Thyrotoxicosis as a Disease of Mitochondria

OXIDATIVE PHOSPHORYLATIONS: RÔLE OF INORGANIC PHOSPHATE AND ACCEPTOR SYSTEMS IN CONTROL OF METABOLIC RATES

1952 • 744 citations

UPTAKE OF RADIOACTIVE ALANINE IN VITRO INTO THE PROTEINS OF RAT LIVER FRACTIONS

1952 • 691 citations

REVERSIBLE INHIBITION OF THE COUPLING BETWEEN PHOSPHORYLATION AND OXIDATION

1948 • 656 citations

THE EFFECT OF THYROXINE AND OTHER SUBSTANCES ON THE SWELLING OF ISOLATED RAT LIVER MITOCHONDRIA

1956 • 278 citations

INACTIVATION OF OXIDATIVE AND PHOSPHORYLATIVE SYSTEMS IN MITOCHONDRIA BY PREINCUBATION WITH PHOSPHATE AND OTHER IONS

1955 • 277 citations

OXIDATIVE PHOSPHORYLATION BY AN ENZYME COMPLEX FROM EXTRACTS OF MITOCHONDRIA

1956 • 260 citations

PLASMA NONESTERIFIED FATTY ACIDS IN HYPERTHYROID STATES

1959 • 210 citations

OXIDATIVE PHOSPHORYLATION BY AN ENZYME COMPLEX FROM EXTRACTS OF MITOCHONDRIA

1957 • 192 citations

The mode of action of thyroxin

1951 • 178 citations

THE UNCOUPLING OF RESPIRATION AND PHOSPHORYLATION BY THYROID HORMONES

1954 • 176 citations

OXIDATIVE PHOSPHORYLATION BY AN ENZYME COMPLEX FROM EXTRACTS OF MITOCHONDRIA

1957 • 163 citations

Thyroxine Stimulation of Amino Acid Incorporation into Protein

1961 • 160 citations

PHOSPHORYLATION COUPLED TO OXIDATION IN BACTERIAL EXTRACTS

1956 • 153 citations

Oxidative Phosphorylation

1958 • 152 citations

The Swelling of Rat Liver Mitochondria by Thyroxine and its Reversal

1959 • 148 citations

Mechanism of Action of the Thyroid Hormone

1951 • 144 citations

Movements of water and ions in mitochondria

1956 • 141 citations

METABOLIC EFFECTS OF THYROID HORMONES IN VITRO

1953 • 139 citations

Clinical and Metabolic Studies in Thyroid Disease--I

1960 • 138 citations

Uncoupling of oxidative phosphorylation in mitochondria from fatty livers

1954 • 137 citations

ESTERIFICATION OF INORGANIC PHOSPHATE COUPLED TO ELECTRON TRANSPORT BETWEEN DIHYDRODIPHOSPHOPYRIDINE NUCLEOTIDE AND OXYGEN. II

1949 • 132 citations

THE EFFECT OF THYROXINE AND RELATED COMPOUNDS ON OXIDATIVE PHOSPHORYLATION

1956 • 114 citations

The action of thyroxine on mitochondria and oxidative phosphorylation

1955 • 113 citations

The Mitochondrion and Biochemical Machines

1961 • 106 citations

Effect of Insulin on the Metabolism of Adipose Tissue from Hyperthyroid Rats

1960 • 105 citations

OXIDATIVE PHOSPHORYLATION BY AN ENZYME COMPLEX FROM EXTRACTS OF MITOCHONDRIA

1956 • 104 citations

THE MECHANISM RESPONSIBLE FOR THE ALTERED BLOOD CHOLESTEROL CONTENT IN DERANGED THYROID STATES*†

1952 • 102 citations

INTRAMITOCHONDRIAL REGULATION OF OXIDATIVE RATE

1953 • 101 citations

A STUDY OF ACETATE METABOLISM AND FATTY ACID SYNTHESIS IN LIVER SLICES OF HYPERTHYROID RATS

1953 • 101 citations

EFFICIENCY OF PHOSPHORYLATION IN SELECTED OXIDATIONS BY MITOCHONDRIA FROM NORMAL AND THYROTOXIC RAT LIVERS

1955 • 101 citations

THE EFFECT OF MAGNESIUM DEFICIENCY ON OXIDATIVE PHOSPHORYLATION

1957 • 98 citations

METABOLIC EFFECTS OF THYROXINE IN VITRO

1951 • 92 citations

Effect of single and chronic thyroxine injection on fatty acid and cholesterol synthesis in mice

1959 • 91 citations

A STUDY OF THE RATE OF PROTEIN SYNTHESIS BEFORE AND DURING THE ADMINISTRATION OF L-TRIIODOTHYRONINE TO PATIENTS WITH MYXEDEMA AND HEALTHY VOLUNTEERS USING N-15 GLYCINE 1

1956 • 79 citations

PHOSPHORYLATION COUPLED TO THE OXIDATION OF ASCORBIC ACID BY ISOLATED MITOCHONDRIA

1954 • 79 citations

Influence of Thyroid Activity on Excretion of Bile Acids and Cholesterol in the Rat.

