Cellular and Molecular Aspects of Myelin Protein Gene Expression

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

1981 • 1,265 citations

PROTEOLIPIDES, A NEW TYPE OF TISSUE LIPOPROTEINS

1951 • 773 citations

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1

1984 • 723 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

X‐CHROMOSOME INACTIVATION AND DEVELOPMENTAL PATTERNS IN MAMMALS

1972 • 657 citations

Mutant Mice (Quaking and Jimpy) with Deficient Myelination in the Central Nervous System

1964 • 607 citations

The J1 glycoprotein—a novel nervous system cell adhesion molecule of the L2/HNK-1 family

1985 • 590 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve.

1986 • 482 citations

THE REGIONAL AND SUBCELLULAR DISTRIBUTION OF 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE IN THE CENTRAL NERVOUS SYSTEM

1967 • 458 citations

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

1986 • 456 citations

Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1

1983 • 431 citations

Synthesis and incorporation of myelin polypeptides into CNS myelin.

1982 • 422 citations

Expression of a myelin basic protein gene in transgenic shiverer mice: Correction of the dysmyelinating phenotype

1987 • 389 citations

Characterization of cloned cDNA representing rat myelin basic protein: Absence of expression in brain of shiverer mutant mice

1983 • 382 citations

The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily

1987 • 370 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve I. Cell proliferation

1976 • 364 citations

Myelin-associated glycoprotein demonstrated immunocytochemically in myelin and myelin-forming cells of developing rat.

1979 • 360 citations

Nucleotide sequences of two mRNAs for rat brain myelin proteolipid protein

1985 • 345 citations

Maturation of human white matter myelin. Fractionation of the myelin membrane proteins

1968 • 343 citations

Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.

1984 • 336 citations

Emergence of three myelin proteins in oligodendrocytes cultured without neurons.

1986 • 333 citations

Chromosomal mapping of mouse myelin basic protein gene and structure and transcription of the partially deleted gene in shiverer mutant mice

1985 • 331 citations

Electron microscopic autoradiographic studies of gliogenesis in rat optic nerve. II. Time of origin

1976 • 315 citations

Alternative splicing accounts for the four forms of myelin basic protein

1985 • 306 citations

QUAKING MOUSE: ISOLATION AND CHARACTERIZATION OF MYELIN PROTEIN

1971 • 305 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

Absence of the major dense line in myelin of the mutant mouse ‘shiverer’

1979 • 299 citations

Reconstitution of a developmental clock in vitro: a critical role for astrocytes in the timing of oligodendrocyte differentiation

1985 • 296 citations

Molecular cloning and primary structure of myelin-associated glycoprotein.

1987 • 284 citations

The fine structure of the nervous system : the cells and their processes

1970 • 277 citations

Myelin basic protein demonstrated immunocytochemically in oligodendroglia prior to myelin sheath formation.

1978 • 270 citations

Differentiation of a bipotential glial progenitor cell in single cell microculture

1985 • 262 citations

Immunocytochemical method to identify basic protein in myelin-forming oligodendrocytes of newborn rat C.N.S.

1978 • 257 citations

PATHOGENESIS OF SUBACUTE COMBINED DEGENERATION: A RESULT OF METHYL GROUP DEFICIENCY

1981 • 248 citations

Neurological Mutations Affecting Myelination

1981 • 242 citations

Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons

1985 • 234 citations

Isolation and Characterization of Myelin

1984 • 223 citations

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

1986 • 219 citations

Oligodendroglial cell death in jimpy mice: an explanation for the myelin deficit

1986 • 218 citations

PARTIAL CHARACTERIZATION OF A NEW MYELIN PROTEIN COMPONENT

1972 • 214 citations

Assignment of the Gene for Myelin Proteolipid Protein to the X Chromosome: Implications for X-Linked Myelin Disorders

1985 • 213 citations

Functionally Differentiated Cell Lines

1982 • 213 citations

Immunochemical studies of myelin basic protein in shiverer mouse devoid of major dense line of myelin

1979 • 210 citations

Presence of the myelin-associated glycoprotein correlates with alterations in the periodicity of peripheral myelin.

