Immunohistochemistry

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETES

1970 • 5,141 citations

A Flexible System of Enzymatic Analysis

1972 • 4,133 citations

Coupling of enzymes to proteins with glutaraldehyde

1969 • 1,442 citations

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

1973 • 1,057 citations

NONDROPLET ULTRASTRUCTURAL DEMONSTRATION OF CYTOCHROME OXIDASE ACTIVITY WITH A POLYMERIZING OSMIOPHILIC REAGENT, DIAMINOBENZIDINE (DAB)

1968 • 892 citations

Fluorescence Microscopy: Reduced Photobleaching of Rhodamine and Fluorescein Protein Conjugates by n -Propyl Gallate

1982 • 851 citations

Fading of immunofluorescence during microscopy: a study of the phenomenon and its remedy

1982 • 822 citations

Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry.

1982 • 659 citations

SIMULTANEOUS LOCALIZATION OF MULTIPLE TISSUE ANTIGENS USING THE PEROXIDASE-LABELED ANTIBODY METHOD: A STUDY ON PITUITARY GLANDS OF THE RAT

1968 • 651 citations

The Demonstration of Pneumococcal Antigen in Tissues by the Use of Fluorescent Antibody

1942 • 621 citations

ENZYME-LABELED ANTIBODIES FOR THE LIGHT AND ELECTRON MICROSCOPIC LOCALIZATION OF TISSUE ANTIGENS

1967 • 614 citations

CYTOCHEMICAL DEMONSTRATION OF PEROXIDASE ACTIVITY WITH 3-AMINO-9-ETHYLCARBAZOLE

1965 • 552 citations

Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems.

1981 • 545 citations

Retardation of fading and enhancement of intensity of immunofluorescence by p-phenylenediamine.

1983 • 544 citations

Fluorescent Antibody Methods

1968 • 436 citations

INHIBITION OF ERYTHROCYTE PSEUDOPEROXIDASE ACTIVITY BY TREATMENT WITH HYDROGEN PEROXIDE FOLLOWING METHANOL

1972 • 370 citations

Principles of Biological Microtechnique

1959 • 330 citations

The unlabeled antibody method. Contrasting color staining of paired pituitary hormones without antibody removal.

1979 • 315 citations

The use of proteolytic enzymes to improve immunoglobulin staining by the PAP technique

1979 • 309 citations

Immunoperoxidase technique in histopathology: applications, methods, and controls.

1979 • 282 citations

An integrating microdensitometer for biological cells

1955 • 277 citations

Immunoperoxidase Technics in Diagnostic Pathology: Report of a Workshop Sponsored by the National Cancer Institute

1979 • 265 citations

Background staining and sensitivity of the unlabelled antibody-enzyme (PAP) method. Comparison with the peroxidase labelled antibody sandwich method using formalin fixed paraffin embedded material

1975 • 247 citations

Bifunctional reagents as vapour- and liquid-phase fixatives for immunohistochemistry

1975 • 246 citations

High-grade intensification of the end-product of the diaminobenzidine reaction for peroxidase histochemistry.

1982 • 226 citations

The unmasking of antigens in paraffin sections of tissue by trypsin

1977 • 216 citations

Standardization in Immunofluorescence

1970 • 195 citations

[55] The avidin-biotin complex in affinity cytochemistry

1979 • 194 citations

Pancreatic islet cell hormones distribution of cell types in the islet and evidence for the presence of somatostatin and gastrin within the D cell.

1976 • 187 citations

Melanoproteins I. reactions between enzyme-generated quinones and amino acids

1965 • 170 citations

Characterization of epithelial elements in human major salivary glands by functional markers: localization of amylase, lactoferrin, lysozyme, secretory component, and secretory immunoglobulins by paired immunofluorescence staining.

1982 • 167 citations

Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P₄₅₀, compared with three further P₄₅₀-isoenzymes, NADPH P₄₅₀-reductase, glutathione transferases and microsomal epoxide hydrolase

1984 • 152 citations

An immunohistochemical study on the localization and distributions of phenobarbital- and 3-methylcholanthrene-inducible cytochromes P-450 within the livers of untreated rats.

1981 • 150 citations

Handbook of immunoperoxidase staining methods

1933 • 143 citations

Immunohistochemical localization of glutathione S-transferases in livers of untreated rats.

1982 • 131 citations

Covalent attachment of proteins to polysaccharide carriers by means of benzoquinone

1975 • 122 citations

A modification of the unlabeled antibody enzyme method using heterologous antisera for the light microscopic and ultrastructural localization of insulin, glucagon and growth hormone.

1975 • 121 citations

Immunohistochemical analysis of formaldehyde-and trypsin- or pepsin-treated material

1978 • 119 citations

INHIBITION OF PEROXIDASE BY METHANOL AND BY METHANOL-NITROFERRICYANIDE FOR USE IN IMMUNOPEROXIDASE PROCEDURES

1971 • 106 citations

Pronase pretreatment of tissue sections enhances sensitivity of the unlabelled antibody-enzyme (PAP) technique

1977 • 103 citations

Biochemical Mechanisms of Liver Injury.

1979 • 103 citations

Immunohistochemical localizations of cytochromes P-450 in rat liver

1978 • 101 citations

Enhancement of Specific Immunofluorescent Finding with Use of a Para-Phenylenediamine Mounting Buffer

1982 • 88 citations

The labeled antigen method of immunoenzymatic staining.

1979 • 86 citations

Effects of 3-methylcholanthrene, beta-naphthoflavone, and phenobarbital on the 3-methylcholanthrene-inducible isozyme of cytochrome P-450 within centrilobular, midzonal, and periportal hepatocytes.

