Masked Messenger RNA and Cytoplasmic DNA in Relation to Protein Synthesis and Processes of Fertilization and Determination in Embryonic Development

The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides

1961 • 1,559 citations

Regulation of Metabolic Processes in Mitochondria

1967 • 1,182 citations

An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis

1961 • 1,108 citations

General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and Differentiation

1961 • 1,043 citations

Sedimentation characteristics of rapidly labelled RNA from HeLa cells

1962 • 1,033 citations

Unstable Ribonucleic Acid Revealed by Pulse Labelling of Escherichia Coli

1961 • 657 citations

HISTONE, A SUPPRESSOR OF CHROMOSOMAL RNA SYNTHESIS

1962 • 590 citations

INHIBITION BY PUROMYCIN OF AMINO ACID INCORPORATION INTO PROTEIN

1959 • 561 citations

RNA synthesis during the development of Xenopus laevis, the South African clawed toad

1964 • 528 citations

ACTION OF ACTINOMYCIN DON ANIMAL CELLS AND VIRUSE

1962 • 498 citations

Electron Microscope Studies of Ribosomal Clusters Synthesizing Hemoglobin

1962 • 424 citations

ON THE ROLE OF HISTONES IN REGULATING RIBONUCLEIC ACID SYNTHESIS IN THE CELL NUCLEUS

1963 • 410 citations

Studien �ber den Eiwei�umsatz der Zelle

1941 • 387 citations

Cell Specificity of Histones

1950 • 363 citations

A rapidly labeled RNA in rat liver nuclei

1962 • 340 citations

Entrance of newly formed messenger RNA and ribosomes into HeLa cell cytoplasm

1965 • 337 citations

Physical and Topological Properties of Circular DNA

1966 • 335 citations

Macromolecule synthesis and the influence of actinomycin on early development

1964 • 298 citations

Deoxyribonucleic acid in amphibian eggs

1965 • 291 citations

Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs

1963 • 280 citations

ENZYMATIC INCORPORATION OF RIBONUCLEOSIDE TRIPHOSPHATES INTO THE INTERPOLYNUCLEOTIDE LINKAGES OF RIBONUCLEIC ACID

1960 • 279 citations

Plastids and Mitochondria: Inheritable Systems

1964 • 259 citations

Oogenesis: The Storage of Developmental Information

1962 • 242 citations

Synthetic processes and early development in the Mammalian egg

1964 • 238 citations

Characterization of RNA synthesized in Escherichia coli after bacteriophage T2 infection

1960 • 233 citations

TEMPLATES FOR THE FIRST PROTEINS OF EMBRYONIC DEVELOPMENT

1964 • 222 citations

Chapter 1 On “Masked” Forms of Messenger Rna in Early Embryogenesis and in Other Differentiating Systems

1966 • 221 citations

The general occurrence of mitochondrial DNA

1965 • 221 citations

THE SELECTIVE SYNTHESIS OF INFORMATIONAL RNA IN BACTERIA

1961 • 218 citations

Chemistry and Physiology of Fertilization

1965 • 217 citations

Messenger RNA in Early Sea-Urchin Embryos: Cytoplasmic Particles

1965 • 209 citations

The American arbacia and other sea urchins

1956 • 207 citations

The Nature of the Intermolecular Forces Operative in Biological Processes

1940 • 205 citations

Protein synthesis in sea urchin eggs: a "late" response to fertilization.

1967 • 191 citations

PROTEIN SYNTHESIS IN ERYTHROID CELLS, I. RETICULOCYTE RIBOSOMES ACTIVE IN STIMULATING AMINO ACID INCORPORATION

1962 • 186 citations

Activation of protein biosynthesis in non-nucleate fragments of sea urchin eggs

1964 • 173 citations

The effects of actinomycin D and puromycin on morphogenesis in amphibian eggs and Acetabularia mediterranea

1964 • 168 citations

Development of Ilyanassa following removal of the D macromere at successive cleavage stages

1962 • 164 citations

The effect of puromycin on protein metabolism and cell division in fertilized sea urchin eggs

1961 • 160 citations

Mitochondrial DNA in Yeast and Some Mammalian Species

1966 • 159 citations

Activation of ribosomes in sea urchin eggs in response to fertilization

1961 • 156 citations

Experimentally induced activation of the ribosomes of the unfertilized sea urchin egg.

