The Role of Mitochondrial Hexokinase Binding in the Abnormal Energy Metabolism of Tumor Cell Lines

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Methods of Enzymatic Analysis

1975 • 20,446 citations

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.

1979 • 1,228 citations

Tumor Mitochondria and the Bioenergetics of Cancer Cells

2015 • 720 citations

Multiple Hexokinases of Rat Tissues

1966 • 483 citations

THE ASSOCIATION OF HEXOKINASE WITH PARTICULATE FRACTIONS OF BRAIN AND OTHER TISSUE HOMOGENATES

1953 • 460 citations

A candidate for the permeability pathway of the outer mitochondrial membrane

1979 • 459 citations

Mitochondrial Hexokinase

1967 • 391 citations

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

1977 • 378 citations

Energy metabolism of tumor cells. Requirement for a form of hexokinase with a propensity for mitochondrial binding.

1981 • 307 citations

Glycolysis, glutaminolysis and cell proliferation

1982 • 305 citations

The glycolysis and respiration of tumors

1961 • 285 citations

Evidence for identity between the hexokinase-binding protein and the mitochondrial porin in the outer membrane of rat liver mitochondria

1982 • 254 citations

THE CARBOHYDRATE METABOLISM OF TUMORS

1925 • 234 citations

Pore protein and the hexokinase‐binding protein from the outer membrane of rat liver mitochondria are identical

1982 • 222 citations

Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC

1986 • 210 citations

Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.

1980 • 186 citations

Purification of a hexokinase-binding protein from the outer mitochondrial membrane.

1979 • 161 citations

Purification and properties of rat brain hexokinase

1972 • 151 citations

Intracellular localization and properties of particulate hexokinase in the Novikoff ascites tumor. Evidence for an outer mitochondrial membrane location.

1983 • 145 citations

The functional compartmentation of mitochondrial hexokinase

1974 • 120 citations

Issues in the in vivo measurement of glucose metabolism of human central nervous system tumors

1984 • 112 citations

Alterations in Glucose Metabolism in Chick-Embryo Cells Transformed by Rous Sarcoma Virus: Intracellular Levels of Glycolytic Intermediates

1974 • 95 citations

The purification in high yield and characterization of rat hepatic glucokinase

1976 • 94 citations

Ascites Tumor Mitochondrial Hexokinase II

1968 • 81 citations

Purification and properties of rat skeletal muscle hexokinase

1976 • 76 citations

Alterations in glucose metabolism in chick embryo cells transformed by Rous sarcoma virus

1974 • 71 citations

Mitochondrial hexokinase of rat hepatoma cells in culture: solubilization and kinetic properties

1980 • 66 citations

On the impermeability of the outer mitochondrial membrane to cytochromec

1972 • 58 citations

A possible interrelationship between binding of hexokinase and the site of ATP formation in Krebs ascites cells

1969 • 32 citations

Phase II Evaluation of Lonidamine in Patients with Advanced Malignancy

1984 • 24 citations

Correlation of Experimental and Clinical Studies of Metabolism by PET Scanning

2015 • 20 citations

Binding potential of brain hexokinase to mitochondria membrane

1979 • 15 citations

Enhancement in the activities of mouse epidermal glucose-6-phosphate dehydrogenase, hexokinase, phosphofructokinase, and pyruvate kinase by 12-O-tetradecanoyl-phorbol-13-acetate

1985 • 12 citations

Studies on particle-bound hexokinase in rat ascites hepatoma cells

1971 • 10 citations

The effect of gossypol and lonidamine on electron transport in ehrlich ascites tumor mitochondria

1984 • 8 citations

Effect of urethane, dimethylnitrosamine, paraquat, and butylated hydroxytoluene on the activities of glycolytic key enzymes in mouse lung

1981 • 6 citations