Ships ahoy

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1997 • 699 citations

Targeted disruption ofSHIPleads to hemopoietic perturbations, lung pathology, and a shortened life span

1998 • 566 citations

Identification of a Second SH2-Domain-Containing Protein Closely Related to the Phosphatidylinositol Polyphosphate 5-Phosphatase SHIP

1997 • 232 citations

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells

1998 • 158 citations

Growth Factors and Insulin Stimulate Tyrosine Phosphorylation of the 51C/SHIP2 Protein

1998 • 122 citations

The SH2 domain containing inositol 5‐phosphatase SHIP2 displays phosphatidylinositol 3,4,5‐trisphosphate and inositol 1,3,4,5‐tetrakisphosphate 5‐phosphatase activity

1998 • 112 citations

BCR/ABL Directly Inhibits Expression of SHIP, an SH2-Containing Polyinositol-5-Phosphatase Involved in the Regulation of Hematopoiesis

1999 • 111 citations

Negative signaling in B cells causes reduced Ras activity by reducing Shc-Grb2 interactions.

1997 • 94 citations

Cutting Edge: Role of the Inositol Phosphatase SHIP in B Cell Receptor-Induced Ca2+ Oscillatory Response

1998 • 66 citations

A Surprising Function for the PTEN Tumor Suppressor

1998 • 41 citations