Antihypertensive Drugs

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

Enzymatic O-Methylation of Epinephrine and Other Catechols

1958 • 1,291 citations

The action of sympathomimetic amines in animals treated with reserpine

1958 • 746 citations

DEPRESSION BY RESERPINE OF THE NORADRENALINE CONCENTRATION IN THE HYPOTHALAMUS OF THE CAT

1956 • 424 citations

Serotonin Release as a Possible Mechanism of Reserpine Action

1955 • 336 citations

Decarboxylase Inhibition and Blood Pressure Reduction by α-Methyl-3,4-Dihydroxy-DL-phenylalanine

1960 • 254 citations

The action of reserpine on the peripheral sympathetic system

1958 • 226 citations

O-Methylation of Catechol Amines in Vivo

1958 • 210 citations

Norepinephrine Depletion as a Possible Mechanism of Action of Guanethidine a New Hypotensive Agent

1960 • 155 citations

The effect of drugs on the amounts of substance P and 5‐hydroxytryptamine in mammalian brain

1956 • 142 citations

Chemical and molecular basis of nerve activity

1960 • 136 citations

CLINICAL AND PHARMACOLOGICAL STUDIES WITH GUANETHIDINE IN THE TREATMENT OF HYPERTENSION

1960 • 120 citations

A NEW, POTENT ANTIHYPERTENSIVE DRUG

1959 • 116 citations

The action of acetylcholine on conduction in mammalian non‐myelinated fibres and its prevention by anticholinesterase

1960 • 101 citations

On the Physiologic Significance of Monoamine Oxidase in Brain

1957 • 97 citations

[2-(Octahydro-1-azocinyl)-ethyl]-guanidine sulfate (CIBA 5864-SU), a new synthetic antihypertensive agent

1959 • 92 citations

Benzo[a]chinolizine, eine neue K�rperklasse mit Wirkung auf den 5-Hydroxytryptamin- und Noradrenalin-Stoffwechsel des Gehirns

1958 • 86 citations

INTERACTION OF MONOAMINE OXIDASE INHIBITORS WITH PHYSIOLOGICAL AND BIOCHEMICAL MECHANISMS IN BRAIN

1959 • 81 citations

Serotonin and Antiserotonins

1957 • 75 citations

SIGNIFICANCE OF SELECTED CENTRAL MECHANISMS FOR THE ANALYSIS OF THE ACTION OF RESERPINE

1955 • 71 citations

Actions of the Decarboxylase Inhibitor, α-Methyl-3,4-dihydroxyphenylalanine, in the Dog

1960 • 71 citations

Effect of Reserpine on the Release of Catecholamines from Isolated Nerve and Chromaffin Cell Granules

1961 • 67 citations

A Suspected Virus Disease of the Citrus Red Mite Panonychus citri (McG.)

1959 • 66 citations

HUMAN PHARMACOLOGY OF RESERPINE

1954 • 64 citations

Release of noradrenaline from adrenergic transmitter granules by tyramine

1960 • 63 citations

MECAMYLAMINE AND ITS MODE OF ACTION

1957 • 61 citations

Paralysis of Autonomic Ganglia and the Therapeutic Effects of Ganglion-blocking Drugs

1951 • 60 citations

Distribution of Acetocholinesterase in the Ganglion Cells of Various Sympathetic Ganglia

1960 • 56 citations

THE CIRCULATORY EFFECTS OF BRETYLIUM TOSYLATE AND GUANETHIDINE

1960 • 53 citations

CLINICAL PHARMACOLOGY OF NEWER ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE AND DECARBOXYLASE INHIBITORS, BRETYLIUM TOSYLATE, AND GUANETHIDINE

