Apoptosis in podocytes induced by TGF-β and Smad7

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1995 • 4,003 citations

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

1997 • 1,774 citations

Control of apoptosis by Rel/NF-κB transcription factors

1999 • 1,204 citations

Rearrangements of the Cytoskeleton and Cell Contacts Induce Process Formation during Differentiation of Conditionally Immortalized Mouse Podocyte Cell Lines

1997 • 867 citations

Synaptopodin: An Actin-associated Protein in Telencephalic Dendrites and Renal Podocytes

1997 • 593 citations

Progression of glomerular diseases: Is the podocyte the culprit?

1998 • 578 citations

A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA.

2000 • 455 citations

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease.

1996 • 423 citations

Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation

1999 • 419 citations

Glomerular cell number in normal subjects and in type 1 diabetic patients

2001 • 394 citations

Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.

1993 • 356 citations

Glomerular hypertrophy and epithelial cell injury modulate progressive glomerulosclerosis in the rat.

1989 • 305 citations

NF-κB inhibition causes spontaneous apoptosis in Epstein–Barr virus-transformed lymphoblastoid cells

2000 • 258 citations

NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis

1998 • 187 citations

Smad3 and Smad4 Mediate Transcriptional Activation of the Human Smad7 Promoter by Transforming Growth Factor β

2000 • 167 citations

Smad7 mediates apoptosis induced by transforming growth factor β in prostatic carcinoma cells

2000 • 135 citations

Pro-apoptotic gene expression mediated by the p38 mitogen-activated protein kinase signal transduction pathway

2001 • 130 citations

Renal Expression of Fibrotic Matrix Proteins and of Transforming Growth Factor-β (TGF-β) Isoforms in TGF-β Transgenic Mice

1999 • 125 citations

Dysfunctions of cell biological mechanisms of visceral epithelial cell (podocytes) in glomerular diseases

1994 • 124 citations

Smad7 inhibits the survival nuclear factor κB and potentiates apoptosis in epithelial cells

2001 • 110 citations

Focal segmental glomerulosclerosis

1996 • 110 citations

Smad proteins and transforming growth factor-β signaling

2000 • 108 citations

Nuclear factor-kappaB/Rel blocks transforming growth factor beta1-induced apoptosis of murine hepatocyte cell lines.

1997 • 95 citations

Induction of p53 and Bax during TGF-β1 Initiated Apoptosis in Rat Liver Epithelial Cells

1998 • 64 citations

Role of caspases and possible involvement of retinoblastoma protein during TGFβ-mediated apoptosis of human B lymphocytes

1999 • 52 citations

DNA array analysis of the developing rat cerebellum: transforming growth factor-β2 inhibits constitutively activated NF-κB in granule neurons

2001 • 26 citations