1957 • 78 citations

CYTOCHROME c METABOLISM AND LIVER REGENERATION. INFLUENCE OF THYROID GLAND AND THYROXINE

1950 • 73 citations

Effect of Thyroxine on the Swelling of Mitochondria isolated from Various Tissues of the Rat

1956 • 73 citations

Influence of the thyroid on the synthesis of cholesterol by liver and skin in vitro

1958 • 72 citations

ENDOCRINE REGULATION OF AMINO ACID LEVELS IN BLOOD AND TISSUES

1947 • 69 citations

THE EFFECT OF THYROXINE ON MAGNESIUM REQUIREMENT

1957 • 69 citations

The uncoupling of oxidative phosphorylation in rat-liver mitochondria by thyroxine, triiodothyronine and related substances

1955 • 69 citations

OXIDATIVE PHOSPHORYLATION BY AN ENZYME COMPLEX FROM EXTRACTS OF MITOCHONDRIA

1956 • 62 citations

The effects of some inhibitors of oxidative phosphorylation on the morphology and enzymic activities of mitochondria

1956 • 61 citations

Rates of acetate turnover and lipid synthesis in normal, hypothyroid and hyperthyroid rats

1960 • 57 citations

THE EFFECT OF THYROID ACTIVITY ON CERTAIN ANABOLIC PROCESSES STUDIED WITH THE AID OF DEUTERIUM

1949 • 57 citations

Effects of thyroid hormones in vitro on tissue respiration, oxidative phosphorylation and the swelling of mitochondria

1956 • 56 citations

THYROXINE AND THE SWELLING AND CONTRACTION CYCLE IN MITOCHONDRIA*

1960 • 53 citations

IMMEDIATE EFFECTS OF THYROXINE ANALOGUES ON BIOLOGICAL OXIDATIONS IN VITRO

1955 • 50 citations

THE EFFECT OF A SINGLE INJECTION OF THYROXIN ON CARBOHYDRATES, PROTEIN AND GROWTH IN THE RAT LIVER¹

1939 • 49 citations

Effects of Thyroxin on Amino Acid Incorporation into Protein

1959 • 49 citations

PHOSPHORYLATIONS ASSOCIATED WITH THE OXIDATION OF EXTERNAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE BY RAT LIVER MITOCHONDRIA

1957 • 47 citations

Uptake and binding of thyroxine and triiodothyronine by rat diaphragm in vitro

1961 • 47 citations

THE INFLUENCE OF THYROID ACTIVITY ON THE LIVER AND PLASMA LIPIDES OF CHOLINE- AND CYSTINE-DEFICIENT RATS

1948 • 45 citations

The effect of thyroxine on the swelling of mitochondria isolated from normal and neoplastic livers

1957 • 44 citations

RATE OF CHOLESTEROL SYNTHESIS IN HYPO- AND HYPERTHYROID RATS

1952 • 43 citations

THE EFFECT OF THYROXINE ON THE COENZYME A CONTENT OF SOME TISSUES

1954 • 39 citations

THE METABOLIC EFFECTS OF THE ACETIC AND PROPIONIC ACID ANALOGS OF THYROXINE AND TRIIODOTHYRONINE*

1960 • 37 citations

THE SOLUBILITY OF MALACHITE

1957 • 37 citations

A DISSOCIATION OF THYROID HORMONAL EFFECTS BY STRUCTURAL ALTERATIONS OF THE THYROXINE MOLECULE

1959 • 35 citations

INFLUENCE OF THYROXINE ON PROTEIN METABOLISM

1949 • 32 citations

THE RATES OF SYNTHESIS AND THE TRANSPORT OF PLASMA FATTY ACID FRACTIONS IN MAN 1

1955 • 32 citations

Effects of thyroxine on the synthesis of cholesterol and fatty acids by cell‐free fractions of rat liver

1960 • 31 citations

Effects of Thyroxine, Thyroidectomy and Lowered Environmental Temperature on Incorporation of Deuterium into Cholesterol.

