Thymic selection

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1991 • 1,090 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1988 • 671 citations

The T Cell Receptor

1987 • 554 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes

1989 • 513 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

Effects of Cyclosporine A on T Cell Development and Clonal Deletion

1988 • 354 citations

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

1991 • 249 citations

The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

1989 • 219 citations

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage

1991 • 209 citations

The Developmental Biology Of T Lymphocytes

1988 • 98 citations