Inhibition by Phospholipids of the Interaction between R-ras, Rho, and Their GTPase-Activating Proteins

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

ras GENES

1987 • 3,818 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

Growth factor-like action of phosphatidic acid

1986 • 531 citations

A novel ras-related gene family

1985 • 487 citations

Phosphatidate accumulation in hormone-treated hepatocytes via a phospholipase D mechanism.

1987 • 472 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

Cellular ras activity and phospholipid metabolism

1988 • 331 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

The Effect of GTPase Activating Protein Upon Ras Is Inhibited by Mitogenically Responsive Lipids

1989 • 287 citations

Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins

1989 • 258 citations

Purification of ras GTPase activating protein from bovine brain.

1988 • 255 citations

Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes

1987 • 216 citations

Mutational Analysis of a ras Catalytic Domain

1986 • 36 citations

Characterization of a Factor That Stimulates Hydrolysis of GTP Bound to ras Gene Product p21 (GTPase-Activating Protein) and Correlation of Its Activity to Cell Density

1988 • 8 citations