pulmonary Embolism

1997 • 468 citations

Deficiencies of Coagulation-Inhibiting and Fibrinolytic Proteins in Outpatients with Deep-Vein Thrombosis

1990 • 456 citations

Heparin-Induced Thrombocytopenia (HIT): An Overview of 230 Patients Treated with Orgaran (Org 10172)

1993 • 452 citations

Risk of deep-venous thrombosis after hospital discharge in patients having undergone total hip replacement: double-blind randomised comparison of enoxaparin versus placebo

1996 • 451 citations

Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V

1994 • 446 citations

Effect of different progestagens in low oestrogen oral contraceptives on venous thromboembolic disease

1995 • 446 citations

Homocysteine and Thrombotic Disease

1997 • 436 citations

Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C.

1994 • 430 citations

Echocardiographic Pattern of Acute Cor Pulmonale

1997 • 428 citations

Prognostic significance of right ventricular afterload stress detected by echocardiography in patients with clinically suspected pulmonary embolism.

1997 • 414 citations

Plasma Measurement of D-Dimer as Diagnostic Aid in Suspected Venous Thromboembolism: An Overview

1994 • 396 citations

Venous Thromboembolism during Pregnancy

1996 • 394 citations

The Risk of Recurrent Venous Thromboembolism in Patients with an Arg⁵⁰⁶→Gln Mutation in the Gene for Factor V (Factor V Leiden)

1997 • 380 citations

Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). The PIOPED Investigators

1990 • 369 citations

Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy

1997 • 364 citations

Functional and immunologic protein S levels are decreased during pregnancy

1986 • 347 citations

Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second‐ and third‐generation oral contraceptives

1997 • 337 citations

Population-based study of risk of venous thromboembolism associated with various oral contraceptives

1997 • 335 citations

Accuracy of Ultrasound for the Diagnosis of Deep Venous Thrombosis in Asymptomatic Patients after Orthopedic Surgery

1995 • 325 citations

Prevention of Deep Vein Thrombosis after Elective Hip Surgery

1991 • 311 citations

Prevalence of deep venous thrombosis among patients in medical intensive care

1995 • 311 citations

Diagnostic Utility of Ultrasonography of Leg Veins in Patients Suspected of Having Pulmonary Embolism

1997 • 302 citations

The ECG in Pulmonary Embolism

1997 • 293 citations

Factor V Leiden Mutation and the Risks for Thromboembolic Disease: A Clinical Perspective

1997 • 278 citations

Postoperative Pulmonary Embolism After Hospital Discharge

1992 • 277 citations

Factor V Leiden and Risks of Recurrent Idiopathic Venous Thromboembolism

1995 • 251 citations

Efficacy and safety of enoxaparinversus unfractionated heparin for prevention of deep vein thrombosis in elective cancer surgery: A double-blind randomized multicentre trial with venographic assessment

1997 • 251 citations

Thromboprophylaxis with Low Molecular Weight Heparin (Fragmin) in High Risk Pregnancies

1997 • 242 citations

Deep venous thrombosis and occult malignancy: an epidemiological study

1994 • 236 citations

Prevention of Venous Thromboembolism after Knee Arthroplasty

1996 • 234 citations

Monitoring Warfarin Therapy in Patients with Lupus Anticoagulants

1997 • 217 citations

Medical compared with surgical treatment for massive pulmonary embolism

1994 • 209 citations

Relation of Duration of Symptoms With Response to Thrombolytic Therapy in Pulmonary Embolism

1997 • 207 citations

A 30-year survey of pulmonary embolism verified at autopsy: An analysis of 1274 surgical patients

1985 • 198 citations

Home Prothrombin Time Monitoring after the Initiation of Warfarin Therapy

1989 • 196 citations

Arterial Blood Gas Analysis in the Assessment of Suspected Acute Pulmonary Embolism

1996 • 190 citations

Reduction of Mortality in General Medical In-patients by Low-Dose Heparin Prophylaxis

1982 • 190 citations

The Incidence of Symptomatic Venous Thromboembolism During and After Prophylaxis With Enoxaparin<subtitle>A Multi-institutional Cohort Study of Patients Who Underwent Hip or Knee Arthroplasty</subtitle>

1998 • 187 citations

Alveolar-Arterial Oxygen Gradient in the Assessment of Acute Pulmonary Embolism

1995 • 179 citations

Prolonged Thromboprophylaxis Following Hip Replacement Surgery – Results of a Double-blind, Prospective, Randomised, Placebo-controlled Study with Dalteparin (Fragmin®)

1997 • 175 citations

Why does prophylaxis with external pneumatic compression for deep vein thrombosis fail?

