Joint Committee for Stroke Facilities

Energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers

1968 • 2,371 citations

Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain

1964 • 2,227 citations

The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

1967 • 1,821 citations

THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN 1

1948 • 1,810 citations

On the Regulation of the Blood‐supply of the Brain

1890 • 1,743 citations

Cerebral ischemia. II. The no-reflow phenomenon.

1968 • 1,346 citations

MULTI-INFARCT DEMENTIA A CAUSE OF MENTAL DETERIORATION IN THE ELDERLY

1974 • 1,079 citations

Reversal of Blood Flow through the Vertebral Artery and Its Effect on Cerebral Circulation

1961 • 573 citations

Effects of Changes in Brain Metabolism on the Levels of Citric Acid Cycle Intermediates

1966 • 396 citations

Adrenergic innervation of pial arteries related to the circle of Willis in the cat

1967 • 383 citations

CEREBRAL VASODILATOR NERVES AND THEIR PATHWAY FROM THE MEDULLA OBLONGATA

1932 • 336 citations

Cerebral ischemia. III. Vascular changes.

1968 • 336 citations

Regional Blood Flow in the Cerebral Cortex, Measured Simultaneously by Heat and Inert Gas Clearance

1966 • 321 citations

Cerebral Hemodynamics during Cerebral Ischemia Induced by Acute Hypotension1

1954 • 298 citations

Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia

1974 • 293 citations

Use of radioactive microspheres to assess distribution of cardiac output in rabbits

1968 • 286 citations

INNERVATION OF INTRACRANIAL ARTERIES

1970 • 263 citations

Dual Adrenergic and Cholinergic Innervation of the Cerebral Arteries of the Rat

1970 • 256 citations

Relation between EEG, regional cerebral blood flow and internal carotid artery pressure during carotid endarterectomy

1973 • 252 citations

Restoration of Middle Cerebral Artery Flow in Experimental Infarction

1969 • 212 citations

Cerebral metabolic state following complete compression ischemia

1974 • 204 citations

Cerebral Effects of Hyperventilation in Man

1965 • 197 citations

PURINE NUCLEOTIDE METABOLISM IN THE CAT BRAIN AFTER ONE HOUR OF COMPLETE ISCHEMIA

1974 • 185 citations

CATECHOLAMINE CONCENTRATIONS IN CSF AND PLASMA OF PATIENTS WITH CEREBRAL INFARCTION AND HÆMORRHAGE

1973 • 181 citations

The blood-brain barrier to protein tracers in focal cerebral ischemia and infarction caused by occlusion of the middle cerebral artery

1971 • 170 citations

FREE AMINO ACIDS AND RELATED COMPOUNDS IN DOG BRAIN: POST‐MORTEM AND ANOXIC CHANGES, EFFECTS OF AMMONIUM CHLORIDE INFUSION, AND LEVELS DURING SEIZURES INDUCED BY PICROTOXIN AND BY PENTYLENETETRAZOL*

1963 • 168 citations

The measurement of regional cerebral clearance rates in man using xenon-133 inhalation and extracranial recording.

1965 • 163 citations

MICROSCOPICAL OBSERVATIONS ON THE CIRCULATION OF THE BLOOD IN THE CEREBRAL CORTEX

1925 • 162 citations

Cerebral Hyperemia in Electrically Induced Epileptic Seizures

1973 • 161 citations

Are brain vessels innervated also by central (non-sympathetic) adrenergic neurones?

1973 • 151 citations

Regional cerebral blood flow in apoplexy without arterial occlusion

1970 • 151 citations

THE EFFECTS OF INTRAVENOUSLY ADMINISTERED AMINOPHYLLINE ON CEREBRAL CIRCULATION AND METABOLISM IN MAN 1

1950 • 149 citations

The measure in vivo of regional cerebral oxygen utilization by means of oxyhemoglobin labeled with radioactive oxygen-15

1970 • 148 citations

Abbau freier Nucleotide in Herz, Skeletmuskel, Gehirn und Leber der Ratte bei Sauerstoffmangel

1966 • 145 citations

Influence of carbon monoxide and of hemodilution on cerebral blood flow and blood gases in man.

