Thymic education

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

FUNCTION OF MACROPHAGES IN ANTIGEN RECOGNITION BY GUINEA PIG T LYMPHOCYTES

1973 • 1,046 citations

The somatic generation of immune recognition

1971 • 974 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES

1973 • 431 citations

H-2 antigens of the thymus determinelymphocyte specificity

1978 • 321 citations

The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytes.

1979 • 268 citations

The Influence of Thymus H-2 Antigens on the Specificity of Maturing Killer and Helper Cells

1978 • 257 citations

T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

1980 • 228 citations

H-2 Mutations: Their Genetics and Effect on Immune Functions

1978 • 200 citations

Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice.

1981 • 165 citations

Specificity of cytotoxic T cells from athymic mice.

1980 • 141 citations

Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts.

1980 • 139 citations

Distribution of H-2 microenvironments in the mouse thymus. Immunoelectron microscopic identification of I-A and H-2K bearing cells.

1980 • 127 citations

Influence of the major histocompatibility complex on lymphocyte interactions in antibody formation

1978 • 48 citations

Functional Activity of T Cells which Differentiate from Nude Mouse Precursors in a Congenic or Allogeneic Thymus Graft

1978 • 41 citations

Interactions of macromolecules on cell membranes and restrictions of T-cell specificity by products of the major histocompatibility complex

1977 • 38 citations

Patterns of virus-immune T-cell responsiveness. Comparison of (H-2(k) x H-2(b)) {arrow} H-2(b) Radiation Chimeras and negatively selected H-2(b) lymphocytes

1979 • 23 citations

Sendai virus-specific, H-2-restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands.

1980 • 22 citations

MHC restriction, self-tolerance and the thymus

1980 • 12 citations