High levels of human glucocerebrosidase activity in macrophages of long- term reconstituted mice after retroviral infection of hematopoietic stem cells

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges.

1988 • 908 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Therapeutic response to intravenous infusions of glucocerebrosidase in a patient with Gaucher disease.

1990 • 374 citations

BENEFICIAL EFFECT OF PRE-TRANSPLANT SPLENECTOMY ON DISPLACEMENT BONE MARROW TRANSPLANTATION FOR GAUCHER'S SYNDROME

1987 • 98 citations

Correction of glucocerebrosidase deficiency after retroviral-mediated gene transfer into hematopoietic progenitor cells from patients with Gaucher disease.

1990 • 93 citations

Expression of Introduced Genetic Sequences in Hematopoietic Cells Following Retroviral-Mediated Gene Transfer

1990 • 92 citations

Monoclonal Antibodies against Human β‐Glucocerebrosidase

1983 • 51 citations

Toward Gene Therapy for Gaucher Disease

1991 • 50 citations

Production of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.

1989 • 41 citations

Expression of human glucocerebrosidase following retroviral vector-mediated transduction of murine hematopoietic stem cells.

1991 • 30 citations

Expression of Human Glucocerebrosidase in Long-Term Reconstituted Mice Following Retroviral-Mediated Gene Transfer into Hematopoietic Stem Cells

1990 • 26 citations

Molecular cloning and nucleotide sequence of human glucocerebrosidase cDNA

1986 • 19 citations

Enzyme replacement therapy for Gaucher disease

1991 • 18 citations

Treatment of genetic defects in hematopoietic cell function by gene transfer

1991 • 12 citations

Retroviral gene transfer of human adenosine deaminase in murine hematopoietic cells: effect of selectable marker sequences on long-term expression

1991 • 7 citations

Expression of human glucocerebrosidase in murine long-term bone marrow cultures after retroviral vector-mediated transfer

1990 • 2 citations