1973 • 141 citations

The Determination of Regional Cerebral Blood Flow by Means of Water Labeled with Radioactive Oxygen 15

1969 • 134 citations

THE α‐AMINOBUTYRIC ACID AND FACTOR I CONTENT OF BRAIN *

1963 • 131 citations

ENERGY METABOLITES AND WATER CONTENT IN RAT BRAIN DURING THE EARLY STAGE OF DEVELOPMENT OF CEREBRAL INFARCTION

1974 • 129 citations

Cerebral metabolism during epileptic seizures in man

1966 • 127 citations

Changes in cortical extracellular space during spreading depression investigated with the electron microscope.

1967 • 126 citations

Pressures in the Pial Arterial Microcirculation of the Cat during Changes in Systemic Arterial Blood Pressure

1972 • 123 citations

Catecholamines in Experimental Brain Ischemia

1975 • 120 citations

CEREBRAL BLOOD FLOW PRECEDING AND ACCOMPANYING EPILEPTIC SEIZURES IN MAN

1934 • 118 citations

Cerebral cortical blood flow during changes of acid-base equilibrium of the brain.

1967 • 112 citations

Effects of decapitation, ether and pentobarbital on guanosine 3′,5′-phosphate and adenosine 3′,5′-phosphate levels in rat tissues

1974 • 110 citations

Edema and Necrosis in Experimental Cerebral Infarction

1963 • 110 citations

Hydrogen transport and transport metabolites

1963 • 107 citations

Theory of the measurement of blood flow by the dilution of an indicator

1948 • 98 citations

The Effect of Ischemia on Mitochondrial Metabolism

1967 • 97 citations

Local cerebral blood volume determined by three-dimensional reconstruction of radionuclide scan data.

1975 • 96 citations

Glycolysis and the Permeation of Glucose and Lactate in the Isolated, Perfused Dog Brain during Anoxia and Postanoxic Recovery

1973 • 94 citations

Brain Energy Metabolism in Hypoxemia

1972 • 93 citations

Autonomic control of cerebral blood flow measured by electromagnetic flowmeters

1967 • 91 citations

THE INTRACELLULAR OXIDATION-REDUCTION STATE

1964 • 91 citations

TECHNIC FOR OBTAINING BLOOD FROM THE INTERNAL JUGULAR VEIN AND INTERNAL CAROTID ARTERY

1927 • 89 citations

Metabolism and function of dog's brain recovering from longtime ischemia

1972 • 88 citations

Estimation of Turnover Rates to Study the Metabolic Regulation of the Steady-State Level of Neuronal Monoamines

1970 • 87 citations

Total Cerebral Blood Flow And Metabolism

1965 • 87 citations

Metabolic Alterations in Brain During Anoxic-Anoxia and Subsequent Recovery

1973 • 86 citations

The Effect of Asphyxia upon the Lactate, Pyruvate and Bicarbonate Concentrations of Brain Tissue and Cisternal CSF, and upon the Tissue Concentrations of Phosphocreatine and Adenine Nucleotides in Anesthetized Rats

1970 • 84 citations

THE PHYSIOLOGY AND PATHOLOGY OF THE CEREBRAL CIRCULATION: AN EXPERIMENTAL RESEARCH

1896 • 84 citations

Regional cerebral blood flow: a comparison of 8-detector and 16-detector instrumentation.

1969 • 83 citations

Studies of Carotid-Artery Blood Flow in Man

1960 • 82 citations

BIOCHEMISTRY AND THE CENTRAL NERVOUS SYSTEM

1967 • 80 citations

THE INTRINSIC REGULATION OF THE BLOOD VESSELS OF THE MEDULLA OBLONGATA

1934 • 79 citations

Theory of the Measurement of the Dispersion of an Indicator in Indicator-Dilution Studies

1962 • 78 citations

Effect of Papaverine on Regional Blood Flow in Focal Vascular Disease of the Brain

1970 • 75 citations

Suppression and recovery of neuronal function in transient cerebral ischemia

1970 • 75 citations

Quantitative section scanning using orthogonal tangent correction.

1973 • 74 citations

THE INTRINSIC REGULATION OF THE CIRCULATION IN THE HYPOTHALAMUS OF THE CAT

1934 • 73 citations

THE EFFECT OF INTRAVENOUS PAPAVERINE HYDROCHLORIDE ON THE CEREBRAL CIRCULATION 12

1952 • 73 citations

Cerebral ATP and Lactate Levels in the Squirrel Monkey Following Occlusion of the Middle Cerebral Artery

1971 • 71 citations

Effect of Ischemia on Monoamine Metabolism in the Brain

1974 • 70 citations

The Effect of Intracarotid Aminophylline Infusion on the Cerebral Circulation

1972 • 69 citations

Comparison of 85krypton and 133xenon cerebral blood flow measurements before, during, and following focal, incomplete ischemia in the squirrel monkey.