1965 • 155 citations

ISOLATION OF A NUCLEAR RNA FRACTION RESEMBLING DNA IN ITS BASE COMPOSITION

1962 • 151 citations

Synthesis of mitochondrial proteins: Demonstration of a transfer of proteins from microsomes into mitochondria

1967 • 149 citations

The circularity of mitochondrial DNA.

1966 • 143 citations

Konstanz, Wechsel und Typus der Determination und Differenzierung in Zellen aus männlichen Genitalanlagen von Drosophila melanogaster nach Dauerkultur in vivo

1966 • 139 citations

The enzymic incorporation of ribonucleotides into polyribonucleotides and the effect of DNA

1960 • 136 citations

Evidence for the mitochondrial origin of frog egg cytoplasmic DNA.

1966 • 132 citations

Cytodifferentiation and Its Controls

1964 • 132 citations

AMOUNT, LOCATION, PRIMING CAPACITY, CIRCULARITY AND OTHER PROPERTIES OF CYTOPLASMIC DNA IN SEA URCHIN EGGS

1967 • 127 citations

Regulation of the initiation of chick embryo hemoglobin synthesis

1965 • 125 citations

Fertilization;: Comparative morphology, biochemistry, and immunology

1967 • 122 citations

Circular mitochondrial DNA

1966 • 122 citations

Effects of Actinomycin D on Morphogenesis

1963 • 121 citations

Incorporation of the adenine ribonucleotide into RNA by cell fractions from E. coli B

1960 • 117 citations

Changing populations of messenger RNA during sea urchin development.

1966 • 117 citations

Synthesis of HÆmoglobin in Relation to the Maturation of Erythroid Cells

1962 • 113 citations

Properties of ribonucleic acid turnover in T2-infected Escherichia coli

1958 • 111 citations

Incorporation of S35-methionine in the cell fractions of sea urchin eggs and embryos

1958 • 105 citations

CONTROL OF SPECIFIC SYNTHESIS IN THE DEVELOPING PANCREAS.

1964 • 105 citations

Amino acid incorporation into proteins of nucleate and anucleate fragments of sea urchin eggs: Effect of parthenogenetic activation

1963 • 104 citations

The effect of actinomycin D on heart and thigh muscle cells grown in vitro

1964 • 103 citations

The Role of Chromosomes in Development

1964 • 103 citations

Activation of RNA synthesis associated with gastrulation.

1966 • 102 citations

Formation of active ribosomal aggregates (polysomes) upon fertilization and development of sea urchin eggs

1963 • 101 citations

Circular DNA filaments from mouse mitochondria.

1966 • 101 citations

MITOCHONDRIAL DNA FROM PROTOZOA

1965 • 98 citations

The Biology and Chemistry of Fertilization

1965 • 97 citations

POLYRIBOSOMES AND PROTEIN SYNTHESIS DURING RETICULOCYTE MATURATION IN VITRO

1963 • 94 citations

A morphological and histochemical investigation of a preimplantation lethal (t¹²) in the house mouse

1956 • 94 citations

Synthesis of ribosomal RNA during sea-urchin development

1967 • 93 citations

[MESSENGER RNA IN EARLY EMBRYOGENESIS].

1964 • 93 citations

Isolation of deoxyribonucleic acid from mitochondria of chick embryo heart and liver.

1965 • 92 citations

Protein Synthesis During Development: Control through Messenger RNA

1964 • 92 citations

CHROMOSOMALLY DIRECTED PROTEIN SYNTHESIS

1963 • 91 citations

Messenger RNA in Early Sea-Urchin Embryos: Size Classes

1965 • 91 citations

The immediacy of genomic control during early development

1964 • 90 citations

EVIDENCE FOR THE COMPLETE DNA-DEPENDENCE OF RNA SYNTHESIS IN ISOLATED THYMUS NUCLEI

1962 • 88 citations

Synthesis of RNA during oogenesis in the sea urchin

1965 • 88 citations

Characteristics of the Utilization of Nucleosides by Embryos of Paracentrotus lividus