1960 • 50 citations

A METHOD FOR MEASUREMENT OF MONOAMINE OXIDASE INHIBITION IN MAN: APPLICATION TO STUDIES ON HYPERTENSION

1959 • 49 citations

SYMPATHOMIMETIC AMINES IN THE CENTRAL NERVOUS SYSTEM

1957 • 49 citations

SELECTIVE DEPLETION OF NORADRENALINE AND 5‐HYDROXYTRYPTAMINE FROM RAT BRAIN AND INTESTINE BY RAUWOLFIA ALKALOIDS*

1959 • 48 citations

Beeinflussung des 5-Hydroxytryptaminstoffwechsels im Gehirn durch Isonikotinsäurehydrazide

1956 • 48 citations

Einfluss von Isopropyl-isonikotinsäurehydrazid auf den Katecholamingehalt des Myokards

1958 • 44 citations

Increase of 5-Hydroxytryptamine in Blood Platelets by Isopropyl-isonicotinic Acid Hydrazide

1958 • 41 citations

Further Characterization of Central Effects of Reserpine (Serpasil)

1955 • 40 citations

Ganglionic Block and Monoamine Oxidase Inhibitors

1959 • 39 citations

Improved Chlorophyll Extraction Method

1960 • 38 citations

The Circulatory Effects of Reserpine

1955 • 37 citations

NEWER BIOCHEMICAL APPROACHES TO THE TREATMENT OF HYPERTENSION

1960 • 35 citations

THE ACTION OF RESERPINE ON THE EXCRETION OF ADRENALINE AND NORADRENALINE

1958 • 35 citations

IPRONIAZID IN CARDIOVASCULAR THERAPY, WITH SPECIAL REFERENCE TO ITS ACTION IN ANGINA PECTORIS AND BLOOD PRESSURE

1959 • 34 citations

PHARMACOLOGY AND CLINICAL USE OF PEMPIDINE IN THE TREATMENT OF HYPERTENSION

1958 • 34 citations

PHARMACOLOGICAL CONSEQUENCES OF SELECTIVE DEPLETION OF CATECHOL AMINES BY ANTIHYPERTENSIVE AGENTS

1960 • 33 citations

THE URINARY EXCRETION OF ADRENALINE AND NORADRENALINE BY SCHIZOPHRENIC PATIENTS DURING RESERPINE TREATMENT

1959 • 32 citations

Selective Depression of Sympathetic Transmission by Intravenous Administration of Iproniazid and Harmine.

1960 • 31 citations

SOME PHARMACOLOGICAL ACTIONS OF BRETYLIUM AND GUANETHIDINE

1960 • 29 citations

Mechanism of Hypotensive Action of Reserpine, an Alkaloid of Rauwolfia serpentina

1954 • 29 citations

Reserpine Derivatives with Specific Hypotensive or Sedative Activity

1959 • 29 citations

SIGNIFICANCE OF MONOAMINE OXIDASE INHIBITION FOR THE PHARMACOLOGICAL AND CLINICAL EFFECTS OF HYDRAZINE DERIVATIVES

1959 • 28 citations

Zur Pharmakologie des N,N,N′,N′-3-Pentamethyl-N,N′-diäthyl-3-aza-pentan-1,5-diammonium-dibromid (Ciba 9295), einer ganglionär hemmenden Substanz

1950 • 28 citations

HUMAN PHARMACOLOGY OF GUANETHIDINE

1960 • 26 citations

INTRAVENOUS RESERPINE IN PATIENTS WITH ESSENTIAL HYPERTENSION

1954 • 26 citations

IN-VITRO FORMATION OF NORADRENALINE FROM DOPAMINE BY HUMAN TISSUE

1957 • 23 citations

PENTACYNIUM BIS-METHYLSULPHATE (PRESIDAL) IN THE MANAGEMENT OF HYPERTENSION

1958 • 22 citations

The Release of Sympathetic Amines by Tyramine from the Aortic Walls of Cats

1960 • 22 citations

The Interruption of Ganglionic Transmission and Some of its Problems

1955 • 21 citations

Effects of various ganglionic blocking agents on blood pressure and on activity of pressor agents

