Characterization of the Human p53 Gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Plasmid screening at high colony density

1980 • 1,100 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1982 • 883 citations

Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

1984 • 761 citations

Participation of p53 cellular tumour antigen in transformation of normal embryonic cells

1984 • 754 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Mutation in LDL Receptor: Alu-Alu Recombination Deletes Exons Encoding Transmembrane and Cytoplasmic Domains

1985 • 453 citations

Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.

1985 • 414 citations

Susceptibility of Human Diploid Fibroblast Strains to Transformation by SV40 Virus

1966 • 343 citations

Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

1985 • 334 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene.

1984 • 297 citations

Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells.

1982 • 279 citations

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene

1984 • 269 citations

Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein.

1981 • 263 citations

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells.

1985 • 227 citations

Overproduction of p53 antigen makes established cells highly tumorigenic

1985 • 217 citations

A single gene and a pseudogene for the cellular tumour antigen p53

1983 • 208 citations

SV40-53K antigen: A possible role for 53K in normal cells

1981 • 187 citations

Analysis of the gene coding for the murine cellular tumour antigen p53.

1984 • 182 citations

Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.

1985 • 174 citations

Radioimmunoassay of the cellular protein p53 in mouse and human cell lines.

1982 • 172 citations

Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types.

1984 • 163 citations

The 5′ region of the p53 gene: evolutionary conservation and evidence for a negative regulatory element.

1985 • 146 citations

Transformation associated p53 protein is encoded by a gene on human chromosome 17

1985 • 77 citations

Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia

1985 • 54 citations

Cellular oncogenes

1984 • 20 citations

In Vitro Expression of Human p53 cDNA Clones and Characterization of the Cloned Human p53 Gene

1985 • 17 citations