1982 • 207 citations

Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin

1971 • 197 citations

The effect of neonatal thyroidectomy on myelination in the rat brain

1969 • 195 citations

Myelin deficient mice: Expression of myelin basic protein and generation of mice with varying levels of myelin

1987 • 194 citations

Transplantation of CNS Fragments into the Brain of Shiverer Mutant Mice: Extensive Myelination by Implanted Oligodendrocytes

1983 • 191 citations

CHANGES IN THE PROTEIN COMPOSITION OF MOUSE BRAIN MYELIN DURING DEVELOPMENT

1972 • 188 citations

Identifying the protein products of brain-specific genes with antibodies to chemically synthesized peptides

1983 • 188 citations

Shiverer: an autosomal recessive mutant mouse with myelin deficiency

1981 • 187 citations

2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE IN BRAINS OF MUTANT MICE WITH DEFICIENT MYELINATION

1970 • 185 citations

Individual exons encode the integral membrane domains of human myelin proteolipid protein.

1986 • 177 citations

Properties, Structure and Possible Neuroreceptor Role of the Encephalitogenic Protein of Human Brain

1971 • 175 citations

Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

1987 • 174 citations

Myelin-Associated Glycoprotein in Development and Disease

1983 • 172 citations

Identification of three forms of human myelin basic protein by cDNA cloning.

1986 • 161 citations

Myelin deficit in the Jimpy mouse may be due to cellular abnormalities in astroglia

1976 • 160 citations

Amino acid sequence of the smaller basic protein from rat brain myelin

1974 • 159 citations

Animal Models of Genetic Disorders of Myelin

1984 • 159 citations

Identification of prelarge and presmall basic proteins in mouse myelin and their structural relationship to large and small basic proteins

1977 • 158 citations

The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice

1986 • 154 citations

2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHOHYDROLASE IN THE DEVELOPING CHICK BRAIN AND SPINAL CORD

1968 • 153 citations

Isolation of a highly purified myelin protein

1971 • 150 citations

ACCUMULATION OF THE FOUR MYELIN BASIC PROTEINS IN MOUSE BRAIN DURING DEVELOPMENT¹

1978 • 149 citations

The turnover of myelin in the adult rat

1968 • 149 citations

In Vitro and in Vivo Phosphorylation of Myelin Basic Protein by Exogenous and Endogenous Adenosine 3′ : 5′-Monophosphate-dependent Protein Kinases in Brain

1974 • 145 citations

Recombination within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation.

1986 • 143 citations

On the type of linkage binding fatty acids present in brain white matter proteolipid apoprotein

1971 • 139 citations

Localization of Methylated Arginine in the A1 Protein from Myelin

1971 • 138 citations

Developmental regulation of myelin basic protein expression in mouse brain

1983 • 138 citations

Survival and differentiation of oligodendrocytes from neural tissue transplanted into new-born mouse brain

1983 • 132 citations

Identification of a cDNA coding for a fifth form of myelin basic protein in mouse.

1987 • 132 citations

A NEW PROTEOLIPID FRACTION OF THE NERVOUS. SYSTEM *–I.

1966 • 131 citations

Structure and expression of the mouse myelin proteolipid protein gene

1987 • 130 citations

ACTIVITY OF 2′,3′‐CYCLIC‐NUCLEOTIDE 3′‐PHOSPHODIESTERASE IN REGIONS OF RAT BRAIN DURING DEVELOPMENT: QUANTITATIVE RELATIONSHIP TO MYELIN BASIC PROTEIN

1978 • 126 citations

Interactions of lipids with a membrane structural protein from myelin

1969 • 126 citations

Increased proliferation of oligodendrocytes in the hypomyelinated mouse mutant-jimpy

1982 • 123 citations

Fine structure of the central myelin sheath in the myelin deficient mutant Shiverer mouse, with special reference to the pattern of myelin formation by oligodendroglia

1981 • 122 citations

Amino Acid Sequence of the Basic Protein of the Myelin Membrane

1970 • 120 citations

Characterization of mouse myelin basic protein messenger RNAs with a myelin basic protein cDNA clone.

1984 • 118 citations

Oligodendrocyte Adhesion Activates Protein Kinase C-Mediated Phosphorylation of Myelin Basic Protein

1986 • 117 citations

Phosphorylation of selected serine and threonine residues in myelin basic protein by endogenous and exogenous protein kinases

1974 • 115 citations

Quaking mouse: ultrastructural evidence for arrest of myelinogenesis

1971 • 115 citations

Proteins of myelin and their metabolism

1978 • 115 citations

Developmental Expression of the Myelin Proteolipid Protein and Basic Protein mRNAs in Normal and Dysmyelinating Mutant Mice

1987 • 112 citations

INFLUENCE OF THYROID ON FORMATION OF MYELIN LIPIDS ¹

1969 • 112 citations

Predicted Folding of β‐Structure in Myelin Basic Protein

1984 • 111 citations

Developmental regulation of myelin basic protein in dispersed cultures

1981 • 111 citations

Maintenance of isolated oligodendrocytes in long-term culture

1980 • 110 citations

Identification of multiple in vivo phosphorylation sites in rabbit myelin basic protein.