1960 • 20 citations

Rescinnamine in Treatment of Hypertension in Hospital Clinic and in General Practice

1960 • 20 citations

MUSCLE WEAKNESS CAUSED BY BRETYLIUM TOSYLATE

1960 • 17 citations

The Effects of Iproniazid Phosphate (Marsilid) on Hypertension

1957 • 17 citations

New Series of Ganglion-blocking Agents

1956 • 16 citations

Storage of new-formed catecholamines in the adrenal medulla

1960 • 16 citations

CLINICAL PHARMACOLOGY OF BRETYLIUM TOSYLATE: PRELIMINARY OBSERVATIONS

1960 • 15 citations

Powerful Adrenergic Neurone-blocking Agents related to Choline 2,6-Xylyl Ether Bromide

1960 • 15 citations

THE PERIPHERAL DILATOR ACTION OF RESERPINE IN MAN

1960 • 15 citations

Electrophysiological Investigation of Chlorisondamine Dimethochloride (EcolidTM) A New Ganglionic Blocking Agent

1955 • 13 citations

THE ACUTE EFFECTS OF RESERPINE AND OF AMYTAL ON CENTRAL SYMPATHETIC REACTIVITY

1955 • 12 citations

Some Observations on the Pharmacology of 10-Methoxydeserpidine

1960 • 12 citations

PAROTID PAIN DURING TREATMENT WITH BRETYLIUM

1960 • 12 citations

Über die akute und protrahierte Wirkung von Guanethidin auf die Nierenhämodynamik, den Wasser- und Elektrolythaushalt bei gesunden Personen

1960 • 12 citations

Parallelism of Changes Produced by Cooling and by Drugs Known to Affect Adrenergic Mechanisms

1960 • 11 citations

Über eine Strahlenschutzwirkung von Apresolin und C. 5864-Su (2-Octahydro-1-azocynil-äthyl-guanidin)

1960 • 11 citations

Selective Inhibition of the Sympathetic Nervous System in Man with Bretylium Tosylate, a New Antihypertensive Agent

1960 • 11 citations

Effect of reserpine analogues on tissue serotonin

1960 • 9 citations

Two New Ganglion-blocking Agents in Treatment of Hypertension

1956 • 8 citations

HYPOTENSIVE EFFECTS OF IPRONIAZID AND CARBOXAZID

1960 • 8 citations

Weitere Untersuchungen zum Mechanismus der Freisetzung von Brenzeatechinaminen

1961 • 8 citations

EVALUATION OF 2 MONOAMINE OXIDASE INHIBITORS (IPRONIAZID AND JB 516) IN THE THERAPY OF ARTERIAL HYPERTENSION

1959 • 7 citations

THE INTERACTION OF BRETYLIUM WITH PRESSOR AGENTS

1961 • 7 citations

THE COMPARATIVE EFFECTS OF FOUR GANGLIONIC BLOCKING AGENTS ON THE CARDIOVASCULAR SYSTEM OF MAN

1955 • 6 citations

CLINICAL AND EXPERIMENTAL STUDIES ON BRETYLIUM TOSYLATE, A NEW HYPOTENSIVE AGENT

1960 • 5 citations

Hypotensive action of bretylium tosylate (Darenthin)

1960 • 4 citations

A Suggested Effect on Levels of Catecholamina in Brain produced by Small Doses of Reserpine

1960 • 4 citations

A New Orally Effective Long-acting Ganglion-blocking Agent for Hypertension (189c56)

1958 • 3 citations

Comparative Observations of Reserpine and Syrosingopine

1960 • 2 citations

Comparative evaluation of the hypotensive effect of intraspinal and intravenous administration of reserpine

1960 • 2 citations

THE USE OF SYROSINGOPINE (SU-3118) AND HYDRALAZINE IN AMBULATORY HYPERTENSIVE PATIENTS

1960 • 1 citations