1962 • 86 citations

Specificity of the Interactions Between Histones and Deoxyribonucleic Acid

1964 • 85 citations

RIBONUCLEIC ACID METABOLISM FOLLOWING FERTILIZATION IN SEA URCHIN EGGS

1964 • 85 citations

Biochemistry of Heredity: A General Hypothesis

1961 • 84 citations

Base composition of RNA synthesized during cleavage of the sea urchin embryo

1965 • 83 citations

Interrelation of messenger polyribonucleotides and ribosomes in the sea urchin egg during embryonic development

1962 • 83 citations

Comparative study of the localization of incorporated 14C-labeled amino acids and 35SO4 in the sea urchin ovary, egg and embryo

1961 • 83 citations

THE MANIPULATIONS OF MACROMOLECULAR SUBSTANCES DURING FERTILIZATION AND EARLY DEVELOPMENT OF ANIMAL EGGS

1963 • 81 citations

OLD AND NEW RNA IN THE EMBRYOGENESIS OF THE PURPLE SEA URCHIN

1963 • 80 citations

A RIBONUCLEIC ACID FRACTION FROM YEAST RELATED IN COMPOSITION TO DESOXYRIBONUCLEIC ACID

1960 • 79 citations

The nature of messenger RNA in the early stages of sea urchin development.

1966 • 78 citations

Stimulation of phenylalanine incorporation by polyuridylic acid in homogenates of sea urchin eggs

1962 • 77 citations

Translation-level control of protein synthesis during early development

1965 • 76 citations

A change in permeability and uptake of [14C]uridine in response to fertilization in Strongylocentrotus purpuratus eggs

1965 • 76 citations

Persistence in early amphibian embryos of informational RNA's from the lampbrush chromosome stage of oögenesis.

1967 • 76 citations

Incorporation of N15-labeled glycine and alanine into the proteins of developing sea urchin eggs

1952 • 75 citations

The Uptake of Valine and Cytidine by Sea-Urchin Embryos and its Relation to the Cell Surface

1966 • 75 citations

Characterization of RNA species synthesized during early development of sea urchins

1965 • 72 citations

Ribonucleic acid synthesis during sea urchin embryogenesis

1964 • 69 citations

Polyribosomal protein synthesis in fertilized sea urchin eggs: The effect of actinomycin treatment

1964 • 68 citations

Fate of a Synthetic Polynucleotide Directing Cell-Free Protein Synthesis II. Association with Ribosomes

1962 • 68 citations

Biochemical studies of nucleate and anucleate fragments isolated from sea-urchin eggs

1965 • 68 citations

Nucleic Acids of Mitochondria and Chloroplasts

1965 • 67 citations

An estimation of genetic messages in the unfertilized echinoid egg.

1966 • 67 citations

The appearance of stable polysomes during the development of chick down feathers

1964 • 66 citations

Ribonucleic acid metabolism in unfertilized and fertilized sea-urchin eggs

1963 • 65 citations

Evidence for prelocalization of cytoplasmic factors affecting gene activation in early embryogenesis.

1965 • 64 citations

In vitro incorporation of amino acids into proteins stimulated by RNA from unfertilized sea urchin eggs

1964 • 63 citations

Incorporation of C14-l-leucine into protein by cell-free systems from sea urchin embryos at different stages of development

1960 • 62 citations

Nucleic acids in development

1962 • 61 citations

Polypeptide Synthesis in Sea Urchin Embryogenesis: An Examination with Synthetic Polyribonucleotides

1963 • 61 citations

EXTRANUCLEAR HISTONE IN THE AMPHIBIAN OOCYTE

1962 • 60 citations

THE ONTOGENY OF CHICK EMBRYO HEMOGLOBIN

1962 • 59 citations

Developmental studies of the dipteran salivary gland

1964 • 58 citations

The synthesis of ribonucleic acid in sea urchin embryos

1963 • 56 citations

Configuration of Inactive and Active Polysomes of the Developing Down Feather

1965 • 56 citations

The protein metabolism of sea urchin eggs during early development studied by means of 15N-labeled ammonia