1982 • 78 citations

PHENYLHYDRAZINE AS INHIBITOR OF HORSERADISH PEROXIDASE FOR USE IN IMMUNOPEROXIDASE PROCEDURES

1972 • 68 citations

An unlabeled antibody method using glucose oxidase-antiglucose oxidase complexes (GAG): a sensitive alternative to immunoperoxidase for the detection of tissue antigens.

1982 • 66 citations

The reaction of benzoquinone with amines and proteins

1969 • 66 citations

Fluorescent Protein Tracing

1977 • 60 citations

A New Fluorescent Antibody Method: Mixed Antiglobulin Immunofluorescence or Labelled Antigen Indirect Immunofluorescence Staining

1965 • 58 citations

Simultaneous visualization of two antigens in the same tissue section by combining immunoperoxidase with immunofluorescence techniques.

1979 • 51 citations

Simultaneous visualization by light microscopy of two pituitary hormones in a single tissue section using a combination of indirect immunohistochemical methods.

1976 • 51 citations

Comparison of paired immunofluorescence and paired immunoenzyme staining methods based on primary antisera from the same species.

1982 • 50 citations

Optical errors in scanning stage absorbance cytophotometry. I. Procedures for correcting apparent integrated absorbance values for distributional, glare, and diffraction errors.

1980 • 49 citations

Quantitation in histochemistry: A review of some commercially available microdensitometers

1975 • 48 citations

Quantitative histochemistry of biogenic amines

1970 • 45 citations

Detection of Two Antibodies in Single Plasma Cells by the Paired Fluorescence Technique

1965 • 41 citations

USE OF A WATER SOLUBLE CARBODIIMIDE AS A FIXING REAGENT

1977 • 39 citations

Double labeled-antigen method for demonstration of intracellular antigens in paraffin-embedded tissues.

1982 • 38 citations

Manual of immunoperoxidase techniques

1983 • 37 citations

Versatility of Staphylococcus aureus protein A in immunocytochemistry. Use in unlabeled antibody enzyme system and fluorescent methods.

1979 • 33 citations

Optical errors in scanning stage absorbance cytophotometry. II. Application of correction factors for residual distributional error, glare and diffraction error in practical cytophotometry.

1980 • 32 citations

Immunochemical localization of epoxide hydratase in rat liver: Effects of 2-acetylaminofluorene

1979 • 31 citations

Some recent developments in immunocytochemistry

1983 • 30 citations

Immunohistochemical localization of NADPH-cytochrome reductase in rat liver

1978 • 29 citations

CONTRASTING FLUORESCENT LABELS FOR TWO ANTIBODIES

1957 • 27 citations

Immunoperoxidase techniques in human renal biopsy

1982 • 26 citations

Tissue fixation with diimidoesters as an alternative to aldehydes. II. Cytochemical and biochemical studies of rat liver fixed with dimethylsuberimidate.

1976 • 26 citations

Distributions of monooxygenase components and epoxide hydratase within the livers of untreated male rats

1980 • 26 citations

Clinical applications of the enzyme labeled antibody method. Immunoperoxidase methods in diagnostic histopathology.

1979 • 26 citations

The Cytochemical Approach to Hormone Assay

1978 • 24 citations

Quantitative immunohistochemistry: a comparison of microdensitometric analysis of unlabeled antibody peroxidase-antiperoxidase staining and of microfluorometric analysis of indirect fluorescent antibody staining for nicotinamide adenosine dinucleotide phosphate (NADPH)-cytochrome c (P-450) reductase in rat liver.

1983 • 24 citations

THE EFFECT OF HYDROGEN ION CONCENTRATION ON FLUORESCENT LABELLED ANTIBODIES

1964 • 23 citations

Sensitivity and nonspecific staining of various immunoperoxidase techniques

1980 • 23 citations

Amino Acid Incorporation and Biotin Deficiency

1963 • 23 citations

Unlabeled antibody peroxidase-antiperoxidase method combined with direct immunofluorescence.

1981 • 21 citations

Effects of phenobarbital, trans-stilbene oxide, and 3-methylcholanthrene on epoxide hydrolase within centrilobular, midzonal, and periportal regions of rat liver.

1983 • 20 citations

Immunohistochemical localization of adrenal ferredoxin and distribution of adrenal ferredoxin and cytochrome P-450 in the rat adrenal

1978 • 17 citations

Immunofluorescence technology. Selected theoretical and clinical aspects

1983 • 16 citations

Effect of protease pretreatment on immunomorphologic demonstration of hepatitis-B-surface antigen in conventional paraffin-embedded liver biopsy material: Quantitative evaluation

1979 • 16 citations

Immunohistochemical localization of epoxide hydratase in rat liver

1980 • 16 citations

Localization of epoxide-metablozing enzymes in rat testis

1984 • 14 citations

Immunohistochemical studies on electron transport proteins associated with cythochromes P-450 in steroidogenic tissues II. Microsomal NADPH-cytochrome c reductase in the rat adrenal

1979 • 13 citations

Immunohistochemical localization of adrenal ferredoxin in bovine adrenal cortex

1977 • 12 citations

Practical applications of the microphotometric quantification of histoenzyme reactions

1981 • 11 citations

Immunofluorescent Staining of Epon Embedded Kidney Sections Through Simultaneous use of Two Different Fluorochrome-Conjugated Antisera

1982 • 9 citations

Immunohistochemical demonstration of an adrenal ferredoxin-like iron-sulfur protein in rat hepatic mitochondria.

1978 • 9 citations

On the nature of protein benzoquinone complexes

1976 • 7 citations

Investigations of fading of immunofluorescence objects

1982 • 7 citations

Formation de complexes entre la et l'imidazole et ses dérivés

1968 • 5 citations

Immunohistochemical staining using coupled immunofluorescence and immunocomplex technique

1977 • 1 citations

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