An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

Invasive Group A Streptococcal Infections in Ontario, Canada

1996 • 725 citations

Intravenous Immunoglobulin Therapy for Streptococcal Toxic Shock Syndrome—A Comparative Observational Study

1999 • 537 citations

Population-Based Surveillance for Group A Streptococcal Necrotizing Fasciitis: Clinical Features, Prognostic Indicators, and Microbiologic Analysis of Seventy-Seven Cases

1997 • 492 citations

The Changing Epidemiology of Invasive Group A Streptococcal Infections and the Emergence of Streptococcal Toxic Shock-like Syndrome

1993 • 394 citations

Bacterial pyrogenic exotoxins as superantigens

1995 • 281 citations

Genetic Relatedness and Superantigen Expression in Group A Streptococcus Serotype M1 Isolates from Patients with Severe and Nonsevere Invasive Diseases

2000 • 274 citations

HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.

1990 • 253 citations

Streptococcal Serogroup: A Epidemic in Norway 1987–1988

1990 • 226 citations

The serotypes of Streptococcus pyogenes present in Britain during 1980-1990 and their association with disease

1993 • 213 citations

Outbreak of Group A Streptococcal Bacteremia in Sweden: An Epidemiologic and Clinical Study

1991 • 159 citations

Risk Factors in the Pathogenesis of Invasive Group A Streptococcal Infections: Role of Protective Humoral Immunity

1999 • 142 citations

Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infection

2000 • 132 citations

Evidence for Superantigen Involvement in Severe Group A Streptococcal Tissue Infections

2001 • 127 citations

HLA Class II Associations With Rheumatic Heart Disease Are More Evident and Consistent Among Clinically Homogeneous Patients

1999 • 119 citations

Selective Depletion Of V -Bearing T Cells In Patients With Severe Invasive Group A Streptococcal Infections And Streptococcal Toxic Shock Syndrome

1995 • 116 citations

Genetics and genomics of infectious disease susceptibility

1999 • 86 citations

Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates

1997 • 55 citations

Mutations in the MHC class II binding domains of staphylococcal enterotoxin A differentially affect T cell receptor Vbeta specificity.

1996 • 50 citations

CD28 cross-linking augments TCR-mediated signals and costimulates superantigen responses.

1995 • 33 citations