Enzymological Aspects of Steroid Conjugation
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Abstract
References (186)
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue
1955 • 4,109 citations
The kinetics of enzyme-catalyzed reactions with two or more substrates or products
1963 • 1,885 citations
Studies on glucosaminidase. 4. The fluorimetric assay of N-acetyl-β-glucosaminidase
1961 • 458 citations
APPLICATION OF AN IMPROVED GLUCURONIDASE ASSAY METHOD TO THE STUDY OF HUMAN BLOOD β-GLUCURONIDASE
1948 • 428 citations
Mammalian glycosidases. Distribution in the body
1959 • 354 citations
ENZYMATIC FORMATION OF URIDINE DIPHOSPHOGLUCURONIC ACID
1957 • 351 citations
The preparation and properties of β-glucuronidase. 4. Inhibition by sugar acids and their lactones
1952 • 320 citations
Enzymatic Reactions Involving Sulfate, Sulfite, Selenate, and Molybdate
1958 • 317 citations
Biological Sulfate Activation and Transfer
1958 • 273 citations
Inhibition of glycosidases by aldonolactones of corresponding configuration. 2. Inhibitors of β-N-acetylglucosaminidase
1958 • 251 citations
The Solubilization and Partial Purification of a Glucuronyl Transferase from Rabbit Liver Microsomes
1962 • 235 citations
Inhibition of glycosidases by aldonolactones of corresponding configuration
1957 • 224 citations
Studies on glucosaminidase. 3. Testicular N-acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase
1961 • 223 citations
Glycogen metabolism in embryonic chick and neonatal rat liver
1963 • 217 citations
ISOLATION AND IDENTIFICATION OF ACTIVE SULFATE
1957 • 212 citations
Enzymatic Synthesis of Adenosine-5′-Phosphosulfate
1958 • 203 citations
Separation and properties of β-galactosidase, β-glucosidase, β-glucuronidase and N-acetyl-β-glucosaminidase from rat kidney
1967 • 192 citations
The synthesis of bilirubin glucuronide in animal and human liver
1958 • 190 citations
Comparative studies on the liver sulphatases
1958 • 189 citations
Uridine compounds in glucuronic acid metabolism. 1. The formation of glucuronides in liver suspensions
1954 • 187 citations
The formation of bile acid sulfates: a new pathway of bile acid metabolism in humans.
1967 • 185 citations
Separation of the Two Enzymatic Phases in Active Sulfate Synthesis
1958 • 184 citations
Uridyl Transferases and the Formation of Uridine Triphosphate: Enzymic Production of Uridine Triphosphate: Uridine Diphosphoglucose Pyrophosphorolysis
1953 • 182 citations
ENZYMATIC SYNTHESIS OF STEROID SULFATES
1956 • 174 citations
Metabolism of <scp>d</scp>-glucuronolactone in mammalian systems. Identification of <scp>d</scp>-glucaric acid as a normal constituent of urine
1963 • 169 citations
The steroid sulphatase of Patella vulgata
1956 • 165 citations
Separation of Steroid Sulfokinases
1958 • 164 citations
Inhibition of UDP-D-glucose dehydrogenase by UDP-D-xylose: A possible regulatory mechanism
1965 • 148 citations
The Biosynthesis of Glucuronides
1966 • 146 citations
Glucuronide synthesis in foetal liver and other tissues
1959 • 136 citations
Studies on glucosaminidase. N-Acetyl-β-glucosaminidase in rat kidney
1957 • 130 citations
Uridine nucleotide compounds of liver
1954 • 124 citations
Purification of β-N-acetylglucosaminidase from the pig epididymis
1960 • 121 citations
Studies on sulphatases. 12. The arylsulphatases of human tissues
1956 • 117 citations
Uridine diphosphoglucose dehydrogenase of pea seedlings
1957 • 115 citations
The enzymic conversion of glucosamine to galactosamine
1959 • 115 citations
Investigations of the Properties and Mechanism of the Uridine Diphosphate Glucose Pyrophosphorylase Reaction.