1975 • 68 citations

Regional changes in cerebral blood volume during mental activity

1968 • 68 citations

CIRCULATION AND METABOLISM FOLLOWING EXPERIMENTAL CEREBRAL EMBOLISM

1962 • 67 citations

The state of Factor I in rat brain: the effects of metabolic conditions and drugs

1960 • 64 citations

Cerebral blood flow after control of hypertension in stroke

1968 • 62 citations

Effect of experimental ischemia on cerebral water and electrolytes

1974 • 62 citations

Studies on vertebral artery blood flow in man.

1963 • 61 citations

Ischemic anoxia and cerebral serotonin levels

1972 • 61 citations

The blood flow and oxygen consumption of the dying brain

1970 • 60 citations

THE PRESENCE OF BIOLOGICALLY LABILE COMPOUNDS DURING ISCHEMIA AND THEIR RELATIONSHIP TO THE EEG IN RAT CEREBRAL CORTEX AND HYPOTHALAMUS

1972 • 60 citations

The effects of mannitol and urea on cerebral hemodynamics and cerebrospinal fluid pressure

1964 • 60 citations

Regional Cerebral Blood Flow in Patients With Brain Infarcts

1966 • 53 citations

REGIONAL CEREBRAL BLOOD FLOW RELATED TO EEG

2009 • 53 citations

In vivo regional cerebral blood volume by x-ray fluorescence: validation of method.

1973 • 53 citations

X-ray microscopy and histochemistry of the human cerebral blood vessels

1971 • 51 citations

Some effects of hypoxia on respiratory metabolism and protein synthesis in rat tissues

1965 • 51 citations

Pathophysiology of Anoxic Brain Damage

1973 • 50 citations

Cerebral Blood Flow and Internal Carotid Artery Flow During Carotid Surgery

1970 • 50 citations

Cerebral Energy Metabolism

1985 • 49 citations

Aminergic transmission. Introduction and short review

1973 • 48 citations

Mathematical considerations of indicator dilution techniques.

1954 • 48 citations

On the reflex regulation of the cerebral blood flow and the cerebral vaso‐motor tone

1935 • 46 citations

MEASUREMENT OF THE CEPHALIC AND CEREBRAL BLOOD FLOW FRACTIONS OF THE CARDIAC OUTPUT IN MAN*

1962 • 45 citations

Brain dysfunction in cerebral hypoxia and ischemia.

1974 • 44 citations

Orally Administered Betahistine and Regional Cerebral Blood Flow in Cerebrovascular Disease

1974 • 42 citations

The Lactate/Pyruvate Ratios of Cerebrospinal Fluid of Rats and Cats Related to the Lactate/Pyruvate, the ATP/ADP, and the Phosphocreatine/Creatine Ratios of Brain Tissue

1968 • 39 citations

Hydrogen Method for Determining Cerebral Blood Flow in Man

1966 • 39 citations

Hemodynamic and metabolic concomitants of brain swelling and cerebral edema due to experimental cerebral infarction

1972 • 39 citations

A role of cyclic nucleotides in brain metabolism.

1970 • 38 citations

On the Location of the Vascular Resistance in the Cerebral Circulation

1969 • 37 citations

Alteration of Rat Brain Catecholamine Metabolism During Exposure to Hypobaric Hypoxia

1972 • 37 citations

INFLUENCE OF STAGNANT HYPOXIA (OLIGAEMIA) ON SOME FREE AMINO ACIDS IN RAT BRAIN DURING ONTOGENY

1965 • 35 citations

Regional cerebral blood flow and blood volume measured with the gamma camera

1972 • 34 citations

THE EFFECTS OF OXYGEN DEPRIVATION ON ELECTRICALLY STIMULATED CEREBRAL CORTEX SLICES

1969 • 34 citations

Cerebral Metabolic Changes During Treatment of Subacute Cerebral Infarction by Alpha and Beta Adrenergic Blockade With Phenoxybenzamine and Propranolol

1974 • 33 citations

Cerebral high-energy compounds: changes in anoxia

1962 • 33 citations

Diagnosis and treatment of factors complicating subarachnoid hemorrhage

1974 • 32 citations

Regional blood flow in deep structures of the brain measured in acute cat experiments by means of a new beta-sensitive semiconductor needle detector

