From antianginal drugs to myocardial cytoprotective agents

Specific Pharmacology of Calcium in Myocardium, Cardiac Pacemakers, and Vascular Smooth Muscle

1977 • 1,745 citations

Timolol-Induced Reduction in Mortality and Reinfarction in Patients Surviving Acute Myocardial Infarction

1981 • 1,594 citations

Secondary prevention of vascular disease by prolonged antiplatelet treatment

1988 • 962 citations

Mechanism of Action of Calcium-Channel-Blocking Agents

1982 • 692 citations

Effects of glucose and fatty acids on myocardial ischaemia and arrhythmias

1994 • 528 citations

The mechanisms of nitroglycerin action: stenosis vasodilatation as a major component of the drug response.

1981 • 467 citations

Pathophysiology and pathogenesis of stunned myocardium. Depressed Ca2+ activation of contraction as a consequence of reperfusion-induced cellular calcium overload in ferret hearts.

1987 • 424 citations

Ionic basis of ischaemic cardiac injury: insights from cellular studies

1994 • 185 citations

Comparison of trimetazidine with nifedipine in effort angina: A double-blind, crossover study

1990 • 179 citations

Toward the quiescent coronary plaque

1993 • 173 citations

Cytosolic free Ca2+ in single rat heart cells during anoxia and reoxygenation

1987 • 170 citations

Effects of Nitroglycerin on Regional Myocardial Blood Flow in Coronary Artery Disease

1971 • 151 citations

Unrecognized myocardial infarction and hypertension: The Framingham Study

1985 • 149 citations

Effect of trimetazidine on membrane damage induced by oxygen free radicals in human red cells.

1985 • 146 citations

Internal pH, Na+, and Ca2+ regulation by trimetazidine during cardiac cell acidosis

1988 • 124 citations

Myocardial ischemia?Metabolic pathways and implications of increased glycolysis

1990 • 94 citations

High doses of L-carnitine in acute myocardial infarction: metabolic and antiarrhythmic effects

1989 • 86 citations

Pathogenesis of angina pectoris and role of nitrates in relief of myocardial ischemia

1983 • 48 citations

The mechanism of myocyte death in ischaemia

1993 • 38 citations

Haemodynamic and Metabolic Effects of Timolol (Blocadren®) on Ischaemic Myocardium

1983 • 34 citations

Improved myocardial lactate extraction after propranolol in coronary artery disease: effected by peripheral glutamate and free fatty acid metabolism.

1986 • 19 citations

Inhibition of neutrophil accumulation into ischaemic-reperfused myocardium in the rabbit by trimetazidine

1992 • 6 citations