1955 • 109 citations
Determination of Mammalian Steroid Sulfatase with 7 α-H3-3 β-Hydroxyandrost-5-en-17-one Sulfate
1963 • 105 citations
Studies on glucosaminidase. 2. Substrates for N-acetyl-β-glucosaminidase
1961 • 103 citations
Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ‘ester’, aliphatic and steroid glucuronides
1956 • 102 citations
Nucleotides Involved in the Enzymatic Conjugation of Phenols with Sulfate
1958 • 98 citations
Glucuronide synthesis in kidney and gastrointestinal tract
1962 • 95 citations
The inhibition of β-glucuronidase by saccharic acid and the role of the enzyme in glucuronide synthesis
1949 • 95 citations
The Sulfatase of Ox Liver. IX. The Polymerization of Sulfatase A*
1965 • 93 citations
Mammalian α-Acetylglucosaminidase. Enzymic Properties, Tissue Distribution, and Intracellular Localization*
1967 • 92 citations
Mammalian glycosidases. 4. The intracellular localization of β-galactosidase, α-mannosidase, β-N-acetylglucosaminidase and α-<scp>l</scp>-fucosidase in mammalian tissues
1963 • 91 citations
Assay of Sulfatases
1957 • 87 citations
STUDIES ON THERMOPHILIC SULFATE-REDUCING BACTERIA III
1962 • 87 citations
The Suiphatase of Ox Liver*
1964 • 87 citations
Oligosaccharase Activity of β-N-Acetyl-d-glucosaminidase of Beef Liver
1964 • 86 citations
Purification of β-glucuronidase from the preputial gland of the female rat
1958 • 85 citations
Distribution of Steroid Sulfatase in Human Tissues
1965 • 84 citations
ENZYMIC CATALYSIS OF GLUCURONYL TRANSFER
1957 • 83 citations
Uridine Diphosphoacetylglucosamine Pyrophosphorylase
1959 • 80 citations
INFLUENCE OF GONADECTOMY, SEX HORMONES AND OTHER FACTORS, ON THE ACTIVITY OF CERTAIN GLYCOSIDASES IN THE RAT AND MOUSE
1959 • 79 citations
PURIFICATION OF URIDINEDIPHOSPHATE GLUCOSE PYROPHOSPHORYLASE FROM MUNG BEAN SEEDLINGS
1958 • 76 citations
Purification and Properties of Human Liver β-Glucuronidase
1965 • 76 citations
Some Stereospecificity Studies with Tritiated Pyridine Nucleotides*
1963 • 74 citations
The Synthesis of α-D-Glucosamine-1-phosphate and N-Acetyl-α-D-glucosamine-1-phosphate. Enzymatic Formation of Uridine Diphosphoglucosamine1
1956 • 74 citations
The sulphatase of ox liver. 6. Steroid sulphatase
1957 • 71 citations
The enzymic synthesis of steroid sulphates
1956 • 70 citations
β-Glucuronidase and the Hydrolysis of Glucuronides
1966 • 67 citations
Studies on β-glucuronidase. 2. The preparation and properties of three ox-spleen β-glucuronidase fractions
1953 • 66 citations
Purification and characterization of bovine liver β-glucuronidase
1966 • 66 citations
Studies on -Glucuronidase from E. coli.
1951 • 62 citations
Uridine diphosphoglucose pyrophosphorylase of pea seeds
1958 • 62 citations
Studies on glucosaminidase. 6. N-Acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase activities of a variety of enzyme preparations
1961 • 61 citations
Some properties of uridine diphosphoglucose dehydrogenase
1956 • 61 citations
Synthesis of Adenylyl Sulfate and Adenylyl Sulfate 3'-Phosphate
1964 • 60 citations
Studies on glucosaminidase. 5. Kidney N-acetyl-β-glucosaminidase and N-acetyl-β-galactosaminidase
1961 • 60 citations
The sulphatase of ox liver. XI. The isoelectric focussing of a purified preparation of sulphatase B
1968 • 60 citations
Properties of steroid sulphatase and arylsulphatase activities of human placenta
1967 • 59 citations
The biosynthesis of labeled estriol-3-sulfate-16-glucosiduronate
1965 • 59 citations
Vitamin A and the sulfate-activating enzymes
1966 • 59 citations
Ethereal and N-linked glucuronide formation by normal and Gunn rats in vitro and in vivo
1961 • 57 citations
Enzymic formation of oestrone 3-glucuronide by rabbit-liver microsomes
1963 • 57 citations
Studies on Phenolic Steroids in Human Subjects: VI. Biosynthesis of Estriolglucosiduronic Acid-16-14C by Human Liver1
1964 • 56 citations
