Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells.

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

1977 • 1,972 citations

A rapid in vitro assay for quantitating the invasive potential of tumor cells.

1987 • 1,787 citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 • 1,241 citations

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

1981 • 1,048 citations

The Biology of Cancer Invasion and Metastasis

1978 • 819 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Plasminogen activator in early embryogenesis: Enzyme production by trophoblast and parietal endoderm

1976 • 590 citations

Accurate Identification of Experimental Pulmonary Metastases2

1966 • 418 citations

Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus

1980 • 387 citations

Cancer Metastasis: Experimental Approaches, Theoretical Concepts, and Impacts for Treatment Strategies

1985 • 301 citations

NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.

1985 • 240 citations

The Complete Amino Acid Sequence of Low Molecular Mass Urokinase from Human Urine

1982 • 230 citations

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells.

1988 • 223 citations

Cathepsin B activity in B16 melanoma cells: a possible marker for metastatic potential.

1982 • 200 citations

The primary structure of high molecular mass urokinase from human urine

1982 • 191 citations

ACTIVATION OF PLASMINOGEN: A GENERAL MECHANISM FOR PRODUCING LOCALIZED EXTRACELLULAR PROTEOLYSIS

1978 • 176 citations

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma.

1984 • 173 citations

Tumorigenic and metastatic properties of "normal" and ras-transfected NIH/3T3 cells.

1985 • 159 citations

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas.

1987 • 136 citations

Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes.

1986 • 119 citations

Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors.

1983 • 116 citations

Synthesis of hepatitis B surface antigen in mammalian cells: expression of the entire gene and the coding region

1983 • 113 citations

Expression of the metastatic phenotype in cells transfected with human metastatic tumor DNA.

1985 • 109 citations

The Role of Hemostasis and Fibrinolysis in the Metastatic Spread of Cancer

1984 • 105 citations

Plasminogen activator in the rodent brain

1981 • 105 citations

Involvement of plasminogen activator production with tumor metastasis in a rat model.

1984 • 66 citations

Multiple forms of plasminogen activator in human breast tumors.

1985 • 56 citations

Chemical and Enzymatic Synthesis of Gene Fragments A Laboratory Manual

1984 • 47 citations

Sensitive autoradiographic quantification of electrophoretically separated proteases

1981 • 37 citations

Correlation of the production of plasminogen activator with tumor metastasis in B16 mouse melanoma cell lines

1980 • 36 citations

Influence of Plasma Fibronectin on Collagen Cleavage by Collagenase

1983 • 19 citations

Proteinases and proteinase inhibition by cytotoxic and antimetastatic drugs in transplantable solid metastasizing tumors in mice.

1985 • 7 citations