1967 • 31 citations

REGIONAL CEREBRAL BLOOD FLOW IN CEREBROVASCULAR DISEASE

2009 • 31 citations

The Value of Regional Cerebral Blood Flow Measurements Compared to Angiography in the Assessment of Obstructive Neck Vessel Disease

1974 • 28 citations

Cerebral metabolic effects of glycerol infusion in diabetics with stroke

1974 • 25 citations

Behavioral and neurochemical alterations induced by hypoxia in rats

1974 • 23 citations

Redistribution of regional cerebral blood flow after glycerol infusion in acute cerebral infarction

1974 • 23 citations

Edema of the brain following circulatory arrest

1962 • 21 citations

Evidence for a Pasteur effect regulating cerebral oxygen and carbohydrate metabolism in man

1969 • 21 citations

Effects of carotid compression on cerebral metabolism and electroencephalogram

1965 • 21 citations

Abnormal Hemispheric Blood Flow and Metabolism Despite Normal Angiograms in Patients with Stroke

1970 • 20 citations

The Influence of Anoxia on Respiratory Enzymes in Rat Brain

1963 • 20 citations

Effect of hexobendine on cerebral hemispheric blood flow and metabolism

1971 • 18 citations

LIPID BIOSYNTHESIS IN ANOXIC‐ISCHAEMIC RAT BRAIN*

1966 • 17 citations

Histochemical studies in the zone of ischemia following middle cerebral artery occlusion in cats

1972 • 17 citations

Cerebral blood flow measurements and electroencephalograms during carotid endarterectomy.

2007 • 17 citations

THE INCORPORATION OF GLUCOSE INTO BRAIN GLYCOGEN AND THE ACTIVITIES OF CEREBRAL GLYCOGEN PHOSPHORYLASE AND SYNTHETASE: SOME EFFECTS OF AMPHETAMINE

1974 • 16 citations

Cerebral protein synthesis in anoxic‐ischaemic brain injury in the rat

1965 • 16 citations

CEREBRAL METABOLISM DURING AROUSAL AND MENTAL ACTIVITY IN STROKE PATIENTS*

1966 • 15 citations

EFFECT OF ERGOTAMINE TARTRATE ON THE CEREBRAL CIRCULATION OF MAN

1935 • 15 citations

PATHOGENESIS OF HYPERTENSIVE ENCEPHALOPATHY

1973 • 14 citations

Vascular and neuronal factors in diaschisis with focal cerebral ischemia.

1966 • 14 citations

Metabolism: Carbohydrate

2012 • 12 citations

THE EFFECT OF THE COMPOSITION OF THE INSPIRED AIR ON THE CIRCULATION THROUGH THE BRAIN

1935 • 11 citations

THE MEASUREMENT OF CEREBRAL BLOOD FLOW BY EXTERNAL ISOTOPE COUNTING*

1962 • 11 citations

Abnormal Hemispheric Blood Flow and Metabolism in Cerebrovascular Disease. I. Disordered Patterns of Hemispheric Metabolism

1972 • 9 citations

Hemispheric blood flow and metabolism in neurological disease--a note on the metabolic accompaniments of diaschisis.

1969 • 9 citations

Carbonic anhydrase inhibition and cerebral venous blood gases and ions in man. Demonstration of increased oxygen availability to ischemic brain

1966 • 6 citations

Improvement in brain oxygenation and clinical improvement in patients with strokes treated with papaverine hydrochloride

1965 • 6 citations

Biochemical characteristics of experimental cerebral infarction: Evidence against lysosomal participation in early cell injury.

1969 • 6 citations

Acute and Chronic Effects of Unilateral Cerebral Infarction on the EEG and Behavior of the Rat

1974 • 5 citations

The pharmacology of brain blood flow.

1966 • 4 citations

Studies on Cerebral Blood Flow in Man Using Radioactive-Labelled Erythrocytes

1961 • 3 citations

Function of brain mitochondria after profound hypoxemia.

1972 • 2 citations

Cellular Foundations of Neuropharmacology

2002 • 2 citations

Dynamics of changes in blood vessels of the cerebral cortex during the development of postischemic edema

1965 • 2 citations

In Vivo Measurement of Cerebral Glucose Metabolism Employing 11C-Labeled Glucose

1975 • 2 citations

Regional Cerebral Blood Flow in Patients With Hypertensive Intracerebral Hemorrhage

1974 • 2 citations