The Isolation from Rabbit Urine of a Conjugate of 17α-Estradiol with N-Acetylglucosamine
1964 • 56 citations
The use of phenol glucuronide in the assay of β-glucuronidase
1948 • 55 citations
5-Pregnene-3β,20α-diol-3-sulfate-20- (2'-acetamido-2'-deoxy-α-D-glucoside) and 5-Pregnene-3β,20α-diol-3,20-disulfate. Two Novel Urinary Conjugates*
1967 • 54 citations
Observations on the biosynthesis of thiamine in yeast
1966 • 54 citations
Kinetic studies of the phenol sulphotransferase reaction
1968 • 54 citations
The preparation and properties of β-glucuronidase. 6. Activity in rat-liver preparations
1953 • 54 citations
The activation of an arylsulphatase from ox liver by chloride and other anions
1959 • 53 citations
The Comparative Ability of β-Glucuronidase Preparations (Liver, Escherichia coli, Helix pomatia, and Patella vulgata) to Hydrolyze Certain Steroid Glucosiduronic Acids
1961 • 53 citations
Dehydroepiandrosterone Sulfate: A Secretory Product of the Boar Testis
1967 • 53 citations
The relationship between glucuronidase and galacturonidase activity in the limpet and in mammalian tissues
1958 • 51 citations
β-GLUCURONIDASE
1953 • 50 citations
Dissociation and Activation of β-Glucuronidase1
1954 • 50 citations
D-Glucopyranosiduronates. I. Steroidyl-β-D-glucopyranuronosides1,2
1959 • 49 citations
Studies on ester sulfates
1959 • 49 citations
Uridine Diphosphate Glucose Dehydrogenase
1963 • 48 citations
The hydrolysis of glucosaminides by an enzyme in Helix pomatia
1939 • 47 citations
Biosynthesis of steroid sulfates by normal human testis
1965 • 46 citations
DISTRIBUTION OF SOME STEROID SULPHOKINASES IN FOETAL HUMAN TISSUES
1966 • 46 citations
α-GLUCOSAMINIDASE
1951 • 46 citations
SOME DIFFERENCES IN THE CONJUGATION OF O-AMINOPHENOL AND P-NITROPHENOL BY THE URIDINE DIPHOSPHATE TRANSGLUCURONYLASE OF MOUSE-LIVER HOMOGENATES
1965 • 45 citations
mesoInositol in the lens of mammalian eyes
1957 • 44 citations
Identification in Rabbit Urine of the 3-Glucuronoside-17-N-acetylglucosaminide of 17α-Estradiol
1965 • 44 citations
The sulphatase of ox liver. 5. Sulphatase C
1956 • 43 citations
Function of vitamin a in the synthesis of 3′-phosphoadenosine-5′-phosphosulfate
1960 • 42 citations
Über Oestronsulfat, ein physiologisches Ausscheidungsprodukt des Follikelhormons
1939 • 41 citations
[31] Glucuronidases
1955 • 41 citations
Studies on β-glucuronidase. 4. The purification and properties of ox-liver β-glucuronidase
1953 • 41 citations
Purification of β-acetylglucosaminase and β-galactosidase from ram testis
1966 • 40 citations
Steroids of Invertebrates: Production of Oestrogens by an Accessory Reproductive Tissue of the Slug Arion ater rufus (Linn.)
1967 • 40 citations
The activation of sulphate by extracts of cornea and colonic mucosa from normal and vitamin A-deficient animals
1963 • 40 citations
Biosynthesis of Steroid Sulfates by Human Ovarian Tissue
1964 • 39 citations
The uridyl transferase of liver
1954 • 37 citations
The isolation of urinary 17-oxo steroid and corticosteroid glucuronides
1964 • 36 citations
Enzymic synthesis of steroid sulphates I. Sulphation of steroids by human adrenal extracts
1964 • 36 citations
Steroid sulphatase, arylsulphatase and β-glucuronidase in marine invertebrates
1960 • 36 citations
Steroid sulphatase, arylsulphatase and β-glucuronidase in the mollusca
1960 • 35 citations
Sulfur Metabolism of Aerobactor aerogenes II. The Purification and Some Properties of a Sulfatase
1964 • 35 citations
Studies on metabolism of vitamin A. 6. The effect of vitamin A deficiency on the activation of sulphate and its transfer to p-nitrophenol in rat liver
1964 • 34 citations
A method for the estimation of dehydroepiandrosterone in urine
1959 • 34 citations
Steroids of Invertebrates: the in vitro Production of II-Ketotestosterone and Other Steroids by the Eggs of the Slug, Arion ater rufus (Linn.)
