Differential transformation of mammary epithelial cells by Wnt genes.

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1988 • 745 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.

1990 • 327 citations

Demonstration of an Adhering-Junction Molecule (Plakoglobin) in the Autoantigens of Pemphigus Foliaceus and Pemphigus Vulgaris

1989 • 280 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

Overlapping Expression of Xwnt-3A and Xwnt-1 in Neural Tissue of Xenopus laevis Embryos

1993 • 202 citations

The development of wingless, a homeotic mutation of Drosophila

1977 • 185 citations

Epidermal growth factor requirement for development of cultured mammary gland

1980 • 165 citations

Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland.

1992 • 156 citations

Local effects of EGF, α‐TGF, and EGF‐like growth factors on lobuloalveolar development of the mouse mammary gland in vivo

1987 • 147 citations

Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis

1987 • 145 citations

Epidermal Growth Factor Stimulates Cell Proliferation and Inhibits Functional Differentiation of Mouse Mammary Epithelial Cells in Culture*

1983 • 126 citations

Desmoglein shows extensive homology to the cadherin family of cell adhesion molecules

1990 • 120 citations

Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line.

1992 • 109 citations

Insulin is essential for accumulation of casein mRNA in mouse mammary epithelial cells.

1981 • 97 citations

Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice

1991 • 85 citations

Localization and Quantification of Wnt-2 Gene Expression in Mouse Mammary Development

1993 • 80 citations

The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death

1989 • 77 citations

Cadherins: A Molecular Family Important In Selective Cell-Cell Adhesion

1990 • 76 citations

Murine mammary tumor virus (MuMTV) infection of an epithelial cell line established from C57BL/6 mouse mammary glands

1978 • 68 citations

Inhibition of mouse mammary ductal morphogenesis and down-regulation of the EGF receptor by epidermal growth factor

1990 • 67 citations

CHANGES IN INSULIN RESPONSIVENESS DURING DEVELOPMENT OF MAMMARY EPITHELIUM

1974 • 52 citations

The Wnt family of developmental regulators

1992 • 37 citations

Changes in Scatchard Plots for Insulin Binding to Mammary Epithelial Cells from Cycling, Pregnant, and Lactating Mice*

1982 • 36 citations

Growth Control and Differentiation in Mammary Epithelial Cells

1989 • 15 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1992 • 14 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of vegetal dorsalizing center

1992 • 9 citations

Secreted int-1 Protein Is Associated with the Cell Surface

1990 • 8 citations

High-Risk Breast Cancer: Definition of the Risk

1989 • 2 citations