1983 • 109 citations

Triiodothyronine Stimulation of Oligodendroglial Differentiation and Myelination

1985 • 106 citations

Two developmentally regulated messenger RNAs differing in their coding region may exist for the myelin-associated glycoprotein.

1984 • 105 citations

Investigations on myelination in vitro. Regulation by thyroid hormone in cultures of dissociated brain cells from embryonic mice.

1979 • 104 citations

Myelinogenesis in optic nerve. A morphological, autoradiographic, and biochemical analysis.

1977 • 103 citations

Differences between the two myelin basic proteins of the rat central nervous system

1972 • 101 citations

Oligodendroglial cell development in jimpy mice and controls

1975 • 98 citations

Studies on the Wolfgram High Molecular Weight CNS Myelin Proteins: Relationship to 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase

1980 • 97 citations

Phosphorylation of Myelin Basic Protein

1974 • 97 citations

S-Adenosylmethionine:protein-arginine methyltransferase. Purification and mechanism of the enzyme

1977 • 95 citations

Expression of Myelin Proteolipid Protein and Basic Protein in Normal and Dysmyelinating Mutant Mice

1986 • 93 citations

Ontogenetic study of a myelin-derived fraction with 2′:3′-cyclic nucleotide 3′-phosphodydrolase activity higher than that of myelin

1975 • 91 citations

Molecular Genetic Analysis of Myelin‐Deficient Mice: Shiverer Mutant Mice Show Deletion in Gene(s) Coding for Myelin Basic Protein

1985 • 89 citations

Requirement for nonoligodendrocyte cell signals for enhanced myelinogenic gene expression in long-term cultures of purified rat oligodendrocytes.

1981 • 89 citations

Gel electrophoresis studies of bovine brain white matter proteolipid and myelin proteins

1974 • 89 citations

2′, 3′-Cyclic nucleotide 3′-phosphohydrolase in the brain of the “Jimpy” mouse, a mutant with deficient myelination

1969 • 89 citations

Comparison of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and the Major Component of Wolfgram Protein W1

1980 • 88 citations

A neurological mutation (msd) of the mouse causing a deficiency of myelin synthesis

1970 • 87 citations

Oligodendroglial Expression and Deposition of Four Major Myelin Constituents in the Myelin Sheath during Development

1986 • 85 citations

Expression of myelin proteolipid and basic protein mRNAS in cultured cells

1986 • 83 citations

Brain proteolipids in neurological mutant mice

1973 • 82 citations

Synthesis of myelin basic proteins in the developing mouse brain

1978 • 81 citations

Investigations on myelination in vitro. Regulation of sulfolipid synthesis by thyroid hormone in cultures of dissociated brain cells from embryonic mice.

1981 • 81 citations

In vitro acylation of rat brain myelin proteolipid protein.

1982 • 80 citations

The Immunological Identification of Brain Proteins on Cellulose Nitrate in Human Demyelinating Disease

1982 • 80 citations

Purification and partial characterization of the myelin-associated glycoprotein from adult rat brain

1983 • 79 citations

Phosphate groups modifying myelin basic proteins are metabolically labile; methyl groups are stable.

1983 • 76 citations

Incorporation of [35S]sulphate into brain constituents during development and the effects of thyroid hormone on myelination

1971 • 75 citations

The gene encoding for the major brain proteolipid (PLP) maps on the q-22 band of the human X chromosome

1986 • 74 citations

Evidence for the expression of four myelin basic protein variants in the developing human spinal cord through cDNA cloning

1987 • 73 citations

An Ultrastructural Study of Subacute Combined Degeneration of the Spinal Cord in Vitamin B12-Deficient Rhesus Monkeys

1978 • 72 citations

Myelin proteolipid protein (PLP and DM-20) transcripts are deleted in jimpy mutant mice.

1986 • 71 citations

Biochemical changes in mouse brain composition during myelination

1973 • 71 citations

Characterization of myelin proteolipid mRNAs in normal and jimpy mice.

