The Biosynthesis of Collagen

The Structure Of Collagen And Gelatin

1962 • 391 citations

An autoradiographic and electron microscopic study of collagen synthesis in differentiating cartilage

1963 • 367 citations

The Structure of the Disaccharide Unit of the Renal Glomerular Basement Membrane

1967 • 333 citations

Cofactor and substrate requirements of collagen proline hydroxylase

1967 • 300 citations

WOUND HEALING AND COLLAGEN FORMATION

1965 • 298 citations

Synthesis and extrusion of collagen by freshly isolated cells from chick embryo tendon

1971 • 280 citations

SOME ASPECTS OF THE METABOLISM OF HYDROXYPROLINE, STUDIED WITH THE AID OF ISOTOPIC NITROGEN

1949 • 277 citations

The Nature of the Collagen Synthesized by Cultured Human Fibroblasts

1971 • 238 citations

Evidence for Procollagen, a Biosynthetic Precursor of Collagen

1971 • 193 citations

Collagen Proline Hydroxylase in Wound Healing, Granuloma Formation, Scurvy, and Growth

1967 • 185 citations

ENZYMATIC HYDROXYLATION OF PROLINE IN MICROSOMAL POLYPEPTIDE LEADING TO FORMATION OF COLLAGEN

1965 • 184 citations

Hydroxylation of Proline and the Intracellular Accumulation of a Polypeptide Precursor of Collagen

1966 • 180 citations

Conversion of Proline to Collagen Hydroxyproline in a Cell-free System from Chick Embryo

1963 • 180 citations

THE METABOLISM OF l(-)-PROLINE STUDIED WITH THE AID OF DEUTERIUM AND ISOTOPIC NITROGEN

1944 • 176 citations

ENZYMATIC HYDROXYLATION OF PROLINE AND LYSINE IN PROTOCOLLAGEN

1967 • 171 citations

Hydroxylation of Proline in Synthetic Polypeptides with Purified Protocollagen Hydroxylase

1967 • 167 citations

Purification and properties of collagen proline hydroxylase from newborn rat skin

1970 • 152 citations

Comparative Sequence Studies of Rat Skin and Tendon Collagen. I. Evidence for Incomplete Hydroxylation of Individual Prolyl Residues in the Normal Proteins^*

1967 • 149 citations

Further evidence for a transport form of collagen. Its extrusion and extracellular conversion to tropocollagen in embryonic tendon

1971 • 135 citations

Glycoprotein biosynthesis: The localization of polypeptidyl: N-acetylgalactosaminyl, collagen: Glucosyl, and glycoprotein: Galactosyl transferases in HeLa cell membrane fractions

1968 • 133 citations

SYNTHESIS OF HYDROXYPROLINE IN VITRO BY THE HYDROXYLATION OF PROLINE IN A PRECURSOR OF COLLAGEN

1965 • 130 citations

Hydroxylation of proline residues in collagen nascent chains

1970 • 129 citations

Studies on the Biosynthesis of the Hydroxylysine-linked Disaccharide Unit of Basement Membranes and Collagens

1971 • 127 citations

Decarboxylation of alpha-ketoglutarate coupled to collagen proline hydroxylase.

1968 • 127 citations

Influence of chelating agents on the biosynthesis of collagen

1965 • 119 citations

Incorporation of 18O from air into hydroxyproline by chick embryo

1962 • 113 citations

The Formation of Triple‐Helical Collagen Molecules from α1 or α2 Polypeptide Chains

1969 • 108 citations

Purification and partial characterization of the enzyme for the hydroxylation of proline in protocollagen

1967 • 106 citations

Isolation and partial characterization of highly purified protocollagen proline hydroxylase

1970 • 93 citations

Cofactor requirements for the enzymatic hydroxylation of lysine in a polypeptide precursor of collagen

1967 • 93 citations

Studies on the Biosynthesis of the Hydroxylysine-linked Disaccharide Unit of Basement Membranes and Collagens

1971 • 92 citations

Attachment of carbohydrate to collagen. Isolation, purification and properties of the glucosyl transferase

