trans activation of human alcohol dehydrogenase gene expression in hepatoma cells by C/EBP molecules bound in a novel arrangement just 5' and 3' to the TATA box.

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

The DNA Binding Domain of the Rat Liver Nuclear Protein C/EBP Is Bipartite

1989 • 661 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

The interplay of DNA-binding proteins on the promoter of the mouse albumin gene

1987 • 532 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

Developmental changes and polymorphism in human alcohol dehydrogenase

1971 • 375 citations

Sequence-specific interactions of nuclear factors with the insulin gene enhancer

1986 • 309 citations

A liver-specific DNA-binding protein recognizes multiple nucleotide sites in regulatory regions of transthyretin, alpha 1-antitrypsin, albumin, and simian virus 40 genes.

1988 • 239 citations

Development of Alcohol Dehydrogenase Activity in the Human Liver

1967 • 198 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification, Genetic Specificity, and TATA Box-Promoter Interactions of TFIID

1988 • 184 citations

Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B

1990 • 148 citations

Characterization of human alcohol dehydrogenase isoenzymes by high-performance liquid chromatographic peptide mapping

1982 • 73 citations

Transcription Initiation from the Dihydrofolate Reductase Promoter Is Positioned by HIP1 Binding at the Initiation Site

1990 • 72 citations

Multiple mRNAs for human alcohol dehydrogenase (ADH): developmental and tissue specific differences

1986 • 41 citations

Factor Substitution in a Human HSP70 Gene Promoter: TATA-Dependent and TATA-Independent Interactions

1990 • 29 citations