1950 • 55 citations

Proteolytic activity in sea urchin gametes

1950 • 55 citations

Biochemical Aspects of Animalization and Vegetalization in the Sea Urchin Embryo

1964 • 55 citations

DEMONSTRATION OF POLYRIBOSOMES AFTER FERTILIZATION OF THE SEA URCHIN EGG

1964 • 51 citations

Action of actinomycin D on exocrine pancreas cell differentiation

1965 • 51 citations

On the mechanism of ribosomal activation in newly fertilized sea urchin eggs

1964 • 51 citations

Nucleic Acid Synthesis in Seedlings

1967 • 50 citations

THE PROTEIN-SYNTHETIC LESION IN UNFERTILIZED EGGS

1967 • 49 citations

Actinomycin D Effects in Frog Embryos: Evidence for Sequential Synthesis of DNA-Dependent RNA

1963 • 48 citations

Electrophoretic examination of soluble proteins synthesized in early sea urchin development

1965 • 47 citations

INFLUENCE OF INDIVIDUAL AMINO ACIDS ON UPTAKE AND INCORPORATION OF VALINE, GLUTAMIC ACID AND ARGININE BY UNFERTILIZED AND FERTILIZED SEA URCHIN EGGS

1966 • 47 citations

The biochemistry of development

1961 • 46 citations

RNA- and protein-synthesizing capacity of isolated oocytes of the sea urchin Lytechinus pictus

1967 • 44 citations

Changes in rate of transfer of potassium across the membrane upon fertilization of eggs of Arbacia punctulata

1959 • 43 citations

Role of a trypsin-like protease in “informosomes” in a trigger mechanism of activation of protein synthesis by fertilization in sea urchin eggs

1966 • 43 citations

Activity of rat-liver enzymes in the transfer of s-RNA-bound amino acids to protein by ribonucleoprotein particles

1960 • 42 citations

INCORPORATION OF AMINO ACIDS INTO PROTEIN BY ARTIFICIALLY ACTIVATED NON-NUCLEATE FRAGMENTS OF SEA URCHIN EGGS

1966 • 42 citations

A Chemical and Physical Characterization of Echinoid RNA during Early Embryogenesis

1966 • 41 citations

The Blood of Chick Embryos: Quantitative Embryology at a Cellular Level

1964 • 41 citations

Control of Synthesis of RNA and Protein in Diapausing and Injured Cecropia Pupae

1964 • 40 citations

HISTONES AND DIFFERENTIATION

1963 • 40 citations

Size of rapidly labelled ribonucleic acids in human amnion cells

1961 • 39 citations

Acquisition of actinomycin D insensitivity during differentiation of pancreas exocrine cells

1964 • 38 citations

The genetic control of sea urchin development: A chromatographic study of protein synthesis in the Arbacia punctulata Embryo

1966 • 37 citations

Chapter 2 The Transcription of Genetic Information in the Spiralian Embryo

1966 • 37 citations

Protein Synthesis in Enucleated Eggs of Rana pipiens

1965 • 37 citations

Studies on the control of enzyme synthesis during the early embryonic development of the sea urchins

1964 • 37 citations

DNA, RNA and Protein Synthesis after Acute, Severe Blood Loss: A Picture of Erythropoiesis at the Combined Morphological and Molecular Levels*

1964 • 36 citations

Agglutination of Sea-Urchin Eggs by Means of a Substance Extracted from the Eggs

1940 • 35 citations

DEVELOPMENTAL GENETICS AND LETHAL FACTORS

1962 • 34 citations

UPTAKE OF RADIOACTIVE GLUCOSE AND AMINO ACIDS AND THEIR UTILIZATION FOR INCORPORATION INTO PROTEINS DURING MATURATION AND FERTILIZATION OF THE EGGS OF ASTERIAS FORBESII AND SPISULA SOLIDISSIMA

1964 • 34 citations

Release of maternal RNA from some particles as a mechanism of activation of protein synthesis by fertilization in sea urchin eggs

1966 • 34 citations

METABOLIC PROPERTIES OF A RIBONUCLEIC ACID FRACTION IN YEAST

1962 • 34 citations

Effets de l'actinomycine D et de la puromycine sur le métabolisme de l'oocyte en croissance Étude autoradiographique