1966 • 34 citations
Properties of limpet β-glucuronidase
1957 • 32 citations
Enzymatic sulfation of steroids by bovine tissues
1965 • 32 citations
The formation of cholesteryl sulphate by androstenolone sulphotransferase
1967 • 31 citations
Studies on Ester Sulphates. 14. The in vitro Formation of Steroid Disulphates in Rat Liver Extracts.
1963 • 31 citations
“Activator-competitive” enzyme inhibition. Interrelation of dissociation, activation, inhibition and surface inactivation of β-glucuronidase
1957 • 31 citations
Über Emulsin. XIII. Darstellung und fermentative Spaltung von Glykosiden des N-Acetyl-glucosamins und der 2-Desoxyglucose.
1933 • 31 citations
343. Synthesis of “active sulphate”(adenosine 3′-phosphate 5′-sulphatophosphate)
1959 • 31 citations
Contribution to the study of the structure of the aldosterone-conjugate isolated from human urine
1965 • 31 citations
An electrophoretic investigation of interactions between bovine plasma albumin and charged dextran derivatives
1961 • 30 citations
Glycosulphatase: observations on the activity of partially purified preparations towards the sulphate esters of certain monosaccharides and steroids
1961 • 30 citations
Eine Steroidsulfatase aus Säugetierleber
1956 • 29 citations
The uridyl transferase of mammary gland
1955 • 29 citations
STUDIES ON ESTER SULPHATES
1967 • 29 citations
The mechanism of glucuronide formation
1961 • 28 citations
Comparison of Different Glycosidase Activities in Conditions of Cancer
1957 • 28 citations
The cerimetric determination of glucuronic acid, using the Conway burette
1946 • 28 citations
Formation of UDPGla and Related Compounds by the Soluble Fraction of Liver
1956 • 27 citations
Occurrence of a mammalian α-N-acetyl-d-galactosaminidase
1966 • 27 citations
Action of β-glucuronidase on a steroid-enol-β-glucosiduronic acid
1961 • 26 citations
Enzymic synthesis of steroid sulphates
1967 • 25 citations
Ox spleen β-glucuronidase; its purification and a study of some factors involved in assaying its activity
1946 • 25 citations
The Formation of Estradiol-3-glucuronoside-17α-N-acetylglucosaminide by Rabbit Liver Homogenate*
1965 • 25 citations
Biosynthese von Steroidglucuroniclen durch Rattenlebermikrosomen. Zur Frage des Verhaltens der UDP-Glucuronyl-Transferase-Aktivität unter Nahrungsentzug und im Alloxandiabetes
1966 • 24 citations
The enzymic hydrolysis of steroid conjugates. 1. Sulphatase and β-glucuronidase activity of molluscan extracts
1956 • 24 citations
IN VITROSYNTHESIS OF DEHYDROEPIANDROSTERONE SULFATE1
1955 • 24 citations
HYDROLYSIS OF CONJUGATED SULFATES OF ESTROGENS BY COMMERCIAL ENZYME PREPARATION OF ASPERGILLUS ORYZAE
1949 • 23 citations
Sulfate metabolism in avion and mammalian cartilage extracts
1963 • 22 citations
THE ARYLSULPHATASES AND RELATED ENZYMES IN THE LIVERS OF SOME LOWER VERTEBRATES
1963 • 22 citations
Sulphate Conjugation during Development, in Human, Rat and Guinea Pig
1966 • 21 citations
The synthesis of 3′-phosphoadenosine 5′-phosphosulfate by retinae and livers of normal and vitamin A-deficient rats
1966 • 21 citations
Paradoxical Action of Solvents on Bacterial and Liver β-Glucuronidases
1959 • 20 citations
STUDIES ON ESTER SULPHATES
1964 • 20 citations
ON β-GLUCURONOSIDASE
1936 • 20 citations
Inhibition of β-Glucuronidase by Cholesterol and Retinol
1967 • 20 citations
Steroid glucuronides I. The synthesis of β-d-glucopyranosiduronic acids of 3-hydroxy-androstane-17-ketones
1965 • 19 citations
Action of Copper on Mammalian β-Glucuronidase
