Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for sequencing DNA.

1977 • 7,941 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

A simple method for DNA restriction site mapping

1976 • 1,025 citations

Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries.

1985 • 818 citations

α-Interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences

1985 • 498 citations

Mx protein: Constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus

1986 • 479 citations

Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene

1982 • 464 citations

Shotgun DNA sequencing using cloned DNase I-generated fragments

1981 • 425 citations

Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element.

1987 • 398 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Compilation and analysis of eukaryotic POL II promoter sequences

1986 • 345 citations

Interferon-activated genes

1986 • 301 citations

Interferon response element of the human gene 6-16.

1988 • 292 citations

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

1986 • 252 citations

Interferon induces a unique protein in mouse cells bearing a gene for resistance to influenza virus.

1983 • 247 citations

Exon/intron organization and complete nucleotide sequence of an HLA gene.

1982 • 239 citations

Sendai virus contains overlapping genes expressed from a single mRNA

1983 • 231 citations

Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.

1986 • 185 citations

A 46-nucleotide promoter segment from an IFN-α gene renders an unrelated promoter inducible by virus

1985 • 185 citations

Resistance of mice to mouse-adapted influenza A virus

1962 • 171 citations

Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes.

1984 • 158 citations

Genetically determined, interferon-dependent resistance to influenza virus in mice.

1979 • 158 citations

Host gene influences sensitivity to interferon action selectively for influenza virus

1980 • 154 citations

Structure and expression of cloned murine IFN-α genes

1983 • 154 citations

Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors.

1987 • 141 citations

Genomic characterization of a gamma-interferon-inducible gene (IP-10) and identification of an interferon-inducible hypersensitive site.

1987 • 137 citations

Cell-specific expression of the human complement protein Factor B gene: Evidence for the role of two distinct 5′-flanking elements

1987 • 128 citations

Interferons as Gene Activators

1989 • 124 citations

Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses

1985 • 123 citations

Reversible silencing of enhancers by sequences derived from the human IFN-α promoter

1987 • 119 citations

New inducers revealed by the promoter sequence analysis of two interferon-activated human genes

1987 • 110 citations

Transcriptional activation of the mouse Mx gene by type I interferon.

1986 • 92 citations

Regulation of murine class I genes by interferons is controlled by regions located both 5' and 3' to the transcription initiation site.

1987 • 91 citations

Polyclonal and monoclonal antibodies to the interferon-inducible protein Mx of influenza virus-resistant mice.

1985 • 77 citations

Transport of the Murine Mx Protein into the Nucleus Is Dependent on a Basic Carboxy-Terminal Sequence

1987 • 66 citations

Host gene influence on interferon action in adult mouse hepatocytes: Specificity for influenza virus

1980 • 32 citations

Interferons Increase Transcription of a Major Histocompatibility Class I Gene Via a 5′ Interferon Consensus Sequence

1987 • 15 citations

Structure and nucleotide sequence of the heavy chain gene of HLA-DR

1983 • 6 citations