1964 • 33 citations

Vegetalization of sea urchin larvae by chloramphenicol

1963 • 33 citations

The template activity of chromatin

1965 • 32 citations

Some aspects of the relationship of RNA metabolism to development in normal and mutant mouse embryos cultivated in vitro

1963 • 29 citations

Protein synthesis in non-growing yeast. The respiratory adaptation system

1967 • 29 citations

Activation of amino acids during sea urchin development

1963 • 28 citations

Protein Synthesis in Micromeres of the Sea Urchin Egg

1966 • 27 citations

Effets de l'actinomycine sur le développement embryonnaire

1964 • 27 citations

Genetic implications of histone behavior

1963 • 27 citations

Actinomycin D: Specific Inhibitory Effects on the Explanted Chick Embryo

1963 • 27 citations

Animal and vegetal halves of sea urchin larvae subjected to temporary treatment with actinomycin C and mitomycin C

1963 • 26 citations

Ribonuclease-stable polysomes in the egg of Ascaris lumbricoides

1966 • 25 citations

Effects of Histones on Embryonic Development

1964 • 25 citations

The Invivo aggregation of chick embryo ribosomes in response to low temperature

1967 • 23 citations

PROTEIN SYNTHESIS BY UNFERTILIZED EGGS OF SEA URCHINS

1968 • 23 citations

Effects of Actinomycin D on the lens regenerating system

1964 • 23 citations

Teratogenic action of actinomycin D in the embryonic chick

1961 • 22 citations

Evidence for translational level control of protein synthesis in the development of sea urchin eggs

1966 • 22 citations

The respiration and fertilizable life of Arbacia eggs under sterile and non‐sterile conditions

1938 • 21 citations

STUDIES ON KIDNEY TUBULOGENESIS. I. THE EFFECT OF ACTINOMYCIN D ON TUBULOGENESIS IN VITRO.

1964 • 21 citations

Stimulation of protein synthesis in unfertilized sea urchin eggs by prior metabolic inhibition

1967 • 21 citations

UPTAKE OF DEUTERIUM INTO PROTEINS OF FERTILIZED AND UNFERTILIZED ARBACIA EGGS SUSPENDED IN HEAVY WATER

1952 • 21 citations

Quantitative determination of deoxyribonucleic acid in embryos and unfertilized eggs of Rana pipiens

1964 • 20 citations

An exchange between 32P-labeled pyrophosphate and ATP catalyzed by amino acids in unfertilized sea urchin eggs

1957 • 20 citations

Some properties of a rapidly labelled ribonucleic acid species in Sphaerechinus granularis

1966 • 20 citations

Protein synthesis in sea urchin eggs

1967 • 19 citations

Studies on deoxynucleosidic compounds

1960 • 19 citations

Activation of protein synthesis in sea‐urchin eggs upon fertilization in relation to magnesium and potassium ions

1964 • 18 citations

Effect of actinomycin D on the segregation of animal and vegetal potentialities in the sea urchin egg

1965 • 18 citations

Polyribosomes from Houseflies

1967 • 17 citations

Incorporation of labelled amino acids into the proteins of the mitochondria isolated from the unfertilized eggs and developmental stages of Paracentrotus lividus

1960 • 17 citations

RADIOACTIVE LABELING OF RNAs OF SEA URCHIN EGGS DURING OOGENESIS

1967 • 16 citations

Some physical properties of cytoplasmic deoxyribonucleic acid in unfertilized eggs of Arbacia lixula

1965 • 15 citations

The ribonucleic acid of Epanaphe moloneyi Druce

1960 • 14 citations

The Teratogenic Action of the Antibiotic Actinomycin D

2008 • 13 citations

The Effect of Actinomycin D on Primary Embryonic Induction

1964 • 12 citations

Rapidly labelled ribonucleic acid in Xenopus laevis embryonic cells

1965 • 11 citations

Distribution of basic proteins in centrifuged sea urchin eggs

1966 • 7 citations

[Isolation and properties of DNA of sturgeon oocytes].

1965 • 7 citations