1992 • 173 citations

Ultrasonographic Screening before Hospital Discharge for Deep Venous Thrombosis after Arthroplasty: The Post-Arthroplasty Screening Study: A Randomized, Controlled Trial

1997 • 164 citations

Pulmonary Physiology during Pulmonary Embolism

1992 • 163 citations

EFFECTS OF EXTERNAL PNEUMATIC INTERMITTENT COMPRESSION ON FIBRINOLYSIS IN MAN

1973 • 150 citations

Resistance to activated protein C in healthy women taking oral contraceptives

1995 • 141 citations

Increasing age is a major risk factor for hemorrhagic complications after pulmonary embolism thrombolysis

1997 • 139 citations

Recurrence of venous thromboembolism in patients with familial thrombophilia

1997 • 134 citations

D-dimer testing in suspected venous thromboembolism: an update

1997 • 133 citations

Hyperhomocysteinemia and Deep-Vein Thrombosis A Case-Control Study

1996 • 131 citations

Prevention of Deep Vein Thrombosis following Total Hip Replacement by Low Molecular Weight Heparinoid

1992 • 126 citations

Echocardiographic Evaluation of Pulmonary Embolism and Its Response to Therapeutic Interventions

1992 • 120 citations

Pharmacologic Hemodynamic Support in Massive Pulmonary Embolism

1997 • 115 citations

Thromboembolism coincident with tourniquet deflation during total knee arthroplasty

1993 • 111 citations

Efficacy and Safety of Low Molecular Weight Heparin (Ardeparin Sodium) Compared to Warfarin for the Prevention of Venous Thromboembolism after Total Knee Replacement Surgery: A Double-blind, Dose-ranging Study

1997 • 104 citations

Heparin-Induced thrombocytopenia: IgG-Mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-Induced thrombocytopenia

1996 • 102 citations

A New Treatment for Severe Pulmonary Embolism

1997 • 102 citations

Mechanical Fragmentation and Pharmacologic Thrombolysis in Massive Pulmonary Embolism

1997 • 98 citations

Cancer and venous thromboembolism

1996 • 95 citations

A prospective study of risk factors for pulmonary embolism in women

1997 • 95 citations

Value of ventilation/perfusion scans versus perfusion scans alone in acute pulmonary embolism

1992 • 94 citations

Pulmonary embolism and deep venous thrombosis during pregnancy or oral contraceptive use: Prevalence of factor V Leiden

1996 • 92 citations

Frequent asymptomatic pulmonary embolism in patients with deep venous thrombosis

1994 • 67 citations

The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis in the elderly

1994 • 62 citations

Deep Venous Thrombosis and Lupus Anticoagulant

1996 • 61 citations

A randomized trial comparing activated thromboplastin time with heparin assay in patients with acute venous thromboembolism requiring large daily doses of heparin

1994 • 55 citations

Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation

1996 • 50 citations

Enlargement of the right descending pulmonary artery in pulmonary embolism

1983 • 47 citations

Recent advances in understanding clotting and evaluating patients with recurrent thrombosis

1992 • 39 citations

D-Dimer Determination to Exclude Pulmonary Embolism: a Two-Step Approach Using Latex Assay as a Screening Tool

1994 • 36 citations

Effectiveness of intermittent pneumatic leg compression for preventing deep vein thrombosis after total hip replacement

1990 • 31 citations

Workshop: Anticoagulation clinic care versus routine medical care: A review and interim report

1996 • 24 citations

State-of-the-Art Review: The Preclinical and Clinical Pharmacology of Novastan (Argatroban): A Small-Molecule, Direct Thrombin Inhibitor

1997 • 22 citations

Ardeparin (low-molecular-weight heparin) vs graduated compression stockings for the prevention of venous thromboembolism. A randomized trial in patients undergoing knee surgery

1996 • 21 citations

Long-term experience with transvenous catheter pulmonary embolectomy

1993 • 21 citations

Free-floating thrombus and embolic risk in patients with angiographically confirmed proximal deep venous thrombosis. A prospective study

1997 • 20 citations

Thirty-day case-fatality rates for pulmonary embolism in the elderly

1996 • 18 citations

The low-probability lung scan. A need for change in nomenclature

1995 • 18 citations

Duration of anticoagulant therapy after first episode of venous thrombosis in patients with inherited thrombophilia

1997 • 16 citations

The low-probability lung scan. A potentially lethal reading

1993 • 3 citations