1968 • 92 citations

Proposed Mechanism for the Biological Assembly of Collagen Triple Helix

1971 • 85 citations

Collagen synthesis on polyribosomes of cultured mammalian fibroblasts

1967 • 84 citations

THE CONVERSION OF LYSINE TO HYDROXYLYSINE AND ITS RELATION TO THE BIOSYNTHESIS OF COLLAGEN IN SEVERAL TISSUES OF THE RAT

1957 • 79 citations

Oxygen-18 studies on the conversion of proline to collagen hydroxyproline

1963 • 79 citations

Dissociation of the synthesis of sulphated mucopolysaccharides and the synthesis of collagen in embryonic cartilage

1966 • 77 citations

THE SOURCE AND STATE OF THE HYDROXYLYSINE OF COLLAGEN

1955 • 75 citations

Synthetic polypeptides as substrates and inhibitors of collagen proline hydroxylase

1968 • 75 citations

INTRACELLULAR ACCUMULATION OF PROTOCOLLAGEN AND EXTRUSION OF COLLAGEN BY EMBRYONIC CARTILAGE CELLS

1968 • 75 citations

Studies on the Biosynthesis of the Hydroxylysine-linked Disaccharide Unit of Basement Membranes and Collagens

1971 • 75 citations

Synthesis of Collagen on Polyribosomes

1964 • 74 citations

H³‐proline incorporation into cartilage: Electron microscope autoradiographic observations

1968 • 74 citations

Glycoprotein biosynthesis: The biosynthesis of the hydroxylysine-galactose linkage in collagen

1968 • 68 citations

Partial characterization of protocollagen from embryonic cartilage

1967 • 67 citations

Collagen polysomes: Site of hydroxylation of proline residues

1971 • 66 citations

The Source and State of the Hydroxylysine of Collagen

1959 • 66 citations

Kinetic patterns of protocollagen hydroxylase and further studies on the polypeptide substrate

1968 • 62 citations

Formation of Enzyme-Substrate Complexes with Protocollagen Proline Hydroxylase and Large Polypeptide Substrates

1969 • 59 citations

Biosynthesis of the α Chains of Collagen Studied by Pulse-labeling in Culture

1970 • 56 citations

Hydroxylation of lysine in a polypeptide precursor of collagen

1966 • 52 citations

Partial Hydroxylation of Certain Lysines In Collagen

1968 • 51 citations

Hydroxylation of proline in particulate fractions from cartilage

1965 • 46 citations

The sulfhydryl nature of collagen proline hydroxylase

1969 • 44 citations

The Incomplete Hydroxylation of Individual Prolyl Residues in Collagen

1967 • 43 citations

α-Ketoglutarate and hydroxylation of γ-butyrobetaine

1968 • 41 citations

BIOSYNTHESIS OF COLLAGEN

1967 • 41 citations

Oligopeptides with the Sequences Ala-Pro-Gly and Gly-Pro-Gly as Substrates or Inhibitors for Protocollagen Proline Hydroxylase

1969 • 40 citations

Effect of Polymer Size on the Inhibition of Protocollagen Proline Hydroxylase by Polyproline II

1969 • 39 citations

The size of the polypeptide precursor of collagen hydroxyproline.

1966 • 39 citations

Hydroxylation of proline and lysine in protocollagen involves two separate enzymatic sites

1969 • 38 citations

The polyribosomal synthesis of collagen

1967 • 36 citations

Inhibition of collagen hydroxylysine formation by chelating agents

1967 • 24 citations

The absence of iron and certain coenzymes in highly purified protocollagen proline hydroxylase

1971 • 19 citations

Electron Microscopy of Protocollagen Proline Hydroxylase from Chick Embryos

1970 • 18 citations

Hydroxyprolyl-soluble ribonucleic acid and the biosynthesis of collagen

1966 • 15 citations

Site of proline hydroxylation during collagen synthesis in mouse fibroblasts

1970 • 12 citations

The Intracellular Biosynthesis of Collagen

1969 • 11 citations

In vitro Incorporation and Hydroxylation of Lysine-2-C14 In Rat Biopsy-Connective Tissue.

1958 • 9 citations