1986 • 69 citations

Transplantations of Newborn CNS Fragments into the Brain of Shiverer Mutant Mice: Extensive Myelination by Transplanted Oligodendrocytes

1986 • 68 citations

Synthesis of a myelin‐like membrane by oligodendrocytes in culture

1986 • 67 citations

Protein determinants of myelination in different regions of developing rat central nervous system

1977 • 67 citations

Expression of mosaicism in females heterozygous for Jimpy

1981 • 66 citations

Regional distribution of myelin basic protein in the central nervous system of quaking, jimpy, and normal mice during development and aging

1981 • 66 citations

Noncoordinate regulation of myelinogenic parameters in primary cultures of dissociated fetal rat brain

1981 • 66 citations

Mature Oligodendrocytes Cultured in the Absence of Neurons Recapitulate the Ontogenic Development of Myelin Membranes

1986 • 65 citations

Expression of myelin proteins in the developing human spinal cord: Cloning and sequencing of human proteolipid protein cDNA

1987 • 64 citations

Study of the expression of myelin proteolipid protein (lipophilin) using a cloned complementary DNA

1985 • 63 citations

Myelin‐Associated Glycoprotein: Electron Microscopic Immunocytochemical Localization in Compact Developing and Adult Central Nervous System Myelin

1983 • 62 citations

Myelin Basic Protein Deposition in the Optic and Sciatic Nerves of Dysmyelinating Mutants Quaking, Jimpy, Trembler, MLD, and Shiverer During Development

1983 • 62 citations

Effect of the Jimpy Mutation on Expression of Myelin Proteins in Heterozygous and Hemizygous Mouse Brain

1984 • 61 citations

In vivo acylation of rat brain myelin proteolipid protein.

1982 • 61 citations

The Effect of the Shiverer Mutation on Myelin Basic Protein Expression in Homozygous and Heterozygous Mouse Brain

1983 • 61 citations

Density Profile and Basic Protein Measurements in the Myelin Range of Particulate Material from Normal Developing Mouse Brain and from Neurological Mutants (Jimpy; Quaking; Trembler; Shiverer and its mid Allele) Obtained by Zonal Centrifugation

1980 • 61 citations

Myelin

1984 • 61 citations

Myelin‐Associated Galactolipids in Primary Cultures from Dissociated Fetal Rat Brain: Biosynthesis, Accumulation, and Cell Surface Expression

1985 • 60 citations

Molecular cloning and nucleotide sequence of a cDNA clone coding for rat brain myelin proteolipid

1985 • 58 citations

Impulse Conduction Regulates Myelin Basic Protein Phosphorylation in Rat Optic Nerve

1984 • 58 citations

Investigations on Myelination In Vitro: Regulation of 2′,3′‐Cyclic Nucleotide 3′‐Phosphohydrolase by Thyroid Hormone in Cultures of Dissociated Brain Cells from Embryonic Mice

1982 • 58 citations

Myelin‐Deficient Rat: Analysis of Myelin Proteins

1986 • 58 citations

METABOLIC RELATIONSHIPS BETWEEN MYELIN SUBFRACTIONS: ENTRY OF PROTEINS ¹

1976 • 58 citations

Phospholipid‐Sensitive Ca²⁺‐Dependent Protein Kinase Preferentially Phosphorylates Serine‐115 of Bovine Myelin Basic Protein

1984 • 57 citations

Abnormal Expression of the Myelin‐Associated Glycoprotein in the Central Nervous System of Dysmyelinating Mutant Mice

1985 • 57 citations

BIOCHEMICAL CHARACTERIZATION OF A MYELIN FRACTION ISOLATED FROM RAT BRAIN AGGREGATING CELL CULTURES

1979 • 57 citations

Myelin deficient, a new neurological mutant in the mouse

1977 • 56 citations

Effects of Monensin on Posttranslational Processing of Myelin Proteins

1983 • 56 citations

External labeling of galactose in surface membrane glycoproteins of the intact myelin sheath.

