The management of heparin‐induced thrombocytopenia

Temporal Aspects of Heparin-Induced Thrombocytopenia

2001 • 946 citations

Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis

2005 • 838 citations

Heparin-Induced Thrombocytopenia: Recognition, Treatment, and Prevention

2004 • 826 citations

Impact of the patient population on the risk for heparin-induced thrombocytopenia

2000 • 650 citations

Safety of Low-Molecular-Weight Heparin in Pregnancy: A Systematic Review

1999 • 554 citations

Heparin‐induced thrombocytopenia: pathogenesis and management

2003 • 544 citations

Heparin-induced thrombocytopenia and cardiac surgery

2003 • 543 citations

Recombinant Hirudin (Lepirudin) Provides Safe and Effective Anticoagulation in Patients With Heparin-Induced Thrombocytopenia

1999 • 502 citations

The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia

1997 • 478 citations

Lepirudin (Recombinant Hirudin) for Parenteral Anticoagulation in Patients With Heparin-Induced Thrombocytopenia

1999 • 352 citations

An Improved Definition of Immune Heparin-Induced Thrombocytopenia in Postoperative Orthopedic Patients

2003 • 323 citations

Laboratory diagnosis of heparin‐associated thrombocytopenia and comparison of platelet aggregation test, heparin‐induced platelet activation test, and platelet factor 4/heparin enzyme‐linked immunosorbent assay

1994 • 304 citations

The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin: a prospective cohort study

2003 • 281 citations

Anti–platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin

2005 • 275 citations

Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia

2004 • 275 citations

Venous thromboembolism during pregnancy: a retrospective study of enoxaparin safety in 624 pregnancies

2001 • 272 citations

Laboratory testing for the antibodies that cause heparin-induced thrombocytopenia: How much class do we need?

2005 • 262 citations

The Clinical Usefulness of the Platelet Aggregation Test for the Diagnosis of Heparin-Induced Thrombocytopenia

1993 • 261 citations

Thrombosis and ELISA optical density values in hospitalized patients with heparin‐induced thrombocytopenia

2004 • 242 citations

Laboratory diagnosis of immune heparin-induced thrombocytopenia.

2003 • 239 citations

Anaphylactic and Anaphylactoid Reactions Associated With Lepirudin in Patients With Heparin-Induced Thrombocytopenia

2003 • 226 citations

Heparin-induced thrombocytopenia

2003 • 221 citations

Antihirudin antibodies in patients with heparin-induced thrombocytopenia treated with lepirudin: incidence, effects on aPTT, and clinical relevance

2000 • 218 citations

Treatment of Heparin-Induced Thrombocytopenia

2004 • 214 citations

The incidence of heparin-induced thrombocytopenia in medical patients treated with low-molecular-weight heparin: a prospective cohort study

2005 • 213 citations

A Comparison of Danaparoid and Lepirudin in Heparin-induced Thrombocytopenia

2001 • 195 citations

Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.

1992 • 190 citations

Heparin‐induced skin lesions

1996 • 182 citations

First Workshop for Detection of Heparin-induced Antibodies: Validation of the Heparin-induced Platelet-activation Test (HIPA) in Comparison with a PF4/Heparin ELISA

1999 • 163 citations

Prospective Randomised Open-label Comparison of Danaparoid with Dextran 70 in the Treatment of Heparin-induced Thrombocytopaenia with Thrombosis

2001 • 162 citations

New Approaches to the Diagnosis of Heparin-Induced Thrombocytopenia

2005 • 159 citations

The epitope specificity of heparin‐induced thrombocytopenia

1996 • 156 citations

Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies

2004 • 145 citations

Bivalent direct thrombin inhibitors: hirudin and bivalirudin

2004 • 139 citations

Incidence and clinical relevance of heparin‐induced antibodies in patients with deep vein thrombosis treated with unfractionated or low‐molecular‐weight heparin

2002 • 134 citations

Quantitative Determination of Hirudin in Blood and Body Fluids

1996 • 128 citations

The Pathophysiology of Heparin-Induced Thrombocytopenia

2005 • 110 citations

Antenatal use of enoxaparin for prevention and treatment of thromboembolism in pregnancy

2000 • 104 citations

New Anticoagulants for the Cardiovascular Patient

1995 • 97 citations

Anticoagulation during Cardiopulmonary Bypass in Patients with Heparin-induced Thrombocytopenia Type II and Renal Impairment Using Heparin and the Platelet Glycoprotein IIb–IIIa Antagonist Tirofiban

2001 • 95 citations

Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin‐induced thrombocytopenia

2002 • 90 citations

Efficacy and Safety of Danaparoid Sodium (ORG 10172) in Critically Ill Patients With Heparin-Associated Thrombocytopenia

1999 • 86 citations

Cross-reactivity study of low molecular weight heparins and heparinoid in heparin-induced thrombocytopenia

1996 • 77 citations

Cardiac surgery with cardiopulmonary bypass in patients with type II heparin-induced thrombocytopenia

2001 • 65 citations

Bivalirudin: a review

2005 • 65 citations

Patients with a History of Type II Heparin-Induced Thrombocytopenia with Thrombosis Requiring Cardiac Surgery with Cardiopulmonary Bypass: A Prospective Observational Case Series

2003 • 63 citations

Heparin‐induced thrombocytopenia: cross‐reactivity between standard heparin, low molecular weight heparin, dalteparin (Fragmin) and heparinoid, danaparoid (Orgaran)

1995 • 45 citations

Heparin-Induced Thrombocytopenia

2003 • 43 citations

Heparin‐induced thrombocytopenia and thrombosis syndrome: in vivo cross‐reactivity with danaparoid and successful treatment with r‐Hirudin

2001 • 40 citations

Management of urgent high-risk cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II and coexisting disorders of renal function: Use of heparin and epoprostenol combined with on-line monitoring of platelet function

2000 • 35 citations

Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome

1996 • 34 citations

Platelet aggregation in response to four low molecular weight heparins and the heparinoid ORG 10172 in patients with heparin‐induced thrombocytopenia

1994 • 34 citations

Recombinant hirudin as an alternative for anticoagulation during cardiopulmonary bypass in patients with heparin-induced thrombocytopenia type II: A 1-year experience in 57 patients

2000 • 31 citations

Heparin-induced thrombocytopenia in neurologic patients treated with low-molecular-weight heparin

2005 • 26 citations

On the Prophylactic and Therapeutic Use of Danaparoid Sodium (Orgaran®) in Patients With Heparin-Induced Thrombocytopenia

2003 • 15 citations

Acute heparin-induced thrombocytopenia type II during cardiopulmonary bypass

2000 • 5 citations