Distribution of alcohol dehydrogenase mRNA in the rat central nervous system. . Consequences for brain ethanol and retinoid metabolism

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

The Retinoids-Biology, Chemistry and Medicine

1994 • 987 citations

Effects of Moderate Alcohol Consumption on the Central Nervous System*

1998 • 633 citations

Families of retinoid dehydrogenases regulating vitamin A function

2000 • 573 citations

Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures

1999 • 411 citations

Interactions of retinoid binding proteins and enzymes in retinoid metabolism

1999 • 410 citations

Impaired Locomotion and Dopamine Signaling in Retinoid Receptor Mutant Mice

1998 • 357 citations

Molecular Identification of a Major Retinoic‐Acid‐Synthesizing Enzyme, a Retinaldehyde‐Specific Dehydrogenase

1996 • 342 citations

An Essential Role for Retinoid Receptors RARβ and RXRγ In Long-Term Potentiation and Depression

1998 • 316 citations

Relationships within the aldehyde dehydrogenase extended family

1999 • 281 citations

Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family

1999 • 255 citations

Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid

1999 • 253 citations

Physiological Substrates for Rat Alcohol Dehydrogenase Classes: Aldehydes of Lipid Peroxidation, ω-Hydroxyfatty Acids, and Retinoids

1993 • 207 citations

Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system

1990 • 202 citations

Characterization of three isoenzymes of rat alcohol dehydrogenase

1987 • 188 citations

Retinoic Acid Synthesis in Mouse Embryos during Gastrulation and Craniofacial Development Linked to Class IV Alcohol Dehydrogenase Gene Expression

1996 • 179 citations

Metabolic Deficiencies in Alcohol Dehydrogenase Adh1,Adh3, and Adh4 Null Mutant Mice

1999 • 178 citations

Catalytic Efficiency of Human Alcohol Dehydrogenases for Retinol Oxidation and Retinal Reduction

1994 • 172 citations

Role of acetaldehyde in the actions of ethanol on the brain — A review

1996 • 170 citations

Long-term potentiation in rat hippocampus is inhibited by low concentrations of ethanol

1990 • 169 citations

Alcohol dehydrogenase in human tissues: localisation of transcripts coding for five classes of the enzyme

1996 • 144 citations

Cytochrome P4502E (CYP2E) in Brain: Constitutive Expression, Induction by Ethanol and Localization by Fluorescence in Situ Hybridization

2000 • 132 citations

Role of extrahepatic alcohol dehydrogenase in rat ethanol metabolism

1989 • 131 citations

Ethanol metabolism in the brain

1997 • 127 citations

The reaction of astrocytes and neurons in the hippocampus of adult rats during chronic ethanol treatment and correlations to behavioral impairments

1997 • 115 citations

Localization of cellular retinol-binding protein and retinol-binding protein in cells comprising the blood-brain barrier of rat and human.

1990 • 109 citations

Moderate alcohol consumption and loss of cerebellar Prikinje cells

1994 • 101 citations

chi-ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: implications and inferences.

1985 • 98 citations

Contribution to first‐pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family

1998 • 94 citations

DISTRIBUTION OF CATALASE IN RAT BRAIN: AMINERGIC NEURONS AS POSSIBLE TARGETS FOR ETHANOL EFFECTS

1996 • 94 citations

Histochemical Study of Aldehyde Dehydrogenase in the Rat CNS

1991 • 86 citations

Distribution of alcohol and sorbitol dehydrogenases

1993 • 83 citations

A double staining technique for simultaneous demonstration of astrocytes and microglia in brain sections and astroglial cell cultures.

1991 • 79 citations

Ethanol suppresses the induction of long-term potentiation in vivo

1995 • 78 citations

Retinoids, ω‐hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H₂‐receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenase

1998 • 75 citations

Regional Restriction of Alcohol/Retinol Dehydrogenases along the Mouse Gastrointestinal Epithelium

1997 • 72 citations

Separation of aldehyde reductases and alcohol dehydrogenase from brain by affinity chromatography: Metabolism of succinic semialdehyde and ethanol

1975 • 72 citations

Alcohol Dehydrogenase of Class IV (σσ‐ADH) from Human Stomach

1994 • 69 citations

Ocular alcohol dehydrogenase in the rat: Regional distribution and kinetics of the ADH-1 isoenzyme with retinol and retinal

1986 • 69 citations

Retinoid‐binding proteins in the cerebellum and choroid plexus and their relationship to regionalized retinoic acid synthesis and degradation

1998 • 68 citations

Immunohistochemical localization of alcohol dehydrogenase in human kidney, endocrine organs and brain

1983 • 59 citations

Alcohol dehydrogenase of human and rat blood vessels

1997 • 56 citations

Effect of Cellular Retinol-Binding Protein on Retinol Oxidation by Human Class IV Retinol/Alcohol Dehydrogenase and Inhibition by Ethanol

1998 • 55 citations

Adult rabbit brain synthesizes retinoic acid

1993 • 55 citations

Differential sensitivity of cerebellar purkinje neurons to ethanol in selectivity outbred lines of mice: maintenance in vitro independent of synaptic transmission

1983 • 53 citations

EVIDENCE OF ACETALDEHYDE-PROTEIN ADDUCT FORMATION IN RAT BRAIN AFTER LIFELONG CONSUMPTION OF ETHANOL

2000 • 52 citations

Regional Distribution of Low‐K_m Mitochondrial Aldehyde Dehydrogenase in the Rat Central Nervous System

1992 • 48 citations

Retinoic acid synthesis in normal and alzheimer diseased brain and human neural cells

1997 • 45 citations

Structure and expression of the rat class I alcohol dehydrogenase gene

1989 • 45 citations

Immunocytochemistry of Alcohol Dehydrogenase in the Rat Central Nervous System

1989 • 39 citations

A Novel Subtype of Class II Alcohol Dehydrogenase in Rodents

1999 • 37 citations

Molecular Basis for Differential Substrate Specificity in Class IV Alcohol Dehydrogenases

2000 • 36 citations

Aldehyde Dehydrogenase Activities in the Brains of Rats and Mice Genetically Selected for Different Sensitivity to Alcohol

1995 • 34 citations

The ethanol metabolite acetaldehyde inhibits the induction of long‐term potentiation in the rat dentate gyrus in vivo

1999 • 29 citations

Mammalian alcohol dehydrogenase of higher classes: analyses of human ADH5 and rat ADH6

2001 • 17 citations

Initiation of retinoid signaling in primitive streak mouse embryos: Spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis

1997 • 3 citations

Mammalian Alcohol Dehydrogenase – Functional and Structural Implications

2001 • 3 citations