1976 • 56 citations

Ca2+-Calmodulin dependent phosphorylation of myelin isolated from rabbit brain

1980 • 55 citations

Characterization of a subset of oligodendrocytes separated on the basis of selective adherence properties

1984 • 55 citations

Calcium ion stimulated endogenous protein kinase catalyzed phosphorylation of basic proteins in myelin subfractions and myelin-like membrane fraction from rat brain

1980 • 55 citations

Cell‐Free Synthesis of Myelin Basic Proteins in Normal and Dysmyelinating Mutant Mice

1984 • 55 citations

Developmental expression of 2′,3′ ‐cyclic nucleotide 3′ ‐phosphohydrolase in dissociated fetal rat brain cultures and rat brain

1985 • 55 citations

2′-3′-cyclic nucleotide 3′-phosphohydrolase activity in the central nervous system of a myelin deficient mutant (Shiverer)

1980 • 55 citations

Cultured oligodendrocytes. A role for cell-substratum interaction in phenotypic expression.

1986 • 54 citations

Subcellular Distribution and Developmental Change of 2′,3′‐Cyclic Nucleotide 3′‐Phosphohydrolase in the Central Nervous System of the Myelin‐Deficient Shiverer Mutant Mice

1980 • 54 citations

The myelin deficit in quaking mice

1974 • 54 citations

In Vitro Synthesis of the Four Mouse Myelin Basic Proteins: Evidence for the Lack of a Metabolic Relationship

1982 • 53 citations

CYTOPATHIC EFFECTS OF VISNA VIRUS IN CULTURED MAMMALIAN NERVOUS TISSUE

1969 • 52 citations

Phosphorylation in vivo of four basic proteins of rat brain myelin

1982 • 52 citations

MYELIN PROTEINS FROM DIFFERENT REGIONS OF THE CENTRAL NERVOUS SYSTEM

1974 • 51 citations

Lipid metabolism of isolated oligodendrocytes maintained in long-term culture mimics events associated with myelinogenesis.

1983 • 49 citations

Detection of various forms of brain myelin basic protein in vertebrates by electroimmunoblotting

1984 • 49 citations

Appearance of Myelin Proteins during Development in the Chick Central Nervous System

1985 • 49 citations

Protein composition of myelin from brain and spinal cord of several species

1973 • 48 citations

Jimpy Mice: Quantitation of Myelin‐Associated Glycoprotein and Other Proteins

1986 • 48 citations

Localization of the human myelin basic protein gene <i>(MBP)</i> to region 18q22→qter by in situ hybridization

1985 • 48 citations

Inefficient Transcription of the Myelin Basic Protein Gene Possibly Causes Hypomyelination in Myelin‐Deficient Mutant Mice

1987 • 48 citations

Acylation of endogenous myelin proteolipid protein with different acyl-CoAs.

1987 • 48 citations

Shiverer gene maps near the distal end of chromosome 18 in the house mouse

1985 • 48 citations

Isolation and characterization of a cDNA coding for a novel human 17.3k myelin basic protein (MBP) variant

1986 • 47 citations

Radioautographic evidence for the protracted proliferation of glial cells in the central nervous system of jimpy mice

1981 • 46 citations

Correlation between inhibition of myelin basic protein (arginine) methyltransferase by sinefungoin and lack of compact myelin formation in cultures of cerebral cells from embryonic mice

1986 • 45 citations

In Vitro Synthesis of the Myelin Basic Proteins: Subcellular Site of Synthesis

1980 • 45 citations

Use of chimeras to transmit lethal genes in the mouse and to demonstrate allelism of the two X‐linked male lethal genes jp and msd

1973 • 44 citations

Abnormal metabolic response to excess potassium in astrocytes from the Jimpy mouse, a convulsing neurological mutant

1980 • 44 citations

METHYLASES OF MYELIN BASIC PROTEIN AND HISTONE IN RAT BRAIN

1975 • 44 citations

Localization of Glycoconjugates Recognized by the HNK-1 Antibody in Mouse and Chick Embryos during Early Neural Development

1987 • 43 citations

Isolation of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase from Human Brain

1980 • 43 citations

Shiverer*jimpy double mutant mice. I. Biochemical evidence for reciprocal intergenic suppression

1986 • 42 citations

cDNA cloning and amino acid sequence of bovine brain 2',3'-cyclic-nucleotide 3'-phosphodiesterase.

1987 • 42 citations

Effects of altered thyroid function on galactosyl diacylglycerol metabolism in myelinating rat brain.

1977 • 42 citations

Investigations on myelination in vitro: IV. „Myelin‐Like”︁ or Premyelin Structures in Cultures of Dissociated Brain Cells From 14–15‐Day‐Old Embryonic Mice

1983 • 41 citations

Expression of Myelin Basic Protein Genes in Several Dysmyelinating Mouse Mutants During Early Postnatal Brain Development

1985 • 41 citations

Small basic proteins of myelin from central and peripheral nervous systems are encoded by the same gene.

