Distinct Sites of Insulin-Like Growth Factor (IGF)-II Expression and Localization in Lesioned Rat Brain: Possible Roles of IGF Binding Proteins (IGFBPs) in the Mediation of IGF-II Activity

Insulin-like growth factors and their binding proteins: biological actions

1995 • 1,976 citations

Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II

1990 • 529 citations

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1997 • 510 citations

Differential expression of insulin-like growth factor genes in rat central nervous system.

1988 • 477 citations

Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors.

1990 • 441 citations

Receptors for Insulin-like Growth Factors I and II: Autoradiographic Localization in Rat Brain and Comparison to Receptors for Insulin*

1988 • 252 citations

An antibody that blocks insulin-like growth factor (IGF) binding to the type II IGF receptor is neither an agonist nor an inhibitor of IGF-stimulated biologic responses in L6 myoblasts.

1987 • 237 citations

Isolation and Molecular Cloning of Insulin-Like Growth Factor-Binding Protein-6

1991 • 233 citations

Neuroendocrine regulatory mechanisms in the choroid plexus-cerebrospinal fluid system

1992 • 215 citations

Insulin-like growth factor II stimulates calcium influx in competent BALB/c 3T3 cells primed with epidermal growth factor. Characteristics of calcium influx and involvement of GTP-binding protein.

1987 • 192 citations

Localization of binding sites for insulin-like growth factor-I (IGF-I) in the rat brain by quantitative autoradiography

1988 • 179 citations

EVIDENCE FOR TWO SPECIES OF INSULIN-LIKE GROWTH FACTOR II (IGF II AND “BIG” IGF II) IN HUMAN SPINAL FLUID

1982 • 158 citations

Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus

1991 • 146 citations

Identification of an insulin‐like growth factor‐binding protein in human cerebrospinal fluid with a selective affinity for IGF‐II

1986 • 118 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

Characterization of Insulin-Like Growth Factor Binding Proteins Produced in the Rat Central Nervous System*

1990 • 115 citations

Insulin-like growth factors cross the blood-brain barrier

1994 • 107 citations

Type II insulin-like growth factor receptor is present in rat serum.

1987 • 104 citations

Effect of an anti-insulin-like growth factor I receptor antibody on insulin-like growth factor II stimulation of DNA synthesis in human fibroblasts

1986 • 98 citations

The Fetal Rat Binding Protein for Insulin-Like Growth Factors is Expressed in the Choroid Plexus and Cerebrospinal Fluid of Adult Rats

1989 • 94 citations

Mannose 6-phosphate/insulin-like growth factor II-binding proteins in human serum and urine. Their relation to the mannose 6-phosphate/insulin-like growth factor II receptor

1988 • 87 citations

Insulin-like growth factor-binding protein-2 concentrations in cerebrospinal fluid and serum of children with malignant solid tumors or acute leukemia.

1994 • 85 citations

Structural and Immunohistochemical Characterization of Insulin-Like Growth Factor I and II Receptors in the Murine Central Nervous System*

1988 • 84 citations

Insulin‐like growth factor‐I receptors in human brain and pituitary gland: An autoradiographic study

1994 • 62 citations

Expression of insulin‐like growth factor binding protein‐4 and ‐5 mRNAs in adult rat forebrain

1994 • 59 citations

Growth factors in CNS repair and regeneration

1994 • 55 citations

Distribution of Insulin-Like Growth Factor II Receptor Immunoreactivity in Rat Tissues*

1988 • 49 citations

Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting

1992 • 48 citations

Spatial and Temporal Changes in the Insulin-Like Growth Factor (IGF) Axis Indicate Autocrine/Paracrine Actions of IGF-I within Wounds of the Rat Brain

1997 • 47 citations

Expression of insulin-like growth factor-II (IGF-II) and IGF-II/mannose- 6-phosphate receptor in the rat hippocampus: an in situ hybridization and immunocytochemical study

1992 • 34 citations

Insulin-Like Growth Factor II Expression in the Developing Human Brain

1992 • 31 citations

Insulin‐like Growth Factor Binding Proteins in Nervous‐Tissue‐Derived Cells

1993 • 20 citations

Cellular Responses to Penetrating CNS Injury

1998 • 19 citations

Paracrinology of growth regulation.

1991 • 17 citations

Radioimmunohistochemical localization of type II IGF receptors in rat brain

1988 • 17 citations