Patient-controlled epidural analgesia with morphine or morphine plus ketamine for post-operative pain relief

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain

1985 • 1,294 citations

Intrathecal and Epidural Administration of Opioids

1984 • 1,198 citations

Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid

1991 • 448 citations

Itching after epidural and spinal opiates

1988 • 400 citations

Epidural Narcotic and Patient-controlled Analgesia for Post-cesarean Section Pain Relief

1988 • 223 citations

Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain

1996 • 205 citations

The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn

1992 • 200 citations

The effects of methionine- and leucine-enkephalin on spinal neurones of the cat

1979 • 184 citations

Is Ketamine or Its Preservative Responsible for Neurotoxicity in the Rabbit?

1993 • 152 citations

Oral administration of dextromethorphan prevents the development of morphine tolerance and dependence in rats

1996 • 148 citations

The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests

1994 • 135 citations

The pharmacology of pain signalling

1993 • 122 citations

Epidural Ketamine for Control of Postoperative Pain

1985 • 121 citations

Adding Ketamine in a Multimodal Patient-Controlled Epidural Regimen Reduces Postoperative Pain and Analgesic Consumption

1998 • 87 citations

The clinically tested N-methyl-d-aspartate receptor antagonist memantine blocks and reverses thermal hyperalgesia in a rat model of painful mononeuropathy

1995 • 78 citations

Spinal opiates: a review of their effect on spinal function with emphasis on pain processing

1987 • 74 citations

N‐methyl‐<scp>d</scp>‐aspartate receptor antagonists potentiate morphine's antinociceptive effect in the rat

1996 • 73 citations

Epidural ketamine for postoperative analgesia

1986 • 65 citations

Epidural Ketamine for Postoperative Pain Relief after Gynecologic Operations

1987 • 55 citations

Modulation of NMDA-induced currents by μ-opioid receptor agonist DAGO in acutely isolated rat spinal dorsal horn neurons

1991 • 44 citations

Effects of Ketamine on Low Intensity Tactile Sensory Input Are Not Dependent upon a Spinal Site of Action

1986 • 40 citations

A double‐blind comparison of epidural ketamine and diamorphine for postoperative analgesia

1989 • 36 citations

Evidence of a role for N-methyl-D-aspartate (NMDA) receptors in the facilitation of tail withdrawal after spinal transection

1994 • 30 citations