1986 • 40 citations

Myelination by transplanted fetal and neonatal oligodendrocytes in a dysmyelinating mutant

1986 • 40 citations

In vitro and in vivo phosphorylation of myelin basic protein by cerebral protein kinase

1974 • 39 citations

Linkage relationships of markers on chromosome 17 of the house mouse

1975 • 39 citations

PROTEOLIPIDS IN THE DEVELOPING BRAINS OF NORMAL MICE AND MYELIN DEFICIENT MUTANTS¹

1974 • 39 citations

Cycloleucine-induced vacuolation of myelin is associated with inhibition of protein methylation

1981 • 39 citations

Abnormal cell relationships in Jimpy mice: electron microscopic and immunocytochemical findings

1983 • 39 citations

In vivo phosphorylation of two myelin basic proteins of developing rabbit brain.

1981 • 38 citations

Oligodendrocytes, key cells in myelination and target in demyelinating diseases

1985 • 38 citations

APPEARANCE OF NEWLY SYNTHESIZED PROTEIN IN MYELIN OF YOUNG RATS¹

1975 • 38 citations

Patterns of Oligodendrocyte Function Seen by Immunocytochemistry

1984 • 38 citations

Stimulation of oligodendrocytes by extracts from astrocyte‐enriched cultures

1986 • 38 citations

Intracellular localization of 2′,3′-cyclic nucleotide 3′-phosphohydrolase in rat oligodendrocytes and C6 glioma cells, and effect of cell maturation and enzyme induction on localization

1984 • 37 citations

Synthesis of the myelin proteolipid protein in the developing mouse brain

1980 • 37 citations

Oligodendrocyte abnormalities in shiverer mouse mutant are determined in primary chimaeras

1982 • 37 citations

The differentiation of synthesis from incorporation of basic protein in quaking mutant mouse myelin

1977 • 37 citations

Effects of neuron-conditioned medium and fetal calf serum content on glial growth in dissociated cultures

1986 • 37 citations

Myelin-associated glycoprotein and myelinating Schwann cell-axon interaction in chronic B,B'-iminodipropionitrile neuropathy.

1984 • 36 citations

Myelin-Associated Enzymes

1983 • 35 citations

Evidence for defective incorporation of proteins in myelin of the quaking mutant mouse

1977 • 35 citations

Regulation of Myelin Basic Protein (Arginine) Methyltransferase by Thyroid Hormone in Myelinogenic Cultures of Cells Dissociated from Embryonic Mouse Brain

1984 • 35 citations

Myelin proteolipid protein is not esterified at the site of synthesis

1983 • 34 citations

The Relationship of Myelin Basic Protein (Arginine) Methyltransferase to Myelination in Mouse Spinal Cord

1982 • 34 citations

Studies of human myelin proteins during old age

1980 • 34 citations

Studies on myelin-basic-protein methylation during mouse brain development

1986 • 33 citations

Hypomyelinated mutant mice. II. Myelination in vitro

1980 • 33 citations

Investigations on myelinogenesis in vitro: A study of the critical period at which thyroid hormone exerts its maximum regulatory effect on the developmental experession of two myelin associated markers in cultured brain cells from embryonic mice

1985 • 33 citations

Synthesis of myelin glycosphingolipids by isolated oligodendrocytes in tissue culture

1981 • 33 citations

Myelin basic protein gene expression in quaking, jimpy, and myelin synthesis-deficient mice

1984 • 32 citations

Metabolism of a myelin-associated glycoprotein in developing rat brain

1974 • 32 citations

In vivo Phosphorylation of Myelin Basic Proteins in Developing Mouse Brain: Evidence that Phosphorylation Is an Early Event in Myelin Formation

1983 • 32 citations

Electroblot Analysis of Rat Myelin Proteolipid Protein and Basic Protein during Development

1983 • 31 citations

Intracellular translocation of newly synthesized myelin proteins in the rat brain stem slices

1981 • 31 citations

Similarities and dissimilarities between two myelin deficient mutant mice, Shiverer andmld

1981 • 31 citations

Myelin: Chemistry and biology

1981 • 31 citations

Developmental change in a myelin-associated glycoprotein: a comparative study in rodents

1974 • 31 citations

Acylation of Rat Brain Myelin Proteolipid Protein with Different Fatty Acids

1986 • 30 citations

Factors affecting the electrophoretic analysis of myelin proteins: Application to changes occurring during brain development

1977 • 30 citations

Myelin instability and oligodendrocyte metabolism in myelin-deficient mutant mice.

