Transcription Analysis, Physical Mapping, and Molecular Characterization of a Nonclassical Human Leukocyte Antigen Class I Gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Genomic sequencing.

1984 • 8,343 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Plasmid screening at high colony density

1980 • 1,100 citations

Electrophoretic Separations of Large DNA Molecules by Periodic Inversion of the Electric Field

1986 • 920 citations

A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment.

1987 • 515 citations

The natural history of the major histocompatibility complex

1987 • 500 citations

Origin of major histocompatibility complex polymorphism: The trans-species hypothesis

1987 • 450 citations

Genes of the Major Histocompatibility Complex of the Mouse

1983 • 445 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Use of restriction enzymes to detect potential gene sequences in mammalian DNA

1987 • 387 citations

Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes.

1987 • 351 citations

HLA-A and B polymorphisms predate the divergence of humans and chimpanzees

1988 • 341 citations

Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse

1984 • 323 citations

A pseudogene homologous to mouse transplantation antigens: Transplantation antigens are encoded by eight exons that correlate with protein domains

1981 • 320 citations

Unstable β-globin mRNA in mRNA-deficient β0 thalassemia

1981 • 267 citations

Cloning and complete sequence of an HLA-A2 gene: analysis of two HLA-A alleles at the nucleotide level.

1985 • 255 citations

A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17

1980 • 243 citations

Recognition of HLA-B27 and related antigen by a monoclonal antibody

1982 • 240 citations

Nucleotide sequences of chimpanzee MHC class I alleles: evidence for trans-species mode of evolution.

1988 • 240 citations

Exon/intron organization and complete nucleotide sequence of an HLA gene.

1982 • 239 citations

HLA-E. A novel HLA class I gene expressed in resting T lymphocytes.

1988 • 239 citations

Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway.

1986 • 220 citations

Non-methylated CpG-rich islands at the human alpha-globin locus: implications for evolution of the alpha-globin pseudogene.

1987 • 201 citations

Secretion of a transplantation-related antigen

1983 • 150 citations

CG dinucleotide clusters in MHC genes and in 5′ demethylated genes

1984 • 146 citations

Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.

1983 • 136 citations

Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex.

1983 • 131 citations

Megabase-Scale Mapping of the HLA Gene Complex by Pulsed Field Gel Electrophoresis

1987 • 126 citations

Isolation of HLA locus-specific DNA probes from the 3'-untranslated region.

1984 • 120 citations

Biochemical complexity of serum HLA class I molecules

1988 • 117 citations

[35] Strategies for mapping and cloning macroregions of mammalian genomes

1987 • 112 citations

Chromosomal organization of the human major histocompatibility complex class I gene family.

1989 • 112 citations

[32] Preparation of cDNA and the generation of cDNA libraries: Overview

1987 • 94 citations

Searching for coding sequences in the mammalian genome: the H-2K region of the mouse MHC is replete with genes expressed in embryos.

1988 • 89 citations

A cDNA clone containing the entire coding sequence of a mouse H-2Kd histocompatibility antigen

1983 • 84 citations

Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island.

1987 • 79 citations

Conversion of a PI-Anchored Protein to an Integral Membrane Protein by a Single Amino Acid Mutation

1988 • 70 citations

Organization of the human class I major histocompatibility complex genes

1987 • 65 citations

Class I-like HLA genes map telomeric to the HLA-A2 locus in human cells

1983 • 64 citations

Molecular Organization of the Class I Genes of Human Major Histocompatibility Complex

1985 • 62 citations

Structure, expression, and molecular mapping of a divergent member of the class I HLA gene family.

1987 • 58 citations

Isolation and nucleotide sequence of a cDNA clone encoding a novel HLA class I gene.

1988 • 57 citations

Sequences of Human Repetitive DNA, Non- -globin Genes, and Major Histocompatibility Locus Genes: III. The Major Histocompatibility Complex

1983 • 53 citations

Comparison of class I (H-2) gene sequences. Derivation of unique probes for members of this multigene family.

1983 • 52 citations

Transcripts of human HLA gene fragments lacking the 5'-terminal region in transfected mouse cells.

1984 • 48 citations

Organization and Expression of the MHC of the C57 Black/10 Mouse

1985 • 47 citations

Thymus-leukemia (TL) antigens of the mouse. Analysis of TL mRNA and TL cDNA TL+ and TL- strains.

1985 • 47 citations

The genomic organisation and nucleotide sequence of the HLA-SB(DP) alpha gene

1985 • 47 citations

Sequence of the mouse Q4 class I gene and characterization of the gene product

1988 • 44 citations

Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.

1985 • 41 citations

Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA.

1983 • 39 citations

CpG islands and HTF islands in the HLA class I region: investigation of the methylation status of class I genes leads to precise physical mapping of the HLA-B and -C genes

1988 • 36 citations

Multiple enhancer-like sequences in the HLA-B7 gene.

1989 • 36 citations

[55] HLA antigens in serum

1984 • 36 citations

Deletion mapping of HLA and chromosome 6p genes.

1985 • 35 citations

HLA Class I Genes: From Structure to Expression, Serology and Function

1985 • 31 citations

HLA-B locus polymorphism: studies with a specific hybridization probe.

1985 • 26 citations

A novel human major histocompatibility complex class I-type DNA sequence

1988 • 20 citations

Molecular biology of the mouse Q region

1987 • 15 citations

Transcripts of Tla genes

1987 • 10 citations

Cloning and Structure Analysis of Histocompatibility Class I and Class II Genes

1984 • 5 citations