Receptor Mapping

Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex.

1978 • 229 citations

Three-Dimensional Pharmacophoric Pattern Searching

1977 • 149 citations

Three-Dimensional Molecular Modeling and Drug Design

1980 • 124 citations

Chapter 29 Pharmacophoric Pattern Searching and Receptor Mapping

1979 • 53 citations

Neuroleptic agents of the benzocycloheptapyridoisoquinoline series. 1. Syntheses and stereochemical and structural requirements for activity of butaclamol and related compounds

1975 • 47 citations

Synthesis and biological activity of (6aS)-10,11-dihydroxyaporphine, the optical antipode of apomorphine

1973 • 46 citations

Mapping the dopamine receptor. 2. Features derived from modifications in the rings A/B region of the neuroleptic butaclamol

1979 • 36 citations

Behavioral studies on the enantiomers of butaclamol demonstrating absolute optical specificity for neuroleptic activity

1976 • 24 citations

Crystallographic studies on neuroleptics of the benzocycloheptapyridoisoquinoline series. The crystal structure of butaclamol hydrobromide and the absolute configuration and crystal structure of dexclamol hydrobromide

1976 • 19 citations

(+)-Isobutaclamol: a crystallographic, pharmacological, and biochemical study

1979 • 10 citations

Neuroleptics related to butaclamol. Synthesis and some psychopharmacological effects of a series of 3-aryl analogues

1978 • 8 citations

Crystal structure and absolute configuration of the neuroleptic agent (+)-isobutaclamol hydrobromide

1979 • 7 citations