1986 • 30 citations

Mice heterozygous for the mld mutation have intermediate levels of myelin basic protein mRNA and its translation products

1986 • 29 citations

Hypomyelinated mutant mice. V. Relationship between jp and jpmsd re-examined on identical genetic backgrounds

1983 • 29 citations

The genes for myelin

1987 • 29 citations

Lipophilin (PLP) Gene in X‐linked myelin disorders

1986 • 29 citations

Analysis of the Primary Structure of the Strongly Hydrophobic Brain Myelin Proteolipid Apoprotein (Lipophilin). Isolation and Amino Acid Sequence Determination of Proteolytic Fragments

1982 • 28 citations

Biochemical and immunohistochemical studies on dysmyelination of quaking mutant mice in vivo and in vitro

1979 • 28 citations

Expression of the jimpy gene in the spinal cords of heterozygous female mice. I. An early myelin deficit followed by compensation

1986 • 28 citations

Regulation of myelin basic protein in oligodendrocytes by a soluble neuronal factor

1986 • 27 citations

Intrinsic Myelin Proteins Are Normally Synthesized in vitro in the Myelin-Deficient (mld)Mutant Mouse

1983 • 27 citations

Studies on myelin basic protein-specific protein methylase I in various dysmyelinating mutant mice

1984 • 27 citations

Translational regulation of myelin basic protein synthesis

1987 • 26 citations

Investigations on myelinogenesis in vitro: Developmental expression of myelin basic protein mRNA and its regulation by thyroid hormone in primary cerebral cell cultures from embryonic mice

1987 • 26 citations

Oligodendroglial structures and distribution shown by carbonic anhydrase immunostaining in the spinal cords of developing normal and shiverer mice

1985 • 26 citations

Effect of thyroid hormone on the synthesis of sialosyl galactosylceramide (GM4) in myelinogenic cultures of cells dissociated from embryonic mouse brain

1983 • 26 citations

Assignment of the myelin basic protein gene to human chromosome 18q22-qter

1987 • 26 citations

Purification and characterization of minor brain proteolipids: use of fast atom bombardment — mass spectrometry for peptide sequencing

1986 • 25 citations

Developmental changes in the basic proteins of normal and jimpy mouse brain

1972 • 25 citations

PURIFICATION OF 2′,3′‐CYCLIC NUCLEOTIDE 3′‐PHOSPHOHYDROLASE FROM BOVINE BRAIN BY IMMUNOAFFINITY CHROMATOGRAPHY: FURTHER BIOCHEMICAL CHARACTERIZATION OF THE PROTEIN

1979 • 25 citations

In Vivo Methylation of an Arginine in Chicken Myelin Basic Protein

1982 • 25 citations

Correlative biochemical and morphological studies of myelination in human ontogenesis

1980 • 25 citations

Low myelin basic protein levels and normal myelin in peripheral nerves of myelin deficient mutant mice (MLD)

1980 • 24 citations

PROTEOLIPID PROTEIN: SYNTHESIS AND ASSEMBLY INTO QUAKING MOUSE MYELIN

1979 • 23 citations

Myelination ofjp,jpmsd andqk axons by normal glia in vitro: Ultrastructural and autoradiographic evidence

1983 • 23 citations

Arylsulphatase a and 2',3'-cyclic nucleotide 3'-phosphohydrolase activities in the brains of myelin deficient mutant mice

1976 • 22 citations

Myelin‐Associated Glycoprotein in the Central and Peripheral Nervous System of Quaking Mice

1987 • 22 citations

Hypomyelinated mutant mice. III. Increased myelination in mutant cerebellum co-cultured with normal optic nerve

1981 • 20 citations

Biosynthesis and insertion of Wolfgram protein into optic nerve membranes

1985 • 20 citations

Shiverer*jimpy double mutant mice. II. Morphological evidence supports reciprocal intergenic suppression

1986 • 20 citations

Protein composition in developing human brain myelin

1974 • 19 citations

In vitro myelin basic protein synthesis in the PNS and CNS of myelin deficient (mld) mutant mice