1953 • 29 citations

Thyroxine-mediated release of diphosphopyridine nucleotide from mitochondrial dehydrogenases

1958 • 28 citations

MAGNESIUM ANTAGONISM OF THE UNCOUPLING OF OXIDATIVE PHOSPHORYLATION BY IODO-THYRONINES

1955 • 27 citations

Some actions of thyroxine on oxidative phosphorylation

1960 • 27 citations

The uncoupling of oxidative phosphorylation by thyroxine and triiodothyronine in ultrasonic extracts of liver mitochondria

1958 • 26 citations

Thyroxine-enhanced oxidative phosphorylation of rat-liver mitochondria

1960 • 25 citations

ACETYLATION STUDIES IN HUMAN SUBJECTS WITH METABOLIC DISORDERS 1

1950 • 22 citations

METABOLIC EFFECTS OF THYROXINE ANALOGUES IN HUMAN MYXEDEMA*

1960 • 19 citations

THE INFLUENCE OF THYROXINE AND RELATED COMPOUNDS ON OXIDATIVE RATE AND EFFICIENCY OF PHOSPHORYLATION IN LIVER MITOCHONDRIA AND SUBMITOCHONDRIAL PARTICLES*

1960 • 19 citations

Some effects of thyroxin on oxidative phosphorylation in submitochondrial particles and intact mitochondria

1958 • 19 citations

IN VITROACTION OF THYROXINE ANALOGS ON SUCCINATE AND MALATE OXIDATION¹

1957 • 18 citations

The Thyroid Gland

1960 • 17 citations

The Effect of Thyroxine on Mitochondrial Stability.

1956 • 17 citations

The action of thyroxine and triiodothyronine on human cells growing in tissue culture

1959 • 17 citations

The effect of analogues of thyroxine and 2,4-dinitrophenol on the swelling of mitochondria

1959 • 16 citations

LIVER ENZYME PATTERN IN THYROTOXICOSIS

1959 • 16 citations

THE EFFECTS OF THYROXINE AND CERTAIN METAL IONS UPON OXIDATION AND PHOSPHORYLATIONIN VITRO1

1957 • 13 citations

Stimulating effect of thyroxine in contraction of rat liver mitochondria

1960 • 13 citations

Diseases of the Thyroid Gland

1952 • 12 citations

Metabolic effects and therapeutic applications of triiodothyropropionic acid

1961 • 11 citations

Acetylation of Sulfanilamide as Influenced by the Thyroid.

1946 • 10 citations

The Effect of Thyroxine on Mitochondrial Oxidation and Swelling

1960 • 10 citations

The in Vitro Effects of Sodium Azide on Tissues of Normal and Thyroid-Fed Rats

1952 • 10 citations

Reversal by Acetylcholine of the Inhibition by Thyroxine of Oxidative Phosphorylation in Guinea-pig Heart Sarcosomes

1959 • 8 citations

EFFECTS OF THYROXINE AND SOME RELATED COMPOUNDS ON BACTERIAL OXIDATIONS

1955 • 8 citations

THE EFFECT OF DESICCATED THYROID ON THE HYPERLIPOPROTEINEMIA OF XANTHOMA TENDINOSUM

1960 • 8 citations

THE MECHANISM OF ACTION OF THYROID HORMONES

1958 • 7 citations

The effect of thyroxine on the oxidative phosphorylation of tumour mitochondria

1957 • 7 citations

Effect of the thyroid on butyrate oxidation in the rat heart

1960 • 7 citations

Influence of L-3′,5,3-Triiodothyronine on the Oxidative Phosphorylation of Tumour Mitochondria

1959 • 6 citations

Uncoupling of phosphorylation by l-thyroxine in a subcellular particulate fraction of yeast

1959 • 6 citations

THYROXINE ANALOGUES AND CHOLESTEROL METABOLISM: THE PREVENTION AND REVERSAL OF ELEVATED LIVER CHOLESTEROL AND LIPID CONCENTRATIONS IN THE CHOLESTEROL FED RAT BY DIETARY3,5 DIIODOTHYROACETIC ACID¹

1961 • 5 citations

Stimulation of bacterial oxidations by thyroxine in vitro

1954 • 4 citations

Effect of physiological levels of thyroxine on phosphorylation in rat-liver mitochondria

1959 • 4 citations

Dietary magnesium and oxygen consumption

1959 • 3 citations