Silica-Induced Apoptosis Mediated via Scavenger Receptor in Human Alveolar Macrophages

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

Occupational lung disorders

1976 • 408 citations

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

1990 • 311 citations

Pathology of the Lung

1980 • 188 citations

Leukotriene B4 production by the human alveolar macrophage: a potential mechanism for amplifying inflammation in the lung.

1984 • 188 citations

Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages.

1986 • 187 citations

Lung macrophage uptake of unopsonized environmental particulates. Role of scavenger-type receptors.

1995 • 169 citations

Cytokines and cytokine network in silicosis and coal workers' pneumoconiosis

1995 • 169 citations

Immunosuppressive activity induced by nitric oxide in culture supernatant of activated rat alveolar macrophages.

1992 • 81 citations

Bleomycin induces apoptosis in human alveolar macrophages

1995 • 63 citations

Induction of interleukin-1 production by ligands binding to the scavenger receptor in human monocytes and the THP-1 cell line.

1991 • 61 citations

Isolation of phenotypically and functionally distinct macrophage subpopulations from human bronchoalveolar lavage

1992 • 58 citations

Phenotypic and functional changes in alveolar macrophages contribute to the pathogenesis of pulmonary sarcoidosis.

1988 • 48 citations