1983 • 19 citations

In vivo phosphorylation of myelin basic proteins: Age-related differences in 32P incorporation

1986 • 19 citations

Investigations on myelinogenesis in vitro: Regulation of 5′‐nucleotidase activity by thyroid hormone in cultures of dissociated cells from embryonic mouse brain

1984 • 18 citations

Biochemical Expression of Mosaicism in Female Mice Heterozygous for the Jimpy Gene

1984 • 18 citations

Distribution of myelin-associated enzymes and myelin proteins into membrane fractions from the brains of adult shiverer and control (+/+) mice

1983 • 18 citations

In vivo acylation of proteolipid protein and DM-20 in myelin and myelin subfractions of developing rat brain: Immunoblot identification of acylated PLP and DM-20

1983 • 18 citations

Oligodendroglia

1984 • 18 citations

A New Form of Myelin Basic Protein Found in Human Brain

1986 • 17 citations

A regional study of developing rat brain: The accumulation and distribution of proteolipid proteins

1976 • 16 citations

Phosphorylation of myelin basic protein by vaccinia virus cores

1976 • 16 citations

Calcium- and cyclic AMP-regulated protein kinases of bovine central-nervous-system myelin

1984 • 16 citations

Glial differentiation in dissociated cell cultures of neonatal rat brain: Noncoordinate and density‐dependent regulation of oligodendroglial enzymes

1986 • 16 citations

Phosphorylation of mylein basic protein by glycogen phosphorylase kinase

1984 • 15 citations

In vivo phosphorylation of myelin basic proteins: Single and double isotope incorporation in developmentally related myelin fractions

1986 • 15 citations

Developmental alterations in molecular weights of proteins in the human central nervous system that react with antibodies against myelin-associated glycoprotein.

1984 • 15 citations

Immunohistochemical Localization of 2′,3′‐Cyclic Nucleotide 3′‐Phosphodiesterase and Myelin Basic Protein in the Central Nervous System of the Jimpy and the Normal Mouse

1985 • 15 citations

Myelin‐associated glycoprotein (MAG) in the CNS of adult shiverer (Shi/Shi) mice

1986 • 15 citations

Partial deficiencies in the myelin proteins of developing mice heterozygous for the shiverer mutation

1982 • 14 citations

Simultaneously entry of palmitic acid into proteolipid protein in different myelin subfractions of rat brain

1984 • 14 citations

Biochemical Correlates of Myelination in Brain and Spinal Cord of Mice Heterozygous for the Jimpy Gene

1986 • 14 citations

Biochemical and Immunocytochemical Evidence for a Deficiency of Normal Interfascicular Oligodendroglia in the CNS of the Dysmyelinating Mutant (md) Rat

1986 • 14 citations

Oligodendrocyte production and myelin recovery in heterozygous jimpy mice: An autoradiographic study

1986 • 14 citations

Cell free synthesis of rat brain myelin proteolipids and their identification by immunoprecipitation

1983 • 13 citations

Proteins from sciatic-nerve myelin in quaking and jimpy mice

1978 • 12 citations

Hypomyelinated mutant mice IV: Peripheral myelin injpmsd

1981 • 11 citations

Detection of wolfgram W1 protein, myelin basic proteins and proteolipids in cultured oligodendrocytes by the electro-immunoblotting method

1983 • 11 citations

Proteolipids

1982 • 11 citations

The quaking mouse: Regional variations in the content and protein composition of myelin isolated from the central nervous system

1979 • 11 citations

Immunochemical evidence of phosphorylation of a new 23K basic protein in rat brain myelin

1986 • 10 citations

Alteration of the primary pattern of central myelin in a chimaeric environment — study of shiverer ↔ wild-type chimaeras

1986 • 10 citations

Developmental expression of myelin basic protein mRNA in a hypermyelinating mouse

1986 • 9 citations

Allelism of two myelin deficiency mutations in the mouse

1981 • 9 citations

Subcellular Distribution and Developmental Expression of Cholesterol Ester Hydrolases in Fetal Rat Brain Cultures

1985 • 8 citations

Characterization of a novel monoclonal anti-myelin basic protein antibody: use in immunoblotting and immunohistochemical studies

1987 • 8 citations

Myelin basic protein‐specific protein methylase I activity in shiverer mutant mouse brain

1986 • 7 citations

Acylation of myelin proteolipid protein in subcellular fractions of rat brainstem

1986 • 4 citations