1957 • 18 citations
Charakterisierung und Kinetik einer mikrosomalen UDP-Glucuronat: Testosteron-Glucuronyltransferase beim Menschen
1966 • 18 citations
Über Steroid-Konjugate in Plasma, XIII. Isolierung, Eigenschaften und Zusammensetzung eines biosynthetischen, lipophilen Dehydroepiandrosteron-Konjugats
1965 • 17 citations
The extraction and hydrolysis of steroid monoglucuronides
1966 • 17 citations
A glucuronic-decomposing enzyme from rumen micro-organisms. 3. Mode of action, specificity and inhibition by acidic sugar derivatives
1955 • 17 citations
Possible allosteric effects with arylamine sulphokinase
1964 • 16 citations
Die Verbreitung der Aryl- und Steroidsulfatasen
1959 • 16 citations
DEHYDROEPIANDROSTERONE IN BLOOD
1958 • 16 citations
Studies on metabolism of vitamin A. The effect of the stage of vitamin A deficiency on sulphate activation in rat liver
1966 • 16 citations
The enzymic synthesis of aryl sulphamates. 2. The effect of 3β-methoxyandrost-5-en-17-one on arylamine sulphokinase
1961 • 15 citations
Enzymatische Bildung von Östradiol-(17β)-glucuroniden in der Mikrosomen-Fraktion der Kaninchenleber
1966 • 15 citations
Partial purification of a soluble UDPglucuronyltransferase from human intestine
1966 • 15 citations
Duodenal Glucuronide Synthesis. II. Identification of Estradiol Glucuronide as a Conjugation Product of Estradiol by Rat Duodenal Mucosa. Qualitative Studies.
1958 • 15 citations
Metabolism of Drugs. XLV. Synthesis of 2-Naphthyl β-D-Glucofuranosiduronic Acid.
1964 • 15 citations
Zur Bildung wasserlöslicher Metaboliten aus Oestron in Rattenlebermikrosomen
1965 • 14 citations
BIOGENESE VON ÖSTRIOL-16α-MONOGLUCURONID UND ÖSTRIOL-17β-MONOGLUCURONID
1966 • 14 citations
METABOLIC ACTIVITIES OF VITAMIN D IN ANIMALS
1965 • 14 citations
PURIFICATION OF URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE FROM HUMAN BRAIN*
1961 • 14 citations
Reinigung und charakterisierung einer löslichen uridin diphosphat-glucuronat: 17β-hydroxysteroid-glucuronyl-transferase beim menschen
1966 • 14 citations
Metabolism of Drugs. XLIV. Glucuronyl Transfer Reaction catalyzed by β-Glucuronidase by the Use of Ester Glucuronides as Substrates.
1964 • 13 citations
Crystalline beta-Glucuronidase.
1964 • 12 citations
Metabolism of Drugs. XLVI. Behavior of 2-Naphthyl β-D-Glucofuranosiduronic Acid toward β-Glucuronidase.
1964 • 12 citations
Glucuronic Conjugation of Steroids in the Avian Adrenal Gland.
1960 • 12 citations
Mammalian Liver β-Glucuronidase for Hydrolysis of Steroidal Conjugates
1960 • 12 citations
Some Properties of the Uridine Diphosphate Glucose Pyrophosphorylase.
1957 • 12 citations
BIOCHEMICAL STUDIES ON CARBOHYDRATES
1936 • 11 citations
3α-Ureido-11β-hydroxy-Δ4-androsten-17-one, a Novel Steroid Transformation in Man
1966 • 11 citations
Studies on a Liver Activator of β-Glucuronidase
1961 • 11 citations
Steroid glucuronides II. The hydrolysis of β-d-glucosiduronic acids by β-glucuronidases
1965 • 10 citations
Purification and properties of β-N-acetylglucosaminidase from bovine uterus
1967 • 10 citations
The enzymic synthesis of aryl sulphamates. 3. The specificity and mechanism of the activation of rat-Liver arylamine sulphokinase by 17-oxo steroids
1962 • 9 citations
Preparation of Substrates for Assay of Sulphotransferases
1962 • 7 citations
Isolation, Characterization, and Synthesis of 3α-Ureido-11β-hydroxy-Δ4-androsten-17-one
1966 • 6 citations
Steroidsulfatase in the Liver of Charonia lampas
1961 • 2 citations