Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Anti-Neutrophil Cytoplasmic Autoantibodies with Specificity for Myeloperoxidase in Patients with Systemic Vasculitis and Idiopathic Necrotizing and Crescentic Glomerulonephritis

1988 • 1,431 citations

Small-Vessel Vasculitis

1997 • 1,308 citations

Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro.

1990 • 1,214 citations

Severe Impairment in Early Host Defense againstCandida albicansin Mice Deficient in Myeloperoxidase

1999 • 304 citations

Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells

1992 • 261 citations

Antibodies Against Granule Proteins Activate Neutrophils In Vitro

1991 • 226 citations

Neutrophil activation in vitro and in vivo in Wegener's granulomatosis

1994 • 204 citations

Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors.

1997 • 178 citations

Interleukin-8: A pathogenetic role in antineutrophil cytoplasmic autoantibody-associated glomerulonephritis

1999 • 143 citations

Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3 [letter; comment]

1990 • 129 citations

IL-1β production by human polymorphonuclear leucocytes stimulated by anti-neutrophil cytoplasmic autoantibodies: relevance to systemic vasculitis

1996 • 116 citations

Animal models of anti-neutrophil cytoplasmic antibody associated vasculitis

1998 • 103 citations

Pathogenesis of the vascular and glomerular damage in ANCA-positive vasculitis

1998 • 94 citations

New findings in pathogenesis of antineutrophil cytoplasm antibody-associated vasculitis

2002 • 81 citations

Neutrophil activation by anti-proteinase 3 antibodies in Wegener's granulomatosis: role of exogenous arachidonic acid and leukotriene B4 generation.

1996 • 73 citations

Reactivity of antineutrophil cytoplasmic autoantibodies with mononuclear phagocytes

1992 • 69 citations

The Effects of Dementia in German Acute Care Hospitals

1997 • 42 citations

Large-Scale Purification of Myeloperoxidase from HL60 Promyelocytic Cells: Characterization and Comparison to Human Neutrophil Myeloperoxidase

2000 • 39 citations