Nelarabine

Acute Lymphoblastic Leukemia

1998 • 816 citations

Phase II Study of Nelarabine (compound 506U78) in Children and Young Adults With Refractory T-Cell Malignancies: A Report From the Children’s Oncology Group

2005 • 300 citations

Phase I Study of 506U78 Administered on a Consecutive 5-Day Schedule in Children and Adults With Refractory Hematologic Malignancies

2005 • 168 citations

Differential Sensitivity of Human Leukemic T Cell Lines and B Cell Lines to Growth Inhibition by Deoxyadenosine

1978 • 167 citations

Compound GW506U78 in refractory hematologic malignancies: relationship between cellular pharmacokinetics and clinical response.

1998 • 110 citations

Selective toxicity of deoxyguanosine and arabinosyl guanine for T- leukemic cells

1983 • 94 citations

Mechanisms for T-cell selective cytotoxicity of arabinosylguanine

2003 • 78 citations

Pharmacokinetics of Nelarabine and 9-Beta-<scp>d</scp>-Arabinofuranosyl Guanine in Pediatric and Adult Patients During a Phase I Study of Nelarabine for the Treatment of Refractory Hematologic Malignancies

2000 • 69 citations

An enzymic synthesis of purine d-Arabinonucleosides

1981 • 62 citations

Evaluation of the Combination of Nelarabine and Fludarabine in Leukemias: Clinical Response, Pharmacokinetics, and Pharmacodynamics in Leukemia Cells

2001 • 58